Assessment of Structural Intolerance and Durability
General Structure Information 1jo6 KCNMB2 solution structure of the cytoplasmic n-terminus of the bk beta-subunit kcnmb2 -1.0Å AUTH D.BENTROP,M.BEYERMANN,R.WISSMANN,B.FAKLERTITL NMR STRUCTURE OF THE BALL-AND-CHAIN DOMAIN OFTITL 2 KCNMB2, THE BETA 2-SUBUNIT OF LARGE CONDUCTANCETITL 3 CA2+- AND VOLTAGE-ACTIVATED POTASSIUM CHANNELS.REF J.BIOL.CHEM. V. 276 42116 2001REFN ISSN 0021-9258PMID 11517232DOI 10.1074/JBC.M107118200 Variant Set Distributions Mapped Variants
General Structure Information 1w24 VPS29 crystal structure of human vps29 2.1Å AUTH D.WANG,M.GUO,Z.LIANG,J.FAN,Z.ZHU,J.ZANG,Z.ZHU,X.LI,AUTH 2 M.TENG,L.NIU,Y.DONG,P.LIUTITL CRYSTAL STRUCTURE OF HUMAN VACUOLAR PROTEINTITL 2 SORTING PROTEIN 29 REVEALS ATITL 3 PHOSPHODIESTERASE/NUCLEASE-LIKE FOLD AND TWOTITL 4 PROTEIN-PROTEIN INTERACTION SITES.REF J.BIOL.CHEM. V. 280 22962 2005REFN ISSN 0021-9258PMID 15788412DOI 10.1074/JBC.M500464200 Variant Set Distributions Mapped Variants
General Structure Information 1uhp PDZRN3 solution structure of rsgi ruh-005, a pdz domain in human cdna, kiaa1095 -1.0Å AUTH T.HAMADA,Y.MUTO,H.HIROTA,S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-005, A PDZ DOMAINTITL 2 IN HUMAN CDNA, KIAA1095REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3haj PACSIN2 crystal structure of human pacsin2 f-bar domain (p212121 lattice) 2.78Å AUTH Q.WANG,M.V.NAVARRO,G.PENG,E.MOLINELLI,S.LIN GOH,AUTH 2 B.L.JUDSON,K.R.RAJASHANKAR,H.SONDERMANNTITL MOLECULAR MECHANISM OF MEMBRANE CONSTRICTION ANDTITL 2 TUBULATION MEDIATED BY THE F-BAR PROTEINTITL 3 PACSIN/SYNDAPIN.REF PROC.NATL.ACAD.SCI.USA V. 106 12700 2009REFN ISSN 0027-8424PMID 19549836DOI 10.1073/PNAS.0902974106 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 3jyh DPP7 human dipeptidyl peptidase dpp7 2.19Å AUTH E.DOBROVETSKY,A.DONG,A.SEITOVA,L.CROMBETT,S.PAGANON,AUTH 2 D.COSSAR,A.M.EDWARDS,C.H.ARROWSMITH,C.BOUNTRA,J.WEIGELT,AUTH 3 A.HASSEL,L.SHEWCHUK,A.BOCHKAREVTITL HUMAN DIPEPTIDYL PEPTIDASE DPP7REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2v8s VTI1B vti1b habc domain – epsinr enth domain complex 2.22Å AUTH S.E.MILLER,B.M.COLLINS,A.J.MCCOY,M.S.ROBINSON,AUTH 2 D.J.OWENTITL A SNARE-ADAPTOR INTERACTION IS A NEW MODE OF CARGOTITL 2 RECOGNITION IN CLATHRIN COATED VESICLESREF NATURE V. 450 570 2007REFN ISSN 0028-0836PMID 18033301DOI 10.1038/NATURE06353 Variant Set Distributions Mapped Variants
General Structure Information 3f6k SORT1 crystal structure of the vps10p domain of human sortilin/nts3 in complex with neurotensin 2.0Å AUTH E.M.QUISTGAARD,P.MADSEN,M.K.GROFTEHAUGE,P.NISSEN,AUTH 2 C.M.PETERSEN,S.S.THIRUPTITL LIGANDS BIND TO SORTILIN IN THE TUNNEL OF A TEN-BLADEDTITL 2 BETA-PROPELLER DOMAIN.REF NAT.STRUCT.MOL.BIOL. V. 16 96 2009REFN ISSN 1545-9993PMID 19122660DOI 10.1038/NSMB.1543 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 4f7h FERMT2 the crystal structure of kindlin-2 pleckstrin homology domain in free form 1.9Å AUTH Y.LIU,Y.ZHU,S.YE,R.ZHANGTITL CRYSTAL STRUCTURE OF KINDLIN-2 PH DOMAIN REVEALS ATITL 2 CONFORMATIONAL TRANSITION FOR ITS MEMBRANE ANCHORING ANDTITL 3 REGULATION OF INTEGRIN ACTIVATION.REF PROTEIN CELL V. 3 434 2012REFN ISSN 1674-800XPMID 22653426DOI 10.1007/S13238-012-2046-1 Variant Set Distributions Mapped Variants
General Structure Information 3fdw SYTL4 crystal structure of a c2 domain from human synaptotagmin- like protein 4 2.2Å AUTH J.B.BONANNO,M.RUTTER,K.T.BAIN,S.MILLER,R.ROMERO,AUTH 2 S.WASSERMAN,J.M.SAUDER,S.K.BURLEY,S.C.ALMOTITL CRYSTAL STRUCTURE OF A C2 DOMAIN FROM HUMANTITL 2 SYNAPTOTAGMIN-LIKE PROTEIN 4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3eu9 ZDHHC17 the ankyrin repeat domain of huntingtin interacting protein 14 1.99Å AUTH T.GAO,R.E.COLLINS,J.R.HORTON,X.ZHANG,R.ZHANG,A.DHAYALAN,AUTH 2 R.TAMAS,A.JELTSCH,X.CHENGTITL THE ANKYRIN REPEAT DOMAIN OF HUNTINGTIN INTERACTING PROTEINTITL 2 14 CONTAINS A SURFACE AROMATIC CAGE, A POTENTIAL SITE FORTITL 3 METHYL-LYSINE BINDING.REF PROTEINS V. 76 772 2009REFN ISSN 0887-3585PMID 19434754DOI 10.1002/PROT.22452 Variant Set Distributions Mapped Variants