General Structure Information 3ii6 LIG4 structure of human xrcc4 in complex with the tandem brct domains of dna ligaseiv. 2.4Å AUTH P.Y.WU,P.FRIT,S.MEESALA,S.DAUVILLIER,M.MODESTI,AUTH 2 S.N.ANDRES,Y.HUANG,J.SEKIGUCHI,P.CALSOU,B.SALLES,AUTH 3 M.S.JUNOPTITL STRUCTURAL AND FUNCTIONAL INTERACTION BETWEEN THETITL 2 HUMAN DNA REPAIR PROTEINS DNA LIGASE IV AND XRCC4REF MOL.CELL.BIOL. V. 11 3163 2009REFN ISSN 0270-7306PMID 19332554 Variant Set Distributions Ripley’s K […]
General Structure Information 2grr RANGAP1 crystal structure of human rangap1-ubc9-d127s 1.3Å AUTH A.A.YUNUS,C.D.LIMATITL LYSINE ACTIVATION AND FUNCTIONAL ANALYSIS OFTITL 2 E2-MEDIATED CONJUGATION IN THE SUMO PATHWAY.REF NAT.STRUCT.MOL.BIOL. V. 13 491 2006REFN ISSN 1545-9993PMID 16732283DOI 10.1038/NSMB1104 Variant Set Distributions Mapped Variants
General Structure Information 2a9u USP8 structure of the n-terminal domain of human ubiquitin carboxyl-terminal hydrolase 8 (usp8) 2.1Å AUTH G.V.AVVAKUMOV,J.R.WALKER,S.XUE,P.J.FINERTY JR.,AUTH 2 F.MACKENZIE,E.M.NEWMAN,S.DHE-PAGANONTITL AMINO-TERMINAL DIMERIZATION, NRDP1-RHODANESETITL 2 INTERACTION, AND INHIBITED CATALYTIC DOMAINTITL 3 CONFORMATION OF THE UBIQUITIN-SPECIFIC PROTEASE 8TITL 4 (USP8).REF J.BIOL.CHEM. V. 281 38061 2006REFN ISSN 0021-9258PMID 17035239DOI 10.1074/JBC.M606704200 Variant Set Distributions Mapped Variants
General Structure Information 3ihp USP5 covalent ubiquitin-usp5 complex 2.8Å AUTH J.R.WALKER,G.V.AVVAKUMOV,S.XUE,C.BUTLER-COLE,AUTH 2 J.WEIGELT,C.BOUNTRA,C.H.ARROWSMITH,A.M.EDWARDS,AUTH 3 A.BOCHKAREV,S.DHE-PAGANONTITL COVALENT UBIQUITIN-USP5 COMPLEXREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3n3k USP8 the catalytic domain of usp8 in complex with a usp8 specific inhibitor 2.6Å AUTH A.ERNST,G.AVVAKUMOV,J.TONG,Y.FAN,Y.ZHAO,P.ALBERTS,A.PERSAUD,AUTH 2 J.R.WALKER,A.M.NECULAI,D.NECULAI,A.VOROBYOV,P.GARG,L.BEATTY,AUTH 3 P.K.CHAN,Y.C.JUANG,M.C.LANDRY,C.YEH,E.ZEQIRAJ,K.KARAMBOULAS,AUTH 4 A.ALLALI-HASSANI,M.VEDADI,M.TYERS,J.MOFFAT,F.SICHERI,AUTH 5 L.PELLETIER,D.DUROCHER,B.RAUGHT,D.ROTIN,J.YANG,M.F.MORAN,AUTH 6 S.DHE-PAGANON,S.S.SIDHUTITL A STRATEGY FOR MODULATION OF ENZYMES IN THE UBIQUITINTITL 2 SYSTEM.REF SCIENCE V. 339 590 2013REFN ISSN 0036-8075PMID 23287719DOI 10.1126/SCIENCE.1230161 Variant Set Distributions Ripley’s K […]
General Structure Information 2gwf USP8 structure of a usp8-nrdp1 complex 2.3Å AUTH G.V.AVVAKUMOV,J.R.WALKER,S.XUE,P.J.FINERTY JR.,F.MACKENZIE,AUTH 2 E.M.NEWMAN,S.DHE-PAGANONTITL AMINO-TERMINAL DIMERIZATION, NRDP1-RHODANESE INTERACTION,TITL 2 AND INHIBITED CATALYTIC DOMAIN CONFORMATION OF THETITL 3 UBIQUITIN-SPECIFIC PROTEASE 8 (USP8).REF J.BIOL.CHEM. V. 281 38061 2006REFN ISSN 0021-9258PMID 17035239DOI 10.1074/JBC.M606704200 Variant Set Distributions Mapped Variants
General Structure Information 3gtu GSTM3 ligand-free heterodimeric human glutathione s-transferase m2-3 (ec 2.5.1.18), monoclinic crystal form 2.8Å AUTH Y.V.PATSKOVSKY,L.N.PATSKOVSKA,I.LISTOWSKYTITL AN ASPARAGINE-PHENYLALANINE SUBSTITUTION ACCOUNTSTITL 2 FOR CATALYTIC DIFFERENCES BETWEEN HGSTM3-3 ANDTITL 3 OTHER HUMAN CLASS MU GLUTATHIONE S-TRANSFERASES.REF BIOCHEMISTRY V. 38 16187 1999REFN ISSN 0006-2960PMID 10587441DOI 10.1021/BI991714T Variant Set Distributions Mapped Variants
General Structure Information 2f3m GSTM1 structure of human glutathione s-transferase m1a-1a complexed with 1-(s-(glutathionyl)-2,4,6- trinitrocyclohexadienate anion 2.7Å AUTH Y.PATSKOVSKY,L.PATSKOVSKA,S.C.ALMO,I.LISTOWSKYTITL TRANSITION STATE MODEL AND MECHANISM OFTITL 2 NUCLEOPHILIC AROMATIC SUBSTITUTION REACTIONSTITL 3 CATALYZED BY HUMAN GLUTATHIONE S-TRANSFERASETITL 4 M1A-1A.REF BIOCHEMISTRY V. 45 3852 2006REFN ISSN 0006-2960PMID 16548513DOI 10.1021/BI051823+ Variant Set Distributions Mapped Variants