General Structure Information
| PDB ID | 2crw |
| HGNC Gene Label(s) | ARFGAP3 |
| Structure Name | solution structure of the arfgap domain of adp-ribosylation factor gtpaseactivating protein 3 (arfgap 3) |
| Resolution | -1.0Å |
| Reference | AUTH H.P.ZHANG,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ARFGAP DOMAIN OFTITL 2 ADP-RIBOSYLATION FACTOR GTPASEACTIVATING PROTEIN 3TITL 3 (ARFGAP 3)REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 136 |
| Number Of SNVs | 35 |
| Number Of Permutations | 3177 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.029 |
| p-value | 0.831 |
COSMIC
| Number Of Residues | 136 |
| Number Of SNVs | 4 |
| Number Of Permutations | 16 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.333 |
| p-value | 0.408 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 35 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.512 |
| p-value | 0.214 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
