Assessment of Structural Intolerance and Durability
General Structure Information 2dk3 HECTD1 solution structure of mib-herc2 domain in hect domain containing protein 1 -1.0Å AUTH F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF MIB-HERC2 DOMAIN IN HECTTITL 2 DOMAIN CONTAINING PROTEIN 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2kn6 PYCARD structure of full-length human asc (apoptosis-associated speck-like protein containing a card) -1.0Å AUTH E.DE ALBATITL STRUCTURE AND INTERDOMAIN DYNAMICS OF APOPTOSIS-ASSOCIATEDTITL 2 SPECK-LIKE PROTEIN CONTAINING A CARD (ASC)REF J.BIOL.CHEM. V. 284 32932 2009REFN ISSN 0021-9258PMID 19759015DOI 10.1074/JBC.M109.024273 Variant Set Distributions Mapped Variants
General Structure Information 2cq1 PTBP2 solution structure of rna binding domain in ptb-like protein l -1.0Å AUTH K.TSUDA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF RNA BINDING DOMAIN INTITL 2 PTB-LIKE PROTEIN LREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3vro CBLC crystal structure of the tyrosine kinase binding domain of cbl-c in complex with phospho-src peptide 1.8Å AUTH K.TAKESHITA,T.TEZUKA,Y.ISOZAKI,E.YAMASHITA,M.SUZUKI,M.KIM,AUTH 2 Y.YAMANASHI,T.YAMAMOTO,A.NAKAGAWATITL STRUCTURAL FLEXIBILITY REGULATES PHOSPHOPEPTIDE-BINDINGTITL 2 ACTIVITY OF THE TYROSINE KINASE BINDING DOMAIN OF CBL-C.REF J.BIOCHEM. V. 152 487 2012REFN ISSN 0021-924XPMID 22888118DOI 10.1093/JB/MVS085 Variant Set Distributions Mapped Variants
General Structure Information 3pfs BRPF3 pwwp domain of human bromodomain and phd finger-containing protein 3 1.9Å AUTH H.WU,H.ZENG,R.LAM,W.TEMPEL,M.F.AMAYA,C.XU,L.DOMBROVSKI,AUTH 2 W.QIU,Y.WANG,J.MINTITL STRUCTURAL AND HISTONE BINDING ABILITY CHARACTERIZATIONS OFTITL 2 HUMAN PWWP DOMAINS.REF PLOS ONE V. 6 18919 2011REFN ESSN 1932-6203PMID 21720545DOI 10.1371/JOURNAL.PONE.0018919 Variant Set Distributions Mapped Variants
General Structure Information 1wjp ZBTB21 solution structure of zf-c2h2 domains from human zinc finger protein 295 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,K.SAITO,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF ZF-C2H2 DOMAINS FROM HUMANTITL 2 ZINC FINGER PROTEIN 295REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2daw RWDD2A solution structure of the rwd domain of human rwd omain containing protein 2 -1.0Å AUTH M.YONEYAMA,T.KIGAWA,M.SATO,N.TOCHIO,S.KOSHIBA,AUTH 2 M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RWD DOMAIN OF HUMAN RWDTITL 2 OMAIN CONTAINING PROTEIN 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dzm FAF1 solution structure of the ubiquitin-like domain in human fas-associated factor 1 (hfaf1) -1.0Å AUTH C.ZHAO,M.SATO,S.KOSHIBA,S.WATANABE,T.HARADA,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE UBIQUITIN-LIKE DOMAIN INTITL 2 HUMAN FAS-ASSOCIATED FACTOR 1 (HFAF1)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ec1 NUP50 solution structure of the ranbd1 domain from human nucleoporin 50 kda -1.0Å AUTH H.P.ZHANG,C.KUROSAKI,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RANBD1 DOMAIN FROM HUMANTITL 2 NUCLEOPORIN 50 KDAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wi1 CADPS solution structure of the ph domain of human calcium- dependent activator protein for secretion (caps) -1.0Å AUTH M.YONEYAMA,K.IZUMI,M.YOSHIDA,N.TOCHIO,S.KOSHIBA,AUTH 2 M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PH DOMAIN OF HUMANTITL 2 CALCIUM-DEPENDENT ACTIVATOR PROTEIN FOR SECRETIONTITL 3 (CAPS)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants