General Structure Information
| PDB ID | 2coy |
| HGNC Gene Label(s) | DCTN1 |
| Structure Name | solution structure of the cap-gly domain in human dynactin 1 |
| Resolution | -1.0Å |
| Reference | AUTH K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CAP-GLY DOMAIN IN HUMANTITL 2 DYNACTIN 1REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 99 |
| Number Of SNVs | 20 |
| Number Of Permutations | 12773 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.363 |
| p-value | 0.806 |
ClinVar
| Number Of Residues | 99 |
| Number Of SNVs | 4 |
| Number Of Permutations | 920 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.833 |
| p-value | 0.022 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 20 |
| Number Of ClinVar SNVs | 4 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.639 |
| p-value | 0.013 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
