Assessment of Structural Intolerance and Durability
General Structure Information 2cqm MRPL17 solution structure of the mitochondrial ribosomal protein l17 isolog -1.0Å AUTH S.SUZUKI,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE MITOCHONDRIAL RIBOSOMALTITL 2 PROTEIN L17 ISOLOGREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3ux3 FAM96A crystal structure of domain-swapped fam96a minor dimer 1.8Å AUTH K.-E.CHEN,A.A.RICHARDS,J.K.ARIFFIN,I.L.ROSS,M.J.SWEET,AUTH 2 S.KELLIE,B.KOBE,J.L.MARTINTITL THE MAMMALIAN DUF59 PROTEIN FAM96A FORMS TWO DISTINCT TYPESTITL 2 OF DOMAIN-SWAPPED DIMERREF ACTA CRYSTALLOGR.,SECT.D V. 68 637 2012REFN ISSN 0907-4449DOI 10.1107/S0907444912006592 Variant Set Distributions Mapped Variants
General Structure Information 2y9t TP63 structural basis of p63a sam domain mutants involved in aec syndrome -1.0Å AUTH A.SATHYAMURTHY,S.M.V.FREUND,C.M.JOHNSON,M.D.ALLEN,M.BYCROFTTITL STRUCTURAL BASIS OF P63ALPHA SAM DOMAIN MUTANTS INVOLVED INTITL 2 AEC SYNDROME.REF FEBS J. V. 278 2680 2011REFN ISSN 1742-464XPMID 21615690DOI 10.1111/J.1742-4658.2011.08194.X Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2mc3 MUS81 nmr solution structure of the winged-helix domain from mus81 structure-specific endonuclease -1.0Å AUTH A.J.FADDEN,S.SCHALBETTER,M.BOWLES,R.HARRIS,J.LALLY,A.M.CARR,AUTH 2 N.Q.MCDONALDTITL A WINGED HELIX DOMAIN IN HUMAN MUS81 BINDS DNA AND MODULATESTITL 2 THE ENDONUCLEASE ACTIVITY OF MUS81 COMPLEXES.REF NUCLEIC ACIDS RES. V. 41 9741 2013REFN ISSN 0305-1048PMID 23982516DOI 10.1093/NAR/GKT760 Variant Set Distributions Mapped Variants
General Structure Information 3pja TSNAX crystal structure of human c3po complex 3.0Å AUTH X.YE,N.HUANG,Y.LIU,Z.PAROO,C.HUERTA,P.LI,S.CHEN,Q.LIU,AUTH 2 H.ZHANGTITL STRUCTURE OF C3PO AND MECHANISM OF HUMAN RISC ACTIVATION.REF NAT.STRUCT.MOL.BIOL. V. 18 650 2011REFN ISSN 1545-9993PMID 21552258DOI 10.1038/NSMB.2032 Variant Set Distributions Mapped Variants
General Structure Information 2l4m ZBP1 solution structure of the zbeta domain of human dai and its binding modes to b- and z-dna -1.0Å AUTH K.KIM,B.KHAYRUTDINOV,C.-K.LEE,H.-K.CHEONG,S.KANG,H.PARK,AUTH 2 S.LEE,Y.-G.KIM,J.-G.JEE,A.RICH,K.K.KIM,Y.H.JEONTITL SOLUTION STRUCTURE OF THE ZBETA DOMAIN OF HUMANTITL 2 DNA-DEPENDENT ACTIVATOR OF IFN-REGULATORY FACTORS AND ITSTITL 3 BINDING MODES TO B- AND Z-DNAREF PROC.NATL.ACAD.SCI.USA 2011REFN ESSN 1091-6490 Variant […]
General Structure Information 1wyn CNN2 solution structure of the ch domain of human calponin-2 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CH DOMAIN OF HUMANTITL 2 CALPONIN-2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4nac RPRD1A crystal structure of the n-terminal domain of p15rs 2.0Å AUTH K.MEI,Z.JIN,F.REN,Y.WANG,Z.CHANG,X.WANGTITL CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF P15RSREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4dwn C9orf89 crystal structure of human bincard card 1.58Å AUTH K.E.CHEN,A.A.RICHARDS,T.T.CARADOC-DAVIES,P.R.VAJJHALA,AUTH 2 G.ROBIN,L.H.LUA,J.M.HILL,K.SCHRODER,M.J.SWEET,S.KELLIE,AUTH 3 B.KOBE,J.MARTINTITL THE STRUCTURE OF THE CASPASE RECRUITMENT DOMAIN OF BINCARDTITL 2 REVEALS THAT ALL THREE CYSTEINES CAN BE OXIDIZED.REF ACTA CRYSTALLOGR.,SECT.D V. 69 774 2013REFN ISSN 0907-4449PMID 23633586DOI 10.1107/S0907444913001558 Variant Set Distributions Mapped Variants
General Structure Information 4is7 CASKIN2 crystal structure of the caskin2 sam domain tandem 2.75Å AUTH KWAN J.J.,E.SMIRNOVA,V.SARIDAKIS,DONALDSON L.W.TITL CRYSTAL STRUCTURE OF THE CASKIN2 SAM DOMAIN TANDEMREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants