Assessment of Structural Intolerance and Durability
General Structure Information 3rpg RNF2 bmi1/ring1b-ubch5c complex structure 2.65Å AUTH M.L.BENTLEY,J.E.CORN,K.C.DONG,Q.PHUNG,T.K.CHEUNG,A.G.COCHRANTITL RECOGNITION OF UBCH5C AND THE NUCLEOSOME BY THE BMI1/RING1BTITL 2 UBIQUITIN LIGASE COMPLEX.REF EMBO J. V. 30 3285 2011REFN ISSN 0261-4189PMID 21772249DOI 10.1038/EMBOJ.2011.243 Variant Set Distributions Mapped Variants
General Structure Information 2m0c ALX4 solution nmr structure of homeobox domain of human alx4, northeast structural genomics consortium (nesg) target hr4490c -1.0Å AUTH X.XU,A.ELETSKY,S.PULAVARTI,D.LEE,H.JANJUA,R.XIAO,T.B.ACTON,AUTH 2 J.K.EVERETT,G.T.MONTELIONE,T.SZYPERSKITITL SOLUTION NMR STRUCTURE OF HOMEOBOX DOMAIN OF HUMAN ALX4,TITL 2 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGETTITL 3 HR4490CREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 2dnk CELF4 solution structure of rna binding domain in bruno-like 4 rna binding protein -1.0Å AUTH K.TSUDA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF RNA BINDING DOMAIN INTITL 2 BRUNO-LIKE 4 RNA BINDING PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2de0 FUT8 crystal structure of human alpha 1,6-fucosyltransferase, fut8 2.61Å AUTH H.IHARA,Y.IKEDA,S.TOMA,X.WANG,T.SUZUKI,J.GU,E.MIYOSHI,AUTH 2 T.TSUKIHARA,K.HONKE,A.MATSUMOTO,A.NAKAGAWA,N.TANIGUCHITITL CRYSTAL STRUCTURE OF MAMMALIANTITL 2 {ALPHA}1,6-FUCOSYLTRANSFERASE, FUT8REF GLYCOBIOLOGY V. 17 455 2007REFN ISSN 0959-6658PMID 17172260DOI 10.1093/GLYCOB/CWL079 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3zjb TRAF4 the structure of the traf domain of human traf4 1.84Å AUTH A.ROUSSEAU,A.G.MCEWEN,P.POUSSIN-COURMONTAGNE,D.ROGNAN,AUTH 2 Y.NOMINE,M.-C.RIO,C.TOMASETTO,F.ALPYTITL TRAF4 IS A NOVEL PHOSPHOINOSITIDE-BINDING PROTEINTITL 2 MODULATING TIGHT JUNCTIONS AND FAVORING CELL MIGRATION.REF PLOS BIOL. V. 11 1726 2013REFN ISSN 1544-9173PMID 24311986DOI 10.1371/JOURNAL.PBIO.1001726 Variant Set Distributions Mapped Variants
General Structure Information 1udw UCK2 crystal structure of human uridine-cytidine kinase 2 complexed with a feedback-inhibitor, ctp 2.6Å AUTH N.N.SUZUKI,K.KOIZUMI,M.FUKUSHIMA,A.MATSUDA,AUTH 2 F.INAGAKITITL STRUCTURAL BASIS FOR THE SPECIFICITY, CATALYSIS,TITL 2 AND REGULATION OF HUMAN URIDINE-CYTIDINE KINASEREF STRUCTURE V. 12 751 2004REFN ISSN 0969-2126PMID 15130468DOI 10.1016/J.STR.2004.02.038 Variant Set Distributions Mapped Variants
General Structure Information 4bie MAP3K5 crystal structures of ask1-inhibitor complexes 2.36Å AUTH O.SINGH,A.SHILLINGS,P.CRAGGS,I.WALL,P.ROWLAND,T.SKARZYNSKI,AUTH 2 C.I.HOBBS,P.HARDWICK,R.TANNER,M.BLUNT,D.R.WITTY,K.J.SMITHTITL CRYSTAL STRUCTURES OF ASK1-INHIBTOR COMPLEXES PROVIDE ATITL 2 PLATFORM FOR STRUCTURE BASED DRUG DESIGN.REF PROTEIN SCI. V. 22 1071 2013REFN ISSN 0961-8368PMID 23776076DOI 10.1002/PRO.2298 Variant Set Distributions Mapped Variants
General Structure Information 3sd4 PHF20 crystal structure of the first tudor domain of human phf20 1.93Å AUTH G.CUI,S.PARK,A.I.BADEAUX,D.KIM,J.LEE,J.R.THOMPSON,F.YAN,AUTH 2 S.KANEKO,Z.YUAN,M.V.BOTUYAN,M.T.BEDFORD,J.Q.CHENG,G.MERTITL PHF20 IS AN EFFECTOR PROTEIN OF P53 DOUBLE LYSINETITL 2 METHYLATION THAT STABILIZES AND ACTIVATES P53.REF NAT.STRUCT.MOL.BIOL. V. 19 916 2012REFN ISSN 1545-9993PMID 22864287DOI 10.1038/NSMB.2353 Variant Set Distributions Mapped Variants
General Structure Information 2kk0 ARID3A solution structure of dead ringer-like protein 1 (at-rich interactive domain-containing protein 3a) from homo sapiens, northeast structural genomics consortium (nesg) target hr4394c -1.0Å AUTH G.LIU,Y.J.HUANG,R.XIAO,D.WANG,T.B.ACTON,G.T.MONTELIONETITL SOLUTION NMR STRUCTURE OF THE ARID DOMAIN OF HUMAN AT-RICHTITL 2 INTERACTIVE DOMAIN-CONTAINING PROTEIN 3A: A HUMAN CANCERTITL 3 PROTEIN INTERACTION NETWORK TARGET.REF PROTEINS V. […]
General Structure Information 3bpu MAGI1 crystal structure of the 3rd pdz domain of human membrane associated guanylate kinase, c677s and c709s double mutant 1.6Å AUTH E.S.PILKA,V.HOZJAN,C.COOPER,A.C.W.PIKE,J.ELKINS,D.A.DOYLE,AUTH 2 F.VON DELFT,C.H.ARROWSMITH,A.M.EDWARDS,J.WEIGELT,U.OPPERMANNTITL CRYSTAL STRUCTURE OF THE 3RD PDZ DOMAIN OF HUMAN MEMBRANETITL 2 ASSOCIATED GUANYLATE KINASE, C677S AND C709S DOUBLE MUTANT.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped […]