Assessment of Structural Intolerance and Durability
General Structure Information 3pb9 QPCTL crystal structure of the catalytic domain of human golgi-resident glutaminyl cyclase in complex with 1-benzylimidazole 1.12Å AUTH K.F.HUANG,S.S.LIAW,W.L.HUANG,C.Y.CHIA,Y.C.LO,Y.L.CHEN,AUTH 2 A.H.J.WANGTITL STRUCTURES OF HUMAN GOLGI-RESIDENT GLUTAMINYL CYCLASE ANDTITL 2 ITS COMPLEXES WITH INHIBITORS REVEAL A LARGE LOOP MOVEMENTTITL 3 UPON INHIBITOR BINDINGREF J.BIOL.CHEM. V. 286 12439 2011REFN ISSN 0021-9258PMID 21288892DOI 10.1074/JBC.M110.208595 […]
General Structure Information 1k8f CAP1 crystal structure of the human c-terminal cap1-adenylyl cyclase associated protein 2.8Å AUTH T.DODATKO,A.A.FEDOROV,M.GRYNBERG,Y.PATSKOVSKY,D.A.ROZWARSKI,AUTH 2 L.JAROSZEWSKI,E.ARONOFF-SPENCER,E.KONDRASKINA,T.IRVING,AUTH 3 A.GODZIK,S.C.ALMOTITL CRYSTAL STRUCTURE OF THE ACTIN BINDING DOMAIN OF THETITL 2 CYCLASE-ASSOCIATED PROTEIN.REF BIOCHEMISTRY V. 43 10628 2004REFN ISSN 0006-2960PMID 15311924DOI 10.1021/BI049071R Variant Set Distributions Mapped Variants
General Structure Information 1k8f CAP1 crystal structure of the human c-terminal cap1-adenylyl cyclase associated protein 2.8Å AUTH T.DODATKO,A.A.FEDOROV,M.GRYNBERG,Y.PATSKOVSKY,D.A.ROZWARSKI,AUTH 2 L.JAROSZEWSKI,E.ARONOFF-SPENCER,E.KONDRASKINA,T.IRVING,AUTH 3 A.GODZIK,S.C.ALMOTITL CRYSTAL STRUCTURE OF THE ACTIN BINDING DOMAIN OF THETITL 2 CYCLASE-ASSOCIATED PROTEIN.REF BIOCHEMISTRY V. 43 10628 2004REFN ISSN 0006-2960PMID 15311924DOI 10.1021/BI049071R Variant Set Distributions Mapped Variants
General Structure Information 1k8f CAP1 crystal structure of the human c-terminal cap1-adenylyl cyclase associated protein 2.8Å AUTH T.DODATKO,A.A.FEDOROV,M.GRYNBERG,Y.PATSKOVSKY,D.A.ROZWARSKI,AUTH 2 L.JAROSZEWSKI,E.ARONOFF-SPENCER,E.KONDRASKINA,T.IRVING,AUTH 3 A.GODZIK,S.C.ALMOTITL CRYSTAL STRUCTURE OF THE ACTIN BINDING DOMAIN OF THETITL 2 CYCLASE-ASSOCIATED PROTEIN.REF BIOCHEMISTRY V. 43 10628 2004REFN ISSN 0006-2960PMID 15311924DOI 10.1021/BI049071R Variant Set Distributions Mapped Variants
General Structure Information 1ism BST1 crystal structure analysis of bst-1/cd157 complexed with nicotinamide 3.0Å AUTH S.YAMAMOTO-KATAYAMA,M.ARIYOSHI,K.ISHIHARA,T.HIRANO,AUTH 2 H.JINGAMI,K.MORIKAWATITL CRYSTALLOGRAPHIC STUDIES ON HUMAN BST-1/CD157 WITHTITL 2 ADP-RIBOSYL CYCLASE AND NAD GLYCOHYDROLASE ACTIVITIES.REF J.MOL.BIOL. V. 316 711 2002REFN ISSN 0022-2836PMID 11866528DOI 10.1006/JMBI.2001.5386 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2wz1 GUCY1B3 structure of the catalytic domain of human soluble guanylate cyclase 1 beta 3. 1.63Å AUTH C.K.ALLERSTON,F.VON DELFT,O.GILEADITITL CRYSTAL STRUCTURES OF THE CATALYTIC DOMAIN OF HUMAN SOLUBLETITL 2 GUANYLATE CYCLASE.REF PLOS ONE V. 8 57644 2013REFN ISSN 1932-6203PMID 23505436DOI 10.1371/JOURNAL.PONE.0057644 Variant Set Distributions Mapped Variants
General Structure Information 1k93 CALM3 crystal structure of the adenylyl cyclase domain of anthrax edema factor (ef) in complex with calmodulin 2.95Å AUTH C.L.DRUM,S.-Z.YAN,J.BARD,Y.-Q.SHEN,D.LU,AUTH 2 S.SOELAIMAN,Z.GRABAREK,A.BOHM,W.-J.TANGTITL STRUCTURAL BASIS FOR THE ACTIVATION OF ANTHRAXTITL 2 ADENYLYL CYCLASE EXOTOXIN BY CALMODULIN.REF NATURE V. 415 396 2002REFN ISSN 0028-0836PMID 11807546DOI 10.1038/415396A Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 1k93 CALM2 crystal structure of the adenylyl cyclase domain of anthrax edema factor (ef) in complex with calmodulin 2.95Å AUTH C.L.DRUM,S.-Z.YAN,J.BARD,Y.-Q.SHEN,D.LU,AUTH 2 S.SOELAIMAN,Z.GRABAREK,A.BOHM,W.-J.TANGTITL STRUCTURAL BASIS FOR THE ACTIVATION OF ANTHRAXTITL 2 ADENYLYL CYCLASE EXOTOXIN BY CALMODULIN.REF NATURE V. 415 396 2002REFN ISSN 0028-0836PMID 11807546DOI 10.1038/415396A Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 1k93 CALM1 crystal structure of the adenylyl cyclase domain of anthrax edema factor (ef) in complex with calmodulin 2.95Å AUTH C.L.DRUM,S.-Z.YAN,J.BARD,Y.-Q.SHEN,D.LU,AUTH 2 S.SOELAIMAN,Z.GRABAREK,A.BOHM,W.-J.TANGTITL STRUCTURAL BASIS FOR THE ACTIVATION OF ANTHRAXTITL 2 ADENYLYL CYCLASE EXOTOXIN BY CALMODULIN.REF NATURE V. 415 396 2002REFN ISSN 0028-0836PMID 11807546DOI 10.1038/415396A Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 2wz1 GUCY1B3 structure of the catalytic domain of human soluble guanylate cyclase 1 beta 3. 1.63Å AUTH C.K.ALLERSTON,F.VON DELFT,O.GILEADITITL CRYSTAL STRUCTURES OF THE CATALYTIC DOMAIN OF HUMAN SOLUBLETITL 2 GUANYLATE CYCLASE.REF PLOS ONE V. 8 57644 2013REFN ISSN 1932-6203PMID 23505436DOI 10.1371/JOURNAL.PONE.0057644 Variant Set Distributions Mapped Variants