Assessment of Structural Intolerance and Durability
General Structure Information 3nr1 HDDC3 a metazoan ortholog of spot hydrolyzes ppgpp and plays a role in starvation responses 1.9Å AUTH D.W.SUN,G.LEE,J.H.LEE,H.Y.KIM,H.W.RHEE,S.Y.PARK,K.J.KIM,AUTH 2 Y.KIM,B.Y.KIM,J.I.HONG,C.PARK,H.E.CHOY,J.H.KIM,Y.H.JEON,AUTH 3 J.CHUNGTITL A METAZOAN ORTHOLOG OF SPOT HYDROLYZES PPGPP AND FUNCTIONSTITL 2 IN STARVATION RESPONSESREF NAT.STRUCT.MOL.BIOL. V. 17 1188 2010REFN ISSN 1545-9993PMID 20818390DOI 10.1038/NSMB.1906 Variant Set Distributions Mapped Variants
General Structure Information 2oo4 NOTCH2 structure of lnr-hd (negative regulatory region) from human notch 2 2.0Å AUTH W.R.GORDON,D.VARDAR-ULU,G.HISTEN,C.SANCHEZ-IRIZARRY,AUTH 2 J.C.ASTER,S.C.BLACKLOWTITL STRUCTURAL BASIS FOR AUTOINHIBITION OF NOTCHREF NAT.STRUCT.MOL.BIOL. V. 14 295 2007REFN ISSN 1545-9993PMID 17401372DOI 10.1038/NSMB1227 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2oo4 NOTCH2 structure of lnr-hd (negative regulatory region) from human notch 2 2.0Å AUTH W.R.GORDON,D.VARDAR-ULU,G.HISTEN,C.SANCHEZ-IRIZARRY,AUTH 2 J.C.ASTER,S.C.BLACKLOWTITL STRUCTURAL BASIS FOR AUTOINHIBITION OF NOTCHREF NAT.STRUCT.MOL.BIOL. V. 14 295 2007REFN ISSN 1545-9993PMID 17401372DOI 10.1038/NSMB1227 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3eto NOTCH1 2 angstrom xray structure of the notch1 negative regulatory region (nrr) 2.0Å AUTH W.R.GORDON,M.ROY,D.VARDAR-ULU,M.GARFINKEL,M.R.MANSOUR,AUTH 2 J.C.ASTER,S.C.BLACKLOWTITL STRUCTURE OF THE NOTCH1-NEGATIVE REGULATORY REGION:TITL 2 IMPLICATIONS FOR NORMAL ACTIVATION AND PATHOGENIC SIGNALINGTITL 3 IN T-ALL.REF BLOOD V. 113 4381 2009REFN ISSN 0006-4971PMID 19075186DOI 10.1182/BLOOD-2008-08-174748 Variant Set Distributions Ripley’s K Analysis Plots Variant […]