General Structure Information 2g4c POLG2 crystal structure of human dna polymerase gamma accessory subunit 3.15Å AUTH L.FAN,S.KIM,C.L.FARR,K.T.SCHAEFER,K.M.RANDOLPH,AUTH 2 J.A.TAINER,L.S.KAGUNITITL A NOVEL PROCESSIVE MECHANISM FOR DNA SYNTHESISTITL 2 REVEALED BY STRUCTURE, MODELING AND MUTAGENESIS OFTITL 3 THE ACCESSORY SUBUNIT OF HUMAN MITOCHONDRIAL DNATITL 4 POLYMERASEREF J.MOL.BIOL. V. 358 1229 2006REFN ISSN 0022-2836PMID 16574152DOI 10.1016/J.JMB.2006.02.073 Variant Set […]
General Structure Information 3tgx IL21R il-21:il21r complex 2.8Å AUTH O.J.HAMMING,L.KANG,A.SVENSSON,J.L.KARLSEN,H.RAHBEK-NIELSEN,AUTH 2 S.R.PALUDAN,S.A.HJORTH,K.BONDENSGAARD,R.HARTMANNTITL THE CRYSTAL STRUCTURE OF THE INTERLEUKIN 21 RECEPTOR BOUNDTITL 2 TO INTERLEUKIN 21 REVEALS THAT A SUGAR CHAIN INTERACTINGTITL 3 WITH THE WSXWS MOTIF IS AN INTEGRAL PART OF THE INTERLEUKINTITL 4 21 RECEPTOR.REF J.BIOL.CHEM. 2012REFN ESSN 1083-351XPMID 22235133DOI 10.1074/JBC.M111.311084 Variant Set Distributions […]
General Structure Information 3tgx IL21 il-21:il21r complex 2.8Å AUTH O.J.HAMMING,L.KANG,A.SVENSSON,J.L.KARLSEN,H.RAHBEK-NIELSEN,AUTH 2 S.R.PALUDAN,S.A.HJORTH,K.BONDENSGAARD,R.HARTMANNTITL THE CRYSTAL STRUCTURE OF THE INTERLEUKIN 21 RECEPTOR BOUNDTITL 2 TO INTERLEUKIN 21 REVEALS THAT A SUGAR CHAIN INTERACTINGTITL 3 WITH THE WSXWS MOTIF IS AN INTEGRAL PART OF THE INTERLEUKINTITL 4 21 RECEPTOR.REF J.BIOL.CHEM. 2012REFN ESSN 1083-351XPMID 22235133DOI 10.1074/JBC.M111.311084 Variant Set Distributions […]
General Structure Information 1kcg ULBP3 nkg2d in complex with ulbp3 2.6Å AUTH S.RADAEV,B.ROSTRO,A.G.BROOKS,M.COLONNA,P.D.SUNTITL CONFORMATIONAL PLASTICITY REVEALED BY THETITL 2 COCRYSTAL STRUCTURE OF NKG2D AND ITS CLASS ITITL 3 MHC-LIKE LIGAND ULBP3.REF IMMUNITY V. 15 1039 2001REFN ISSN 1074-7613PMID 11754823DOI 10.1016/S1074-7613(01)00241-2 Variant Set Distributions Mapped Variants
General Structure Information 4m6r APIP structural and biochemical basis for the inhibition of cell death by apip, a methionine salvage enzyme 2.0Å AUTH W.KANG,S.H.HONG,H.M.LEE,N.Y.KIM,Y.C.LIM,L.T.M.LE,B.LIM,AUTH 2 H.C.KIM,T.Y.KIM,H.ASHIDA,A.YOKOTA,S.S.HAH,K.H.CHUN,Y.K.JUNG,AUTH 3 J.K.YANGTITL STRUCTURAL AND BIOCHEMICAL BASIS FOR THE INHIBITION OF CELLTITL 2 DEATH BY APIP, A METHIONINE SALVAGE ENZYME.REF PROC.NATL.ACAD.SCI.USA V. 111 581 2014REFN ISSN 0027-8424PMID 24367089DOI 10.1073/PNAS.1308768111 Variant […]
General Structure Information 2dm4 SORL1 solution structure of the second fn3 domain of human sorla/lr11 -1.0Å AUTH T.NAGASHIMA,C.KUROSAKI,M.YOSHIDA,F.HAYASHI,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND FN3 DOMAIN OFTITL 2 HUMAN SORLA/LR11REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2iag PTGIS crystal structure of human prostacyclin synthase 2.15Å AUTH C.-W.CHIANG,H.-C.YEH,L.-H.WANG,N.-L.CHANTITL CRYSTAL STRUCTURE OF THE HUMAN PROSTACYCLINTITL 2 SYNTHASEREF J.MOL.BIOL. V. 364 266 2006REFN ISSN 0022-2836PMID 17020766DOI 10.1016/J.JMB.2006.09.039 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1de4 HFE hemochromatosis protein hfe complexed with transferrin receptor 2.8Å AUTH M.J.BENNETT,J.A.LEBRON,P.J.BJORKMANTITL CRYSTAL STRUCTURE OF THE HEREDITARY HAEMOCHROMATOSIS PROTEINTITL 2 HFE COMPLEXED WITH TRANSFERRIN RECEPTOR.REF NATURE V. 403 46 2000REFN ISSN 0028-0836PMID 10638746DOI 10.1038/47417 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1j7v IL10RA human il-10 / il-10r1 complex 2.9Å AUTH K.JOSEPHSON,N.J.LOGSDON,M.R.WALTERTITL CRYSTAL STRUCTURE OF THE IL-10/IL-10R1 COMPLEXTITL 2 REVEALS A SHARED RECEPTOR BINDING SITE.REF IMMUNITY V. 15 35 2001REFN ISSN 1074-7613PMID 11485736DOI 10.1016/S1074-7613(01)00169-8 Variant Set Distributions Mapped Variants
General Structure Information 2×57 VIPR2 crystal structure of the extracellular domain of human vasoactive intestinal polypeptide receptor 2 2.1Å AUTH A.C.W.PIKE,A.J.BARR,A.QUIGLEY,N.BURGESS BROWN,A.DE RISO,AUTH 2 A.BULLOCK,G.BERRIDGE,J.R.C.MUNIZ,A.CHAIKAUD,M.VOLLMAR,AUTH 3 T.KROJER,E.UGOCHUKWU,F.VON DELFT,A.EDWARDS,C.H.ARROWSMITH,AUTH 4 J.WEIGELT,C.BOUNTRA,E.P.CARPENTERTITL CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMANTITL 2 VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants