General Structure Information
| PDB ID | 1slm |
| HGNC Gene Label(s) | MMP3 |
| Structure Name | crystal structure of fibroblast stromelysin-1: the c-truncated human proenzyme |
| Resolution | 1.9Å |
| Reference | AUTH J.W.BECKER,A.I.MARCY,L.L.ROKOSZ,M.G.AXEL,J.J.BURBAUM,AUTH 2 P.M.FITZGERALD,P.M.CAMERON,C.K.ESSER,W.K.HAGMANN,J.D.HERMES,AUTH 3 J.P.SPRINGERTITL STROMELYSIN-1: THREE-DIMENSIONAL STRUCTURE OF THE INHIBITEDTITL 2 CATALYTIC DOMAIN AND OF THE C-TRUNCATED PROENZYME.REF PROTEIN SCI. V. 4 1966 1995REFN ISSN 0961-8368PMID 8535233 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 226 |
| Number Of SNVs | 66 |
| Number Of Permutations | 7956 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.038 |
| p-value | 0.861 |
COSMIC
| Number Of Residues | 226 |
| Number Of SNVs | 6 |
| Number Of Permutations | 649 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.067 |
| p-value | 0.664 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 66 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | -0.141 |
| p-value | 0.81 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
