Assessment of Structural Intolerance and Durability
General Structure Information 2hzd TEAD1 nmr structure of the dna-binding tea domain and insights into tef-1 function -1.0Å AUTH A.ANBANANDAM,D.C.ALBARADO,C.T.NGUYEN,G.HALDER,AUTH 2 X.GAO,S.VEERARAGHAVANTITL INSIGHTS INTO TRANSCRIPTION ENHANCER FACTOR 1TITL 2 (TEF-1) ACTIVITY FROM THE SOLUTION STRUCTURE OFTITL 3 THE TEA DOMAIN.REF PROC.NATL.ACAD.SCI.USA V. 103 17225 2006REFN ISSN 0027-8424PMID 17085591DOI 10.1073/PNAS.0607171103 Variant Set Distributions Mapped Variants
General Structure Information 1fd0 RARG isotype selectivity of the human retinoic acid nuclear receptor hrar: the complex with the rargamma-selective retinoid sr11254 1.38Å AUTH B.KLAHOLZ,D.MORASTITL C-H…O HYDROGEN BONDS IN THE NUCLEAR RECEPTORTITL 2 RARGAMMA–A POTENTIAL TOOL FOR DRUG SELECTIVITY.REF STRUCTURE V. 10 1197 2002REFN ISSN 0969-2126PMID 12220491DOI 10.1016/S0969-2126(02)00828-6 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 2hb8 VDR crystal structure of vdr lbd in complex with 2alpha-methyl calcitriol 2.0Å AUTH S.HOURAI,T.FUJISHIMA,A.KITTAKA,Y.SUHARA,H.TAKAYAMA,AUTH 2 N.ROCHEL,D.MORASTITL PROBING A WATER CHANNEL NEAR THE A-RING OFTITL 2 RECEPTOR-BOUND 1ALPHA,25-DIHYDROXYVITAMIN D3 WITHTITL 3 SELECTED 2ALPHA-SUBSTITUTED ANALOGUESREF J.MED.CHEM. V. 49 5199 2006REFN ISSN 0022-2623PMID 16913708DOI 10.1021/JM0604070 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 3a03 TLX2 crystal structure of hox11l1 homeodomain 1.54Å AUTH K.MIYAZONO,Y.ZHI,Y.TAKAMURA,K.NAGATA,K.SAIGO,T.KOJIMA,AUTH 2 M.TANOKURATITL COOPERATIVE DNA-BINDING AND SEQUENCE-RECOGNITION MECHANISMTITL 2 OF ARISTALESS AND CLAWLESSREF EMBO J. V. 29 1613 2010REFN ISSN 0261-4189PMID 20389279DOI 10.1038/EMBOJ.2010.53 Variant Set Distributions Mapped Variants
General Structure Information 1zr3 H2AFY crystal structure of the macro-domain of human core histone variant macroh2a1.1 (form b) 1.66Å AUTH G.KUSTATSCHER,M.HOTHORN,C.PUGIEUX,K.SCHEFFZEK,A.G.LADURNERTITL SPLICING REGULATES NAD METABOLITE BINDING TO HISTONETITL 2 MACROH2A.REF NAT.STRUCT.MOL.BIOL. V. 12 624 2005REFN ISSN 1545-9993PMID 15999106DOI 10.1038/NSMB956 Variant Set Distributions Mapped Variants
General Structure Information 1e4u CNOT4 n-terminal ring finger domain of human not-4 -1.0Å AUTH H.HANZAWA,M.J.DE RUWE,T.K.ALBERT,P.C.VAN DER VLIET,AUTH 2 H.T.TIMMERS,R.BOELENSTITL THE STRUCTURE OF THE C4C4 RING FINGER OF HUMANTITL 2 NOT4 REVEALS FEATURES DISTINCT FROM THOSE OF C3HC4TITL 3 RING FINGERSREF J.BIOL.CHEM. V. 276 10185 2001REFN ISSN 0021-9258PMID 11087754DOI 10.1074/JBC.M009298200 Variant Set Distributions Mapped Variants
General Structure Information 3k27 EED complex structure of eed and trimethylated h3k9 1.76Å AUTH C.XU,C.BIAN,W.YANG,M.GALKA,H.OUYANG,C.CHEN,W.QIU,H.LIU,AUTH 2 A.E.JONES,F.MACKENZIE,P.PAN,S.S.LI,H.WANG,J.MINTITL BINDING OF DIFFERENT HISTONE MARKS DIFFERENTIALLY REGULATESTITL 2 THE ACTIVITY AND SPECIFICITY OF POLYCOMB REPRESSIVE COMPLEXTITL 3 2 (PRC2).REF PROC.NATL.ACAD.SCI.USA V. 107 19266 2010REFN ISSN 0027-8424PMID 20974918DOI 10.1073/PNAS.1008937107 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 4c0d CNOT3 structure of the not module of the human ccr4-not complex (cnot1-cnot2-cnot3) 3.2Å AUTH A.BOLAND,Y.CHEN,T.RAISCH,S.JONAS,D.KUZUOGLU-OZTURK,AUTH 2 L.WOHLBOLD,O.WEICHENRIEDER,E.IZAURRALDETITL STRUCTURE AND ASSEMBLY OF THE NOT MODULE OF THE HUMANTITL 2 CCR4-NOT COMPLEXREF NAT.STRUCT.MOL.BIOL. V. 20 1289 2013REFN ISSN 1545-9993PMID 24121232DOI 10.1038/NSMB.2681 Variant Set Distributions Mapped Variants
General Structure Information 2vpd BCL9 decoding of methylated histone h3 tail by the pygo-bcl9 wnt signaling complex 2.77Å AUTH M.FIEDLER,M.J.SANCHEZ-BARRENA,M.NEKRASOV,AUTH 2 J.MIESZCZANEK,V.RYBIN,J.MULLER,P.EVANS,M.BIENZTITL DECODING OF METHYLATED HISTONE H3 TAIL BY THETITL 2 PYGO- BCL9 WNT SIGNALING COMPLEX.REF MOL.CELL V. 30 507 2008REFN ISSN 1097-2765PMID 18498752DOI 10.1016/J.MOLCEL.2008.03.011 Variant Set Distributions Mapped Variants
General Structure Information 2dk2 HNRNPR solution structure of rrm domain in heterogeneous nuclear ribonucleoprotein r (hnrnp r) -1.0Å AUTH F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF RRM DOMAIN IN HETEROGENEOUSTITL 2 NUCLEAR RIBONUCLEOPROTEIN R (HNRNP R)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants