Assessment of Structural Intolerance and Durability
General Structure Information 2hye CUL4A crystal structure of the ddb1-cul4a-rbx1-sv5v complex 3.1Å AUTH S.ANGERS,T.LI,X.YI,M.J.MACCOSS,R.T.MOON,N.ZHENGTITL MOLECULAR ARCHITECTURE AND ASSEMBLY OF THETITL 2 DDB1-CUL4A UBIQUITIN LIGASE MACHINERY.REF NATURE V. 443 590 2006REFN ISSN 0028-0836PMID 16964240DOI 10.1038/NATURE05175 Variant Set Distributions Mapped Variants
General Structure Information 2hye CUL4A crystal structure of the ddb1-cul4a-rbx1-sv5v complex 3.1Å AUTH S.ANGERS,T.LI,X.YI,M.J.MACCOSS,R.T.MOON,N.ZHENGTITL MOLECULAR ARCHITECTURE AND ASSEMBLY OF THETITL 2 DDB1-CUL4A UBIQUITIN LIGASE MACHINERY.REF NATURE V. 443 590 2006REFN ISSN 0028-0836PMID 16964240DOI 10.1038/NATURE05175 Variant Set Distributions Mapped Variants
General Structure Information 2hye CUL4A crystal structure of the ddb1-cul4a-rbx1-sv5v complex 3.1Å AUTH S.ANGERS,T.LI,X.YI,M.J.MACCOSS,R.T.MOON,N.ZHENGTITL MOLECULAR ARCHITECTURE AND ASSEMBLY OF THETITL 2 DDB1-CUL4A UBIQUITIN LIGASE MACHINERY.REF NATURE V. 443 590 2006REFN ISSN 0028-0836PMID 16964240DOI 10.1038/NATURE05175 Variant Set Distributions Mapped Variants
General Structure Information 3vww PDIA6 crystal structure of a0-domain of p5 from h. sapiens 1.93Å AUTH Y.SATO,R.KOJIMA,M.OKUMURA,M.HAGIWARA,S.MASUI,K.MAEGAWA,AUTH 2 M.SAIKI,T.HORIBE,M.SUZUKI,K.INABATITL SYNERGISTIC COOPERATION OF PDI FAMILY MEMBERS INTITL 2 PEROXIREDOXIN 4-DRIVEN OXIDATIVE PROTEIN FOLDINGREF SCI REP V. 3 2456 2013REFN ESSN 2045-2322PMID 23949117DOI 10.1038/SREP02456 Variant Set Distributions Mapped Variants
General Structure Information 4mjj DOC2A crystal structure of the c2a domain of doc2a 2.0Å AUTH Q.Q.HUANGTITL CRYSTAL STRUCTURE OF THE C2A DOMAIN OF DOC2AREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2cup FHL1 solution structure of the skeletal muscle lim-protein 1 -1.0Å AUTH T.N.NIRAULA,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SKELETAL MUSCLETITL 2 LIM-PROTEIN 1REF TO BE PUBLISHEDREFN Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3e3r CAPS crystal structure and biochemical characterization of recombinant human calcyphosine delineates a novel ef-hand-containing protein family 2.65Å AUTH H.DONG,X.LI,Z.LOU,X.XU,D.SU,X.ZHOU,W.ZHOU,M.BARTLAM,Z.RAOTITL CRYSTAL-STRUCTURE AND BIOCHEMICAL CHARACTERIZATION OFTITL 2 RECOMBINANT HUMAN CALCYPHOSINE DELINEATES A NOVELTITL 3 EF-HAND-CONTAINING PROTEIN FAMILYREF J.MOL.BIOL. V. 383 455 2008REFN ISSN 0022-2836PMID 18775726DOI 10.1016/J.JMB.2008.08.048 Variant Set Distributions Mapped Variants
General Structure Information 2dyb NCF4 the crystal structure of human p40(phox) 3.15Å AUTH K.HONBOU,R.MINAKAMI,S.YUZAWA,R.TAKEYA,N.N.SUZUKI,AUTH 2 S.KAMAKURA,H.SUMIMOTO,F.INAGAKITITL FULL-LENGTH P40PHOX STRUCTURE SUGGESTS A BASIS FORTITL 2 REGULATION MECHANISM OF ITS MEMBRANE BINDING.REF EMBO J. V. 26 1176 2007REFN ISSN 0261-4189PMID 17290225DOI 10.1038/SJ.EMBOJ.7601561 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2coy DCTN1 solution structure of the cap-gly domain in human dynactin 1 -1.0Å AUTH K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CAP-GLY DOMAIN IN HUMANTITL 2 DYNACTIN 1REF TO BE PUBLISHEDREFN Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2coy DCTN1 solution structure of the cap-gly domain in human dynactin 1 -1.0Å AUTH K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CAP-GLY DOMAIN IN HUMANTITL 2 DYNACTIN 1REF TO BE PUBLISHEDREFN Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants