Assessment of Structural Intolerance and Durability
General Structure Information 2crw ARFGAP3 solution structure of the arfgap domain of adp-ribosylation factor gtpaseactivating protein 3 (arfgap 3) -1.0Å AUTH H.P.ZHANG,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ARFGAP DOMAIN OFTITL 2 ADP-RIBOSYLATION FACTOR GTPASEACTIVATING PROTEIN 3TITL 3 (ARFGAP 3)REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]
General Structure Information 3fm8 KIF13B crystal structure of full length centaurin alpha-1 bound with the fha domain of kif13b (capri target) 2.3Å AUTH Y.TONG,W.TEMPEL,H.WANG,K.YAMADA,L.SHEN,G.A.SENISTERRA,AUTH 2 F.MACKENZIE,A.H.CHISHTI,H.W.PARKTITL PHOSPHORYLATION-INDEPENDENT DUAL-SITE BINDING OF THE FHATITL 2 DOMAIN OF KIF13 MEDIATES PHOSPHOINOSITIDE TRANSPORT VIATITL 3 CENTAURIN ALPHA1.REF PROC.NATL.ACAD.SCI.USA V. 107 20346 2010REFN ISSN 0027-8424PMID 21057110DOI 10.1073/PNAS.1009008107 Variant Set Distributions […]
General Structure Information 4i1o RAB1B crystal structure of the legionella pneumophila gap domain of lepb in complex with rab1b bound to gdp and bef3 2.7Å AUTH E.MIHAI GAZDAG,A.STRELLER,I.HANEBURGER,H.HILBI,I.R.VETTER,AUTH 2 R.S.GOODY,A.ITZENTITL MECHANISM OF RAB1B DEACTIVATION BY THE LEGIONELLATITL 2 PNEUMOPHILA GAP LEPB.REF EMBO REP. V. 14 199 2013REFN ISSN 1469-221XPMID 23288104DOI 10.1038/EMBOR.2012.211 Variant Set Distributions Ripley’s […]
General Structure Information 2cod ARAP2 solution structure of the n-terminal ph domain of arap2 protein from human -1.0Å AUTH H.LI,T.TOMIZAWA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE N-TERMINAL PH DOMAIN OFTITL 2 ARAP2 PROTEIN FROM HUMANREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2p57 ARFGAP2 gap domain of znf289, an id1-regulated zinc finger protein 1.8Å AUTH Y.TONG,S DIMOV,L.SHEN,H.ZHU,W.TEMPEL,R.LANDRY,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL GAP DOMAIN OF ZNF289, AN ID1-REGULATED ZINC FINGERTITL 2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3eap ARHGAP11A crystal structure of the rhogap domain of arhgap11a 2.3Å AUTH Y.SHEN,L.SHEN,Y.TONG,W.TEMPEL,F.MACKENZIE,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE RHOGAP DOMAIN OF ARHGAP11AREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3iez IQGAP2 crystal structure of the rasgap c-terminal (rgc) domain of iqgap2 1.5Å AUTH L.NEDYALKOVA,W.TEMPEL,Y.TONG,N.ZHONG,L.CROMBET,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE RASGAP C-TERMINAL (RGC)TITL 2 DOMAIN OF IQGAP2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1grn ARHGAP1 crystal structure of the cdc42/cdc42gap/alf3 complex. 2.1Å AUTH N.NASSAR,G.R.HOFFMAN,D.MANOR,J.C.CLARDY,R.A.CERIONETITL STRUCTURES OF CDC42 BOUND TO THE ACTIVE ANDTITL 2 CATALYTICALLY COMPROMISED FORMS OF CDC42GAP.REF NAT.STRUCT.BIOL. V. 5 1047 1998REFN ISSN 1072-8368PMID 9846874DOI 10.1038/4156 Variant Set Distributions Mapped Variants
General Structure Information 1grn ARHGAP1 crystal structure of the cdc42/cdc42gap/alf3 complex. 2.1Å AUTH N.NASSAR,G.R.HOFFMAN,D.MANOR,J.C.CLARDY,R.A.CERIONETITL STRUCTURES OF CDC42 BOUND TO THE ACTIVE ANDTITL 2 CATALYTICALLY COMPROMISED FORMS OF CDC42GAP.REF NAT.STRUCT.BIOL. V. 5 1047 1998REFN ISSN 1072-8368PMID 9846874DOI 10.1038/4156 Variant Set Distributions Mapped Variants
General Structure Information 1grn ARHGAP1 crystal structure of the cdc42/cdc42gap/alf3 complex. 2.1Å AUTH N.NASSAR,G.R.HOFFMAN,D.MANOR,J.C.CLARDY,R.A.CERIONETITL STRUCTURES OF CDC42 BOUND TO THE ACTIVE ANDTITL 2 CATALYTICALLY COMPROMISED FORMS OF CDC42GAP.REF NAT.STRUCT.BIOL. V. 5 1047 1998REFN ISSN 1072-8368PMID 9846874DOI 10.1038/4156 Variant Set Distributions Mapped Variants