Assessment of Structural Intolerance and Durability
General Structure Information 2p2r PCBP2 crystal structure of the third kh domain of human poly(c)- binding protein-2 in complex with c-rich strand of human telomeric dna 1.6Å AUTH S.FENN,Z.DU,J.K.LEE,R.TJHEN,R.M.STROUD,T.L.JAMESTITL CRYSTAL STRUCTURE OF THE THIRD KH DOMAIN OF HUMANTITL 2 POLY(C)-BINDING PROTEIN-2 IN COMPLEX WITH A C-RICHTITL 3 STRAND OF HUMAN TELOMERIC DNA AT 1.6 A […]
General Structure Information 2p2r PCBP2 crystal structure of the third kh domain of human poly(c)- binding protein-2 in complex with c-rich strand of human telomeric dna 1.6Å AUTH S.FENN,Z.DU,J.K.LEE,R.TJHEN,R.M.STROUD,T.L.JAMESTITL CRYSTAL STRUCTURE OF THE THIRD KH DOMAIN OF HUMANTITL 2 POLY(C)-BINDING PROTEIN-2 IN COMPLEX WITH A C-RICHTITL 3 STRAND OF HUMAN TELOMERIC DNA AT 1.6 A […]
General Structure Information 2p2r PCBP2 crystal structure of the third kh domain of human poly(c)- binding protein-2 in complex with c-rich strand of human telomeric dna 1.6Å AUTH S.FENN,Z.DU,J.K.LEE,R.TJHEN,R.M.STROUD,T.L.JAMESTITL CRYSTAL STRUCTURE OF THE THIRD KH DOMAIN OF HUMANTITL 2 POLY(C)-BINDING PROTEIN-2 IN COMPLEX WITH A C-RICHTITL 3 STRAND OF HUMAN TELOMERIC DNA AT 1.6 A […]
General Structure Information 2p2r PCBP2 crystal structure of the third kh domain of human poly(c)- binding protein-2 in complex with c-rich strand of human telomeric dna 1.6Å AUTH S.FENN,Z.DU,J.K.LEE,R.TJHEN,R.M.STROUD,T.L.JAMESTITL CRYSTAL STRUCTURE OF THE THIRD KH DOMAIN OF HUMANTITL 2 POLY(C)-BINDING PROTEIN-2 IN COMPLEX WITH A C-RICHTITL 3 STRAND OF HUMAN TELOMERIC DNA AT 1.6 A […]
General Structure Information 2p2r PCBP2 crystal structure of the third kh domain of human poly(c)- binding protein-2 in complex with c-rich strand of human telomeric dna 1.6Å AUTH S.FENN,Z.DU,J.K.LEE,R.TJHEN,R.M.STROUD,T.L.JAMESTITL CRYSTAL STRUCTURE OF THE THIRD KH DOMAIN OF HUMANTITL 2 POLY(C)-BINDING PROTEIN-2 IN COMPLEX WITH A C-RICHTITL 3 STRAND OF HUMAN TELOMERIC DNA AT 1.6 A […]
General Structure Information 2p2r PCBP2 crystal structure of the third kh domain of human poly(c)- binding protein-2 in complex with c-rich strand of human telomeric dna 1.6Å AUTH S.FENN,Z.DU,J.K.LEE,R.TJHEN,R.M.STROUD,T.L.JAMESTITL CRYSTAL STRUCTURE OF THE THIRD KH DOMAIN OF HUMANTITL 2 POLY(C)-BINDING PROTEIN-2 IN COMPLEX WITH A C-RICHTITL 3 STRAND OF HUMAN TELOMERIC DNA AT 1.6 A […]
General Structure Information 3fzt PTK2B crystal structure of pyk2 complexed with pf-4618433 1.95Å AUTH S.HAN,A.MISTRY,J.S.CHANG,D.CUNNINGHAM,M.GRIFFOR,AUTH 2 P.C.BONNETTE,H.WANG,B.A.CHRUNYK,G.E.ASPNES,AUTH 3 D.P.WALKER,A.D.BROSIUS,L.BUCKBINDERTITL STRUCTURAL CHARACTERIZATION OF PROLINE-RICHTITL 2 TYROSINE KINASE 2 (PYK2) REVEALS A UNIQUE (DFG-OUT)TITL 3 CONFORMATION AND ENABLES INHIBITOR DESIGN.REF J.BIOL.CHEM. V. 284 13193 2009REFN ISSN 0021-9258PMID 19244237DOI 10.1074/JBC.M809038200 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3l15 TEAD2 human tead2 transcriptional factor 2.0Å AUTH W.TIAN,J.YU,D.R.TOMCHICK,D.PAN,X.LUOTITL STRUCTURAL AND FUNCTIONAL ANALYSIS OF THE YAP-BINDINGTITL 2 DOMAIN OF HUMAN TEAD2.REF PROC.NATL.ACAD.SCI.USA V. 107 7293 2010REFN ISSN 0027-8424PMID 20368466DOI 10.1073/PNAS.1000293107 Variant Set Distributions Mapped Variants
General Structure Information 2d7q FLNC solution structure of the 23th filamin domain from human filamin c -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 23TH FILAMIN DOMAIN FROMTITL 2 HUMAN FILAMIN CREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4dpg KARS crystal structure of human lysrs: p38/aimp2 complex i 2.84Å AUTH Y.OFIR-BIRIN,P.FANG,S.P.BENNETT,H.M.ZHANG,J.WANG,I.RACHMIN,AUTH 2 R.SHAPIRO,J.SONG,A.DAGAN,J.POZO,S.KIM,A.G.MARSHALL,AUTH 3 P.SCHIMMEL,X.L.YANG,H.NECHUSHTAN,E.RAZIN,M.GUOTITL STRUCTURAL SWITCH OF LYSYL-TRNA SYNTHETASE BETWEENTITL 2 TRANSLATION AND TRANSCRIPTION.REF MOL.CELL V. 49 30 2013REFN ISSN 1097-2765PMID 23159739DOI 10.1016/J.MOLCEL.2012.10.010 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants