Assessment of Structural Intolerance and Durability
General Structure Information 4l1u RTF1 crystal structure of human rtf1 plus3 domain in complex with spt5 ctr phosphopeptide 2.42Å AUTH A.D.WIER,M.K.MAYEKAR,A.HEROUX,K.M.ARNDT,A.P.VANDEMARKTITL STRUCTURAL BASIS FOR SPT5-MEDIATED RECRUITMENT OF THE PAF1TITL 2 COMPLEX TO CHROMATIN.REF PROC.NATL.ACAD.SCI.USA V. 110 17290 2013REFN ISSN 0027-8424PMID 24101474DOI 10.1073/PNAS.1314754110 Variant Set Distributions Mapped Variants
General Structure Information 2eko KAT5 solution structure of ruh-073, a pseudo chromo domain from human cdna -1.0Å AUTH A.Z.M.RUHUL MOMEN,H.HIROTA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF RUH-073, A PSEUDO CHROMOTITL 2 DOMAIN FROM HUMAN CDNAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1imj ABHD14B crystal structure of the human ccg1/tafii250-interacting factor b (cib) 2.2Å AUTH B.PADMANABHAN,T.KUZUHARA,N.ADACHI,M.HORIKOSHITITL THE CRYSTAL STRUCTURE OFTITL 2 CCG1/TAF(II)250-INTERACTING FACTOR B (CIB)REF J.BIOL.CHEM. V. 279 9615 2004REFN ISSN 0021-9258PMID 14672934DOI 10.1074/JBC.M312165200 Variant Set Distributions Mapped Variants
General Structure Information 2l51 S100A16 solution structure of calcium bound s100a16 -1.0Å AUTH E.BABINI,I.BERTINI,V.BORSI,V.CALDERONE,X.HU,C.LUCHINAT,AUTH 2 G.PARIGITITL STRUCTURAL CHARACTERIZATION OF HUMAN S100A16, A LOW-AFFINITYTITL 2 CALCIUM BINDER.REF J.BIOL.INORG.CHEM. V. 16 243 2011REFN ISSN 0949-8257PMID 21046186DOI 10.1007/S00775-010-0721-3 Variant Set Distributions Mapped Variants
General Structure Information 3zyg NTNG2 netring2 lam and egf1 domains 2.2Å AUTH E.SEIRADAKE,C.H.COLES,P.V.PERESTENKO,K.HARLOS,AUTH 2 R.A.J.MCILHINNEY,A.R.ARICESCU,E.Y.JONESTITL STRUCTURAL BASIS FOR CELL SURFACE PATTERNINGTITL 2 THROUGH NETRING-NGL INTERACTIONS.REF EMBO J. V. 30 4479 2011REFN ISSN 0261-4189PMID 21946559DOI 10.1038/EMBOJ.2011.346 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3f7g BIRC7 structure of the bir domain from ml-iap bound to a peptidomimetic 2.3Å AUTH F.COHEN,B.ALICKE,L.O.ELLIOTT,J.A.FLYGARE,T.GONCHAROV,AUTH 2 S.F.KETELTAS,M.C.FRANKLIN,S.FRANKOVITZ,J.P.STEPHAN,V.TSUI,AUTH 3 D.VUCIC,H.WONG,W.J.FAIRBROTHERTITL ORALLY BIOAVAILABLE ANTAGONISTS OF INHIBITOR OF APOPTOSISTITL 2 PROTEINS BASED ON AN AZABICYCLOOCTANE SCAFFOLDREF J.MED.CHEM. V. 52 1723 2009REFN ISSN 0022-2623PMID 19228017DOI 10.1021/JM801450C Variant Set Distributions Mapped Variants
General Structure Information 2ymb MITD1 structures of mitd1 3.4Å AUTH M.A.HADDERS,M.AGROMAYOR,T.OBITA,O.PERISIC,A.CABALLE,M.KLOC,AUTH 2 M.H.LAMERS,R.L.WILLIAMS,J.MARTIN-SERRANOTITL ESCRT-III BINDING PROTEIN MITD1 IS INVOLVED IN CYTOKINESISTITL 2 AND HAS AN UNANTICIPATED PLD FOLD THAT BINDS MEMBRANES.REF PROC.NATL.ACAD.SCI.USA V. 109 17424 2012REFN ISSN 0027-8424PMID 23045692DOI 10.1073/PNAS.1206839109 Variant Set Distributions Mapped Variants
General Structure Information 2qq5 DHRS1 crystal structure of human sdr family member 1 1.8Å AUTH E.S.PILKA,V.HOZJAN,E.UGOCHUKWU,F.VON DELFT,M.SUNDSTROM,AUTH 2 C.H.ARROWSMITH,J.WEIGELT,A.EDWARDS,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN SDR FAMILY MEMBER 1.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1siq GCDH the crystal structure and mechanism of human glutaryl-coa dehydrogenase 2.1Å AUTH Z.FU,M.WANG,R.PASCHKE,K.S.RAO,F.E.FRERMAN,J.J.KIMTITL CRYSTAL STRUCTURES OF HUMAN GLUTARYL-COA DEHYDROGENASE WITHTITL 2 AND WITHOUT AN ALTERNATE SUBSTRATE: STRUCTURAL BASES OFTITL 3 DEHYDROGENATION AND DECARBOXYLATION REACTIONSREF BIOCHEMISTRY V. 43 9674 2004REFN ISSN 0006-2960PMID 15274622DOI 10.1021/BI049290C Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 4lij FUBP1 crystal structure of a far upstream element (fuse) binding protein 1 (fubp1) from homo sapiens at 1.95 a resolution 1.8Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 2 PARTNERSHIP FOR T-CELL BIOLOGYTITL CRYSTAL STRUCTURE OF A FAR UPSTREAM ELEMENT (FUSE) BINDINGTITL 2 PROTEIN 1 (FUBP1) FROM HOMO SAPIENS AT 1.95 […]