General Structure Information 1zs9 ENOPH1 crystal structure of human enolase-phosphatase e1 1.7Å AUTH H.WANG,H.PANG,M.BARTLAM,Z.RAOTITL CRYSTAL STRUCTURE OF HUMAN E1 ENZYME AND ITSTITL 2 COMPLEX WITH A SUBSTRATE ANALOG REVEALS THETITL 3 MECHANISM OF ITS PHOSPHATASE/ENOLASEREF J.MOL.BIOL. V. 348 917 2005REFN ISSN 0022-2836PMID 15843022DOI 10.1016/J.JMB.2005.01.072 Variant Set Distributions Mapped Variants
General Structure Information 1y8r UBA2 sumo e1 activating enzyme sae1-sae2-sumo1-mg-atp complex 2.75Å AUTH L.M.LOIS,C.D.LIMATITL STRUCTURES OF THE SUMO E1 PROVIDE MECHANISTICTITL 2 INSIGHTS INTO SUMO ACTIVATION AND E2 RECRUITMENTTITL 3 TO E1REF EMBO J. V. 24 439 2005REFN ISSN 0261-4189PMID 15660128DOI 10.1038/SJ.EMBOJ.7600552 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 1y8r SAE1 sumo e1 activating enzyme sae1-sae2-sumo1-mg-atp complex 2.75Å AUTH L.M.LOIS,C.D.LIMATITL STRUCTURES OF THE SUMO E1 PROVIDE MECHANISTICTITL 2 INSIGHTS INTO SUMO ACTIVATION AND E2 RECRUITMENTTITL 3 TO E1REF EMBO J. V. 24 439 2005REFN ISSN 0261-4189PMID 15660128DOI 10.1038/SJ.EMBOJ.7600552 Variant Set Distributions Mapped Variants
General Structure Information 2nvu UBA3 structure of appbp1-uba3~nedd8-nedd8-mgatp-ubc12(c111a), a trapped ubiquitin-like protein activation complex 2.8Å AUTH D.T.HUANG,H.W.HUNT,M.ZHUANG,M.D.OHI,J.M.HOLTON,AUTH 2 B.A.SCHULMANTITL BASIS FOR A UBIQUITIN-LIKE PROTEIN THIOESTERTITL 2 SWITCH TOGGLING E1-E2 AFFINITY.REF NATURE V. 445 394 2007REFN ISSN 0028-0836PMID 17220875DOI 10.1038/NATURE05490 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ozl PDHA1 human pyruvate dehydrogenase s264e variant 1.9Å AUTH F.SEIFERT,E.M.CISZAK,L.G.KOROTCHKINA,R.GOLBIK,AUTH 2 M.SPINKA,P.M.DOMINIAK,S.SIDHU,J.BRAUER,M.S.PATEL,AUTH 3 K.TITTMANNTITL PHOSPHORYLATION OF SERINE 264 IMPEDES ACTIVE SITETITL 2 ACCESSIBILITY IN THE E1 COMPONENT OF THE HUMANTITL 3 PYRUVATE DEHYDROGENASE MULTIENZYME COMPLEXREF BIOCHEMISTRY V. 46 6277 2007REFN ISSN 0006-2960PMID 17474719DOI 10.1021/BI700083Z Variant Set Distributions Ripley’s K Analysis Plots Variant […]