Assessment of Structural Intolerance and Durability
General Structure Information 4nsq KAT2B crystal structure of pcaf 2.31Å AUTH S.SHI,J.LIN,Y.CAI,J.YU,H.HONG,K.JI,J.S.DOWNEY,X.LU,R.CHEN,AUTH 2 J.HAN,A.HANTITL DIMERIC STRUCTURE OF P300/CBP ASSOCIATED FACTOR.REF BMC STRUCT.BIOL. V. 14 2 2014REFN ESSN 1472-6807PMID 24423233DOI 10.1186/1472-6807-14-2 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2eaq LMO7 crystal structure of pdz domain of kiaa0858 (lim), ms0793 from homo sapiens 1.46Å AUTH Y.XIE,S.KISHISHITA,K.MURAYAMA,C.TAKEMOTO,M.SHIROZU,AUTH 2 S.YOKOYAMATITL CRYSTAL STRUCTURE OF PDZ DOMAIN OF KIAA0858 (LIM),TITL 2 MS0793 FROM HOMO SAPIENSREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2a7l UBE2W structure of the human hypothetical ubiquitin-conjugating enzyme, loc55284 1.82Å AUTH Y.SHENG,J.H.HONG,R.DOHERTY,T.SRIKUMAR,J.SHLOUSH,AUTH 2 G.V.AVVAKUMOV,J.R.WALKER,S.XUE,D.NECULAI,J.W.WAN,S.K.KIM,AUTH 3 C.H.ARROWSMITH,B.RAUGHT,S.DHE-PAGANONTITL A HUMAN UBIQUITIN CONJUGATING ENZYME (E2)-HECT E3 LIGASETITL 2 STRUCTURE-FUNCTION SCREEN.REF MOL CELL PROTEOMICS V. 11 329 2012REFNPMID 22496338DOI 10.1074/MCP.O111.013706 Variant Set Distributions Mapped Variants
General Structure Information 4hc4 PRMT6 human hmt1 hnrnp methyltransferase-like protein 6 (s. cerevisiae) 1.97Å AUTH H.ZENG,A.DONG,H.HE,M.EL BAKKOURI,C.BOUNTRA,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,H.WUTITL THE CRYSTAL STRUCTURE OF HUMAN HMT1 HNRNPTITL 2 METHYLTRANSFERASE-LIKE PROTEIN 6 IN COMPLEX WITH SAHREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2a5j RAB2B crystal structure of human rab2b 1.5Å AUTH J.WANG,A.DONG,Y.SHEN,C.H.ARROWSMITH,A.M.EDWARDS,AUTH 2 M.SUNDSTROM,A.BOCHKAREV,H.W.PARKTITL CRYSTAL STRUCTURE OF HUMAN RAB2BREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2yus SMARCC1 solution structure of the sant domain of human swi/snf- related matrix-associated actin-dependent regulator of chromatin subfamily c member 1 -1.0Å AUTH N.TOCHIO,S.KOSHIBA,K.SATIO,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SANT DOMAIN OF HUMANTITL 2 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENTTITL 3 REGULATOR OF CHROMATIN SUBFAMILY C MEMBER 1REF TO BE PUBLISHEDREFN Variant Set Distributions […]
General Structure Information 1z4r KAT2A human gcn5 acetyltransferase 1.74Å AUTH A.SCHUETZ,G.BERNSTEIN,A.DONG,T.ANTOSHENKO,H.WU,AUTH 2 P.LOPPNAU,A.BOCHKAREV,A.N.PLOTNIKOVTITL CRYSTAL STRUCTURE OF A BINARY COMPLEX BETWEENTITL 2 HUMAN GCN5 HISTONE ACETYLTRANSFERASE DOMAIN ANDTITL 3 ACETYL COENZYME AREF PROTEINS V. 68 403 2007REFN ISSN 0887-3585PMID 17410582DOI 10.1002/PROT.21407 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1x5h NEO1 the solution structure of the third fibronectin type iii domain of human neogenin -1.0Å AUTH N.TOCHIO,A.SASAGAWA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL THE SOLUTION STRUCTURE OF THE THIRD FIBRONECTINTITL 2 TYPE III DOMAIN OF HUMAN NEOGENINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wxp THOC1 solution structure of the death domain of nuclear matrix protein p84 -1.0Å AUTH T.N.NIRAULA,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE DEATH DOMAIN OF NUCLEARTITL 2 MATRIX PROTEIN P84REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2o2o SH3KBP1 solution structure of domain b from human cin85 protein -1.0Å AUTH A.ABABOU,M.PFUHL,I.DIKIC,J.E.LADBURYTITL INVESTIGATION OF DOMAIN B FROM HUMAN CIN85TITL 2 PROTEIN: STRUCTURE, DYNAMICS AND PROLINE-RICHTITL 3 MOTIF BINDINGREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants