General Structure Information 3qxm GRIK2 crystal structure of human gluk2 ligand-binding core in complex with novel marine-derived toxins, neodysiherbaine a 1.65Å AUTH M.UNNO,M.SHINOHARA,K.TAKAYAMA,H.TANAKA,K.TERUYA,K.DOH-URA,AUTH 2 R.SAKAI,M.SASAKI,M.IKEDA-SAITOTITL BINDING AND SELECTIVITY OF THE MARINE TOXIN NEODYSIHERBAINETITL 2 A AND ITS SYNTHETIC ANALOGUES TO GLUK1 AND GLUK2 KAINATETITL 3 RECEPTORS.REF J.MOL.BIOL. V. 413 667 2011REFN ISSN 0022-2836PMID 21893069DOI 10.1016/J.JMB.2011.08.043 […]
General Structure Information 2qnd FMR1 crystal structure of the kh1-kh2 domains from human fragile x mental retardation protein 1.9Å AUTH R.VALVERDE,I.POZDNYAKOVA,T.KAJANDER,J.VENKATRAMAN,L.REGANTITL FRAGILE X MENTAL RETARDATION SYNDROME: STRUCTURE OF THETITL 2 KH1-KH2 DOMAINS OF FRAGILE X MENTAL RETARDATION PROTEIN.REF STRUCTURE V. 15 1090 2007REFN ISSN 0969-2126PMID 17850748DOI 10.1016/J.STR.2007.06.022 Variant Set Distributions Mapped Variants
General Structure Information 2v4m GFPT1 the isomerase domain of human glutamine-fructose-6- phosphate transaminase 1 (gfpt1) in complex with fructose 6-phosphate 2.29Å AUTH M.MOCHE,L.LEHTIO,J.ANDERSSON,C.H.ARROWSMITH,AUTH 2 H.BERGLUND,R.COLLINS,L.G.DAHLGREN,A.M.EDWARDS,AUTH 3 S.FLODIN,A.FLORES,S.GRASLUND,M.HAMMARSTROM,AUTH 4 A.JOHANSSON,I.JOHANSSON,T.KARLBERG,T.KOTENYOVA,AUTH 5 M.E.NILSSON,T.NYMAN,C.PERSSON,J.SAGEMARK,AUTH 6 S.SVENSSON,H.SCHUELER,A.G.THORSELL,L.TRESAUGUES,AUTH 7 J.UPPENBERG,S.VAN DEN BERG,M.WELIN,M.WISNIEWSKA,AUTH 8 J.WEIGELT,P.NORDLUND,M.WIKSTROMTITL THE ISOMERASE DOMAIN OF HUMAN GFPT1 IN COMPLEXTITL 2 WITH FRUCTOSE 6-PHOSPHATEREF TO BE PUBLISHEDREFN Variant […]
General Structure Information 3qxm GRIK2 crystal structure of human gluk2 ligand-binding core in complex with novel marine-derived toxins, neodysiherbaine a 1.65Å AUTH M.UNNO,M.SHINOHARA,K.TAKAYAMA,H.TANAKA,K.TERUYA,K.DOH-URA,AUTH 2 R.SAKAI,M.SASAKI,M.IKEDA-SAITOTITL BINDING AND SELECTIVITY OF THE MARINE TOXIN NEODYSIHERBAINETITL 2 A AND ITS SYNTHETIC ANALOGUES TO GLUK1 AND GLUK2 KAINATETITL 3 RECEPTORS.REF J.MOL.BIOL. V. 413 667 2011REFN ISSN 0022-2836PMID 21893069DOI 10.1016/J.JMB.2011.08.043 […]
General Structure Information 3pdf CTSC discovery of novel cyanamide-based inhibitors of cathepsin c 1.85Å AUTH D.LAINE,M.PALOVICH,P.MCCLELAND,E.PETITJEAN,I.DELHOM,H.XIE,AUTH 2 J.DENG,G.LIN,R.DAVIS,A.JOLIT,N.NEVINS,J.VILLA,J.SCHNECKTITL DISCOVERY OF NOVEL CYANAMIDE-BASED INHIBITORS OF CATHEPSIN CREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2pfi CLCNKA crystal structure of the cytoplasmic domain of the human chloride channel clc-ka 1.6Å AUTH S.MARKOVIC,R.DUTZLERTITL THE STRUCTURE OF THE CYTOPLASMIC DOMAIN OF THETITL 2 CHLORIDE CHANNEL CLC-KA REVEALS A CONSERVEDTITL 3 INTERACTION INTERFACE.REF STRUCTURE V. 15 715 2007REFN ISSN 0969-2126PMID 17562318DOI 10.1016/J.STR.2007.04.013 Variant Set Distributions Mapped Variants
General Structure Information 1t77 LRBA crystal structure of the ph-beach domains of human lrba/bgl 2.4Å AUTH D.GEBAUER,J.LI,G.JOGL,Y.SHEN,D.G.MYSZKA,L.TONGTITL CRYSTAL STRUCTURE OF THE PH-BEACH DOMAINS OF HUMANTITL 2 LRBA/BGLREF BIOCHEMISTRY V. 43 14873 2004REFN ISSN 0006-2960PMID 15554694DOI 10.1021/BI049498Y Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1gh7 CSF2RB crystal structure of the complete extracellular domain of the beta- common receptor of il-3, il-5, and gm-csf 3.0Å AUTH P.D.CARR,S.E.GUSTIN,A.P.CHURCH,J.M.MURPHY,S.C.FORD,D.A.MANN,AUTH 2 D.M.WOLTRING,I.WALKER,D.L.OLLIS,I.G.YOUNGTITL STRUCTURE OF THE COMPLETE EXTRACELLULAR DOMAIN OF THE COMMONTITL 2 BETA SUBUNIT OF THE HUMAN GM-CSF, IL-3, AND IL-5 RECEPTORSTITL 3 REVEALS A NOVEL DIMER CONFIGURATION.REF CELL(CAMBRIDGE,MASS.) V. […]
General Structure Information 1yo8 THBS2 structure of the c-terminal domain of human thrombospondin-2 2.6Å AUTH C.B.CARLSON,D.A.BERNSTEIN,D.S.ANNIS,T.M.MISENHEIMER,AUTH 2 B.L.HANNAH,D.F.MOSHER,J.L.KECKTITL STRUCTURE OF THE CALCIUM-RICH SIGNATURE DOMAIN OF HUMANTITL 2 THROMBOSPONDIN-2REF NAT.STRUCT.MOL.BIOL. V. 12 910 2005REFN ISSN 1545-9993PMID 16186819DOI 10.1038/NSMB997 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants