Assessment of Structural Intolerance and Durability
General Structure Information 1fd0 RARG isotype selectivity of the human retinoic acid nuclear receptor hrar: the complex with the rargamma-selective retinoid sr11254 1.38Å AUTH B.KLAHOLZ,D.MORASTITL C-H…O HYDROGEN BONDS IN THE NUCLEAR RECEPTORTITL 2 RARGAMMA–A POTENTIAL TOOL FOR DRUG SELECTIVITY.REF STRUCTURE V. 10 1197 2002REFN ISSN 0969-2126PMID 12220491DOI 10.1016/S0969-2126(02)00828-6 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 1ebp EPOR complex between the extracellular domain of erythropoietin (epo) receptor [ebp] and an agonist peptide [emp1] 2.8Å AUTH O.LIVNAH,E.A.STURA,D.L.JOHNSON,S.A.MIDDLETON,AUTH 2 L.S.MULCAHY,N.C.WRIGHTON,W.J.DOWER,L.K.JOLLIFFE,AUTH 3 I.A.WILSONTITL FUNCTIONAL MIMICRY OF A PROTEIN HORMONE BY ATITL 2 PEPTIDE AGONIST: THE EPO RECEPTOR COMPLEX AT 2.8 A.REF SCIENCE V. 273 464 1996REFN ISSN 0036-8075PMID 8662530 Variant Set […]
General Structure Information 4kp5 CA12 crystal structure of catalytic domain of human carbonic anhydrase isozyme xii with 2-chloro-4-[(pyrimidin-2-ylsulfanyl) acetyl]benzenesulfonamide 1.45Å AUTH E.CAPKAUSKAITE,A.ZUBRIENE,A.SMIRNOV,J.TORRESAN,M.KISONAITE,AUTH 2 J.KAZOKAITE,J.GYLYTE,V.MICHAILOVIENE,V.JOGAITE,E.MANAKOVA,AUTH 3 S.GRAZULIS,S.TUMKEVICIUS,D.MATULISTITL BENZENESULFONAMIDES WITH PYRIMIDINE MOIETY AS INHIBITORS OFTITL 2 HUMAN CARBONIC ANHYDRASES I, II, VI, VII, XII, AND XIIIREF BIOORG.MED.CHEM. V. 21 6937 2013REFN ISSN 0968-0896PMID 24103428DOI 10.1016/J.BMC.2013.09.029 Variant Set […]