Assessment of Structural Intolerance and Durability
General Structure Information 3dpe MMP8 crystal structure of the complex between mmp-8 and a non- zinc chelating inhibitor 1.6Å AUTH G.POCHETTI,R.MONTANARI,C.GEGE,C.CHEVRIER,AUTH 2 A.G.TAVERAS,F.MAZZATITL EXTRA BINDING REGION INDUCED BY NON-ZINC CHELATINGTITL 2 INHIBITORS INTO THE S(1) SUBSITE OF MATRIXTITL 3 METALLOPROTEINASE 8 (MMP-8)REF J.MED.CHEM. V. 52 1040 2009REFN ISSN 0022-2623PMID 19173605DOI 10.1021/JM801166J Variant Set Distributions Ripley’s […]
General Structure Information 2okn PEPD crystal strcture of human prolidase 2.45Å AUTH U.MUELLER,F.H.NIESEN,Y.ROSKE,F.GOETZ,J.BEHLKE,K.BUESSOW,AUTH 2 U.HEINEMANNTITL CRYSTAL STRUCTURE OF HUMAN PROLIDASE: THE MOLECULAR BASIS OFTITL 2 PD DISEASE.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1slm MMP3 crystal structure of fibroblast stromelysin-1: the c-truncated human proenzyme 1.9Å AUTH J.W.BECKER,A.I.MARCY,L.L.ROKOSZ,M.G.AXEL,J.J.BURBAUM,AUTH 2 P.M.FITZGERALD,P.M.CAMERON,C.K.ESSER,W.K.HAGMANN,J.D.HERMES,AUTH 3 J.P.SPRINGERTITL STROMELYSIN-1: THREE-DIMENSIONAL STRUCTURE OF THE INHIBITEDTITL 2 CATALYTIC DOMAIN AND OF THE C-TRUNCATED PROENZYME.REF PROTEIN SCI. V. 4 1966 1995REFN ISSN 0961-8368PMID 8535233 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 1gxd MMP2 prommp-2/timp-2 complex 3.1Å AUTH E.MORGUNOVA,A.TUUTTILA,U.BERGMANN,K.TRYGGVASONTITL STRUCTURAL INSIGHT INTO THE COMPLEX FORMATION OF LATENTTITL 2 MATRIX METALLOPROTEINASE 2 WITH TISSUE INHIBITOR OFTITL 3 METALLOPROTEINASE 2REF PROC.NATL.ACAD.SCI.USA V. 99 7414 2002REFN ISSN 0027-8424PMID 12032297DOI 10.1073/PNAS.102185399 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants