General Structure Information
| PDB ID | 4kp5 |
| HGNC Gene Label(s) | CA12 |
| Structure Name | crystal structure of catalytic domain of human carbonic anhydrase isozyme xii with 2-chloro-4-[(pyrimidin-2-ylsulfanyl) acetyl]benzenesulfonamide |
| Resolution | 1.45Å |
| Reference | AUTH E.CAPKAUSKAITE,A.ZUBRIENE,A.SMIRNOV,J.TORRESAN,M.KISONAITE,AUTH 2 J.KAZOKAITE,J.GYLYTE,V.MICHAILOVIENE,V.JOGAITE,E.MANAKOVA,AUTH 3 S.GRAZULIS,S.TUMKEVICIUS,D.MATULISTITL BENZENESULFONAMIDES WITH PYRIMIDINE MOIETY AS INHIBITORS OFTITL 2 HUMAN CARBONIC ANHYDRASES I, II, VI, VII, XII, AND XIIIREF BIOORG.MED.CHEM. V. 21 6937 2013REFN ISSN 0968-0896PMID 24103428DOI 10.1016/J.BMC.2013.09.029 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 260 |
| Number Of SNVs | 64 |
| Number Of Permutations | 23021 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.287 |
| p-value | 0.435 |