Assessment of Structural Intolerance and Durability
General Structure Information 2knc ITGB3 platelet integrin alfaiib-beta3 transmembrane-cytoplasmic heterocomplex -1.0Å AUTH J.YANG,Y.Q.MA,R.C.PAGE,S.MISRA,E.F.PLOW,J.QINTITL STRUCTURE OF AN INTEGRIN ALPHAIIB BETA3TITL 2 TRANSMEMBRANE-CYTOPLASMIC HETEROCOMPLEX PROVIDES INSIGHTTITL 3 INTO INTEGRIN ACTIVATION.REF PROC.NATL.ACAD.SCI.USA V. 106 17729 2009REFN ISSN 0027-8424PMID 19805198DOI 10.1073/PNAS.0909589106 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2rjp ADAMTS4 crystal structure of adamts4 with inhibitor bound 2.8Å AUTH L.MOSYAK,K.GEORGIADIS,T.SHANE,K.SVENSON,T.HEBERT,AUTH 2 T.MCDONAGH,S.MACKIE,S.OLLAND,L.LIN,X.ZHONG,R.KRIZ,AUTH 3 E.L.REIFENBERG,L.A.COLLINS-RACIE,C.CORCORAN,AUTH 4 B.FREEMAN,R.ZOLLNER,T.MARVELL,M.VERA,P.E.SUM,AUTH 5 E.R.LAVALLIE,M.STAHL,W.SOMERSTITL CRYSTAL STRUCTURES OF THE TWO MAJOR AGGRECANTITL 2 DEGRADING ENZYMES, ADAMTS4 AND ADAMTS5.REF PROTEIN SCI. V. 17 16 2008REFN ISSN 0961-8368PMID 18042673DOI 10.1110/PS.073287008 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 3b4v FSTL3 x-ray structure of activin in complex with fstl3 2.48Å AUTH R.STAMLER,H.T.KEUTMANN,Y.SIDIS,C.KATTAMURI,A.SCHNEYER,AUTH 2 T.B.THOMPSONTITL THE STRUCTURE OF FSTL3.ACTIVIN A COMPLEX. DIFFERENTIALTITL 2 BINDING OF N-TERMINAL DOMAINS INFLUENCES FOLLISTATIN-TYPETITL 3 ANTAGONIST SPECIFICITY.REF J.BIOL.CHEM. V. 283 32831 2008REFN ISSN 0021-9258PMID 18768470DOI 10.1074/JBC.M801266200 Variant Set Distributions Mapped Variants