Assessment of Structural Intolerance and Durability
General Structure Information 2y1h TATDN3 crystal structure of the human tatd-domain protein 3 (tatdn3) 2.5Å AUTH J.R.C.MUNIZ,S.PURANIK,T.KROJER,W.W.YUE,E.UGOCHUKWU,AUTH 2 P.FILIPPAKOPOULOS,F.VON DELFT,C.H.ARROWSMITH,A.M.EDWARDS,AUTH 3 J.WEIGELT,C.BOUNTRA,K.L.KAVANAGH,U.OPPERMANNTITL CRYSTAL STRUCTURE OF THE HUMAN TATD-DOMAIN PROTEIN 3TITL 2 (TATDN3)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3soo L1TD1 crystal structure of a line-1 type transposase domain-containing protein 1 (l1td1) from homo sapiens at 2.73 a resolution 2.73Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 2 PARTNERSHIP FOR STEM CELL BIOLOGY (STEMCELL)TITL CRYSTAL STRUCTURE OF A LINE-1 TYPE TRANSPOSASETITL 2 DOMAIN-CONTAINING PROTEIN 1 (L1TD1) FROM HOMO SAPIENS ATTITL 3 […]
General Structure Information 4bq7 RGMB crystal structure of the rgmb-neo1 complex form 2 6.6Å AUTH C.H.BELL,E.HEALEY,S.VAN ERP,B.BISHOP,C.TANG,R.J.C.GILBERT,AUTH 2 A.R.ARICESCU,R.J.PASTERKAMP,C.SIEBOLDTITL STRUCTURE OF THE REPULSIVE GUIDANCE MOLECULE (RGM)-NEOGENINTITL 2 SIGNALING HUBREF SCIENCE V. 341 77 2013REFN ISSN 0036-8075PMID 23744777DOI 10.1126/SCIENCE.1232322 Variant Set Distributions Mapped Variants
General Structure Information 2lpn CDNF solution structure of n-terminal domain of human conserved dopamine neurotrophic factor (cdnf) -1.0Å AUTH C.LATGE,K.M.CABRAL,M.S.ALMEIDA,D.FOGUELTITL (1)H-, (13)C- AND (15)N-NMR ASSIGNMENT OF THE N-TERMINALTITL 2 DOMAIN OF HUMAN CEREBRAL DOPAMINE NEUROTROPHIC FACTORTITL 3 (CDNF).REF BIOMOL.NMR ASSIGN. V. 7 101 2013REFN ISSN 1874-2718PMID 22528768DOI 10.1007/S12104-012-9388-8 Variant Set Distributions Mapped Variants
General Structure Information 4mtl METTL21C human methyltransferase-like protein 21c 1.65Å AUTH B.S.HONG,W.TEMPEL,A.DONG,Y.LI,C.H.ARROWSMITH,C.BOUNTRA,AUTH 2 A.M.EDWARDS,P.J.BROWNTITL HUMAN METHYLTRANSFERASE-LIKE PROTEIN 21CREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3iai CA9 crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase ix 2.2Å AUTH V.ALTERIO,M.HILVO,A.DI FIORE,C.T.SUPURAN,P.PAN,S.PARKKILA,AUTH 2 A.SCALONI,J.PASTOREK,S.PASTOREKOVA,C.PEDONE,A.SCOZZAFAVA,AUTH 3 S.M.MONTI,G.DE SIMONETITL CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THETITL 2 TUMOR-ASSOCIATED HUMAN CARBONIC ANHYDRASE IX.REF PROC.NATL.ACAD.SCI.USA V. 106 16233 2009REFN ISSN 0027-8424PMID 19805286DOI 10.1073/PNAS.0908301106 Variant Set Distributions Mapped Variants
General Structure Information 1uhc DNMBP solution structure of rsgi ruh-002, a sh3 domain of kiaa1010 protein [homo sapiens] -1.0Å AUTH T.ABE,H.HIROTA,N.KOBAYASHI,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-002, A SH3 DOMAINTITL 2 OF KIAA1010 PROTEIN [HOMO SAPIENS]REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2q3h RHOU the crystal structure of rhoua in the gdp-bound state. 1.73Å AUTH C.GILEADI,X.YANG,E.PAPAGRIGORIOU,J.ELKINS,Y.ZHAO,J.BRAY,AUTH 2 O.GILEADI,C.UMEANO,E.UGOCHUKWU,J.UPPENBERG,G.BUNKOCZI,AUTH 3 F.VON DELFT,A.C.W.PIKE,C.PHILLIPS,P.SAVITSKY,O.FEDOROV,AUTH 4 A.EDWARDS,J.WEIGELT,C.H.ARROWSMITH,M.SUNDSTROM,D.A.DOYLETITL THE CRYSTAL STRUCTURE OF RHOUA IN THE GDP-BOUND STATE.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2i7a CAPN13 domain iv of human calpain 13 1.8Å AUTH J.R.WALKER,K.NG,T.L.DAVIS,R.RAVULAPALLI,C.BUTLER-COLE,AUTH 2 P.J.FINERTY JR.,E.M.NEWMAN,J.WEIGELT,M.SUNDSTROM,AUTH 3 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,S.DHE-PAGANONTITL STRUCTURE OF HUMAN CALPAIN 13REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2da1 ZFHX3 solution structure of the first homeobox domain of at- binding transcription factor 1 (atbf1) -1.0Å AUTH S.OHNISHI,T.KIGAWA,T.TOMIZAWA,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST HOMEOBOX DOMAIN OFTITL 2 AT-BINDING TRANSCRIPTION FACTOR 1 (ATBF1)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants