Assessment of Structural Intolerance and Durability
General Structure Information 1wji TDRD3 solution structure of the uba domain of human tudor domain containing protein 3 -1.0Å AUTH Y.O.KAMATARI,N.TOCHIO,T.NAKANISHI,K.MIYAMOTO,H.LI,AUTH 2 N.KOBAYASHI,T.TOMIZAWA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 3 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE UBA DOMAIN OF HUMANTITL 2 TUDOR DOMAIN CONTAINING PROTEIN 3REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3fk2 ARHGAP35 crystal structure of the rhogap domain of human glucocorticoid receptor dna-binding factor 1 2.8Å AUTH L.NEDYALKOVA,Y.TONG,W.TEMPEL,P.LOPPNAU,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE RHOGAP DOMAIN OF HUMANTITL 2 GLUCOCORTICOID RECEPTOR DNA-BINDING FACTOR 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1x3s RAB18 crystal structure of human rab18 in complex with gppnhp 1.32Å AUTH M.KUKIMOTO-NIINO,K.MURAYAMA,L.CHEN,Z.J.LIU,AUTH 2 B.C.WANG,M.SHIROUZU,S.YOKOYAMATITL CRYSTAL STRUCTURE OF HUMAN RAB18 IN COMPLEX WITHTITL 2 GPPNHPREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3pnw TDRD3 crystal structure of the tudor domain of human tdrd3 in complex with an anti-tdrd3 fab 2.05Å AUTH H.PERSSON,W.YE,A.WERNIMONT,J.J.ADAMS,A.KOIDE,S.KOIDE,R.LAM,AUTH 2 S.S.SIDHUTITL CDR-H3 DIVERSITY IS NOT REQUIRED FOR ANTIGEN RECOGNITION BYTITL 2 SYNTHETIC ANTIBODIES.REF J.MOL.BIOL. V. 425 803 2013REFN ISSN 0022-2836PMID 23219464DOI 10.1016/J.JMB.2012.11.037 Variant Set Distributions Mapped Variants
General Structure Information 2eeh PDZD7 solution structure of first pdz domain of pdz domain containing protein 7 -1.0Å AUTH T.N.NIRAULA,N.TOCHIO,T.TOMIZAWA,K.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF FIRST PDZ DOMAIN OF PDZTITL 2 DOMAIN CONTAINING PROTEIN 7REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2gwf RNF41 structure of a usp8-nrdp1 complex 2.3Å AUTH G.V.AVVAKUMOV,J.R.WALKER,S.XUE,P.J.FINERTY JR.,F.MACKENZIE,AUTH 2 E.M.NEWMAN,S.DHE-PAGANONTITL AMINO-TERMINAL DIMERIZATION, NRDP1-RHODANESE INTERACTION,TITL 2 AND INHIBITED CATALYTIC DOMAIN CONFORMATION OF THETITL 3 UBIQUITIN-SPECIFIC PROTEASE 8 (USP8).REF J.BIOL.CHEM. V. 281 38061 2006REFN ISSN 0021-9258PMID 17035239DOI 10.1074/JBC.M606704200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2ex4 NTMT1 crystal structure of human methyltransferase ad-003 in complex with s-adenosyl-l-homocysteine 1.75Å AUTH J.MIN,H.WU,H.ZENG,P.LOPPNAU,M.SUNDSTROM,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,AUTH 3 A.N.PLOTNIKOVTITL THE CRYSTAL STRUCTURE OF HUMAN AD-003 PROTEIN INTITL 2 COMPLEX WITH S-ADENOSYL-L-HOMOCYSTEINEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2yra SEZ6L solution structure of the zinc finger domains (1-87) from human f-box only protein -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ZINC FINGER DOMAINSTITL 2 (1-87) FROM HUMAN F-BOX ONLY PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4h87 SLC4A1AP crystal structure of a fha domain of kanadaptin (slc4a1ap) from homo sapiens at 1.55 a resolution 1.55Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG)TITL CRYSTAL STRUCTURE OF A FHA DOMAIN OF KANADAPTIN (SLC4A1AP)TITL 2 FROM HOMO SAPIENS AT 1.55 A RESOLUTIONREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dgt RBM4B solution structure of the second rna binding domain in rna- binding protein 30 -1.0Å AUTH C.ABE,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,M.SHIROUZU,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND RNA BINDINGTITL 2 DOMAIN IN RNA-BINDING PROTEIN 30REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants