General Structure Information
| PDB ID | 4hc4 |
| HGNC Gene Label(s) | PRMT6 |
| Structure Name | human hmt1 hnrnp methyltransferase-like protein 6 (s. cerevisiae) |
| Resolution | 1.97Å |
| Reference | AUTH H.ZENG,A.DONG,H.HE,M.EL BAKKOURI,C.BOUNTRA,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,H.WUTITL THE CRYSTAL STRUCTURE OF HUMAN HMT1 HNRNPTITL 2 METHYLTRANSFERASE-LIKE PROTEIN 6 IN COMPLEX WITH SAHREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 326 |
| Number Of SNVs | 90 |
| Number Of Permutations | 51680 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.031 |
| p-value | 0.005 |
COSMIC
| Number Of Residues | 326 |
| Number Of SNVs | 4 |
| Number Of Permutations | 237 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.167 |
| p-value | 0.084 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 90 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.156 |
| p-value | 0.065 |