Assessment of Structural Intolerance and Durability
General Structure Information 2k40 HESX1 nmr structure of hesx-1 homeodomain double mutant r31l/e42l -1.0Å AUTH J.ASENSIO,M.TORRADO,C.GONZALEZ,A.BASTIDA,F.CORZANATITL THE ROLE OF CONSERVED SALT-BRIDGES ON HOMEODOMAINTITL 2 STABILITYREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2wt8 MCPH1 structure of the n-terminal brct domain of human microcephalin (mcph1) 1.6Å AUTH M.W.RICHARDS,J.W.C.LEUNG,S.M.ROE,J.CHEN,R.BAYLISSTITL A POCKET ON THE SURFACE OF THE N-TERMINAL BRCTTITL 2 DOMAIN OF MCPH1 IS REQUIRED TO PREVENT ABNORMALTITL 3 CHROMOSOME CONDENSATION.REF J.MOL.BIOL. V. 395 908 2010REFN ISSN 0022-2836PMID 19925808DOI 10.1016/J.JMB.2009.11.029 Variant Set Distributions Pathogenic Proximity Analysis Mapped […]
General Structure Information 3fby COMP the crystal structure of the signature domain of cartilage oligomeric matrix protein. 3.15Å AUTH K.TAN,M.DUQUETTE,A.JOACHIMIAK,J.LAWLERTITL THE CRYSTAL STRUCTURE OF THE SIGNATURE DOMAIN OF CARTILAGETITL 2 OLIGOMERIC MATRIX PROTEIN: IMPLICATIONS FOR COLLAGEN,TITL 3 GLYCOSAMINOGLYCAN AND INTEGRIN BINDING.REF FASEB J. V. 23 2490 2009REFN ISSN 0892-6638PMID 19276170DOI 10.1096/FJ.08-128090 Variant Set Distributions Ripley’s […]
General Structure Information 3evs GDF5 crystal structure of the gdf-5:bmp receptor ib complex. 2.1Å AUTH A.KOTZSCH,J.NICKEL,A.SEHER,W.SEBALD,T.D.MULLERTITL CRYSTAL STRUCTURE ANALYSIS REVEALS A SPRING-LOADED LATCH ASTITL 2 MOLECULAR MECHANISM FOR GDF-5-TYPE I RECEPTOR SPECIFICITY.REF EMBO J. V. 28 937 2009REFN ISSN 0261-4189PMID 19229295DOI 10.1038/EMBOJ.2009.37 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants