Assessment of Structural Intolerance and Durability
General Structure Information 2i3y GPX5 crystal structure of human glutathione peroxidase 5 2.0Å AUTH K.L.KAVANAGH,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN GLUTATHIONE PEROXIDASE 5REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2wo3 EFNA2 crystal structure of the epha4-ephrina2 complex 2.35Å AUTH T.A.BOWDEN,A.R.ARICESCU,J.E.NETTLESHIP,C.SIEBOLD,AUTH 2 N.RAHMAN-HUQ,R.J.OWENS,D.I.STUART,E.Y.JONESTITL STRUCTURAL PLASTICITY OF EPH-RECEPTOR A4 FACILITATESTITL 2 CROSS-CLASS EPHRIN SIGNALLINGREF STRUCTURE V. 17 1386 2009REFN ISSN 0969-2126PMID 19836338DOI 10.1016/J.STR.2009.07.018 Variant Set Distributions Mapped Variants
General Structure Information 1wry SH3BGRL solution structure of the sh3 domain-binding glutamic acid- rich-like protein -1.0Å AUTH K.INOUE,K.MIYAMOTO,T.NAGASHIMA,F.HAYASHI,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SH3 DOMAIN-BINDINGTITL 2 GLUTAMIC ACID-RICH-LIKE PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3pu8 PHF2 phf2 jumonji-nog-fe(ii) complex 1.94Å AUTH J.R.HORTON,A.K.UPADHYAY,H.HASHIMOTO,X.ZHANG,X.CHENGTITL STRUCTURAL BASIS FOR HUMAN PHF2 JUMONJI DOMAIN INTERACTIONTITL 2 WITH METAL IONS.REF J.MOL.BIOL. V. 406 1 2011REFN ISSN 0022-2836PMID 21167174DOI 10.1016/J.JMB.2010.12.013 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2q53 GGCT ensemble refinement of the crystal structure of uncharacterized protein loc79017 from homo sapiens 2.01Å AUTH E.BAE,C.A.BINGMAN,D.J.ACETI,G.N.PHILLIPS JR.TITL CRYSTAL STRUCTURE OF HOMO SAPIENS PROTEIN LOC79017.REF PROTEINS V. 70 588 2008REFN ISSN 0887-3585PMID 17932939DOI 10.1002/PROT.21719 Variant Set Distributions Mapped Variants
General Structure Information 3mdi NUDT21 crystal structure of the 25kda subunit of human cleavage factor im in complex with rna uguaaa 2.07Å AUTH Q.YANG,G.M.GILMARTIN,S.DOUBLIETITL STRUCTURAL BASIS OF UGUA RECOGNITION BY THE NUDIX PROTEINTITL 2 CFI(M)25 AND IMPLICATIONS FOR A REGULATORY ROLE IN MRNA 3TITL 3 PROCESSING.REF PROC.NATL.ACAD.SCI.USA V. 107 10062 2010REFN ISSN 0027-8424PMID 20479262DOI 10.1073/PNAS.1000848107 […]
General Structure Information 1e4u CNOT4 n-terminal ring finger domain of human not-4 -1.0Å AUTH H.HANZAWA,M.J.DE RUWE,T.K.ALBERT,P.C.VAN DER VLIET,AUTH 2 H.T.TIMMERS,R.BOELENSTITL THE STRUCTURE OF THE C4C4 RING FINGER OF HUMANTITL 2 NOT4 REVEALS FEATURES DISTINCT FROM THOSE OF C3HC4TITL 3 RING FINGERSREF J.BIOL.CHEM. V. 276 10185 2001REFN ISSN 0021-9258PMID 11087754DOI 10.1074/JBC.M009298200 Variant Set Distributions Mapped Variants
General Structure Information 2j60 FCN3 h-ficolin complexed to d-fucose 1.8Å AUTH V.GARLATTI,N.BELLOY,L.MARTIN,M.LACROIX,AUTH 2 M.MATSUSHITA,Y.ENDO,T.FUJITA,J.C.FONTECILLA-CAMPS,AUTH 3 G.J.ARLAUD,N.M.THIELENS,C.GABORIAUDTITL STRUCTURAL INSIGHTS INTO THE INNATE IMMUNETITL 2 RECOGNITION SPECIFICITIES OF L- AND H-FICOLINS.REF EMBO J. V. 26 623 2007REFN ISSN 0261-4189PMID 17215869DOI 10.1038/SJ.EMBOJ.7601500 Variant Set Distributions Mapped Variants
General Structure Information 3eg9 SEC24D crystal structure of the mammalian copii-coat protein sec23/24 bound to the transport signal sequence of membrin 3.0Å AUTH J.D.MANCIAS,J.GOLDBERGTITL STRUCTURAL BASIS OF CARGO MEMBRANE PROTEIN DISCRIMINATION BYTITL 2 THE HUMAN COPII COAT MACHINERY.REF EMBO J. V. 27 2918 2008REFN ISSN 0261-4189PMID 18843296DOI 10.1038/EMBOJ.2008.208 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 2ch9 CST7 crystal structure of dimeric human cystatin f 2.1Å AUTH A.W.SCHUTTELKOPF,G.HAMILTON,C.WATTS,D.M.F.VAN AALTENTITL STRUCTURAL BASIS OF REDUCTION-DEPENDENT ACTIVATION OF HUMANTITL 2 CYSTATIN F.REF J.BIOL.CHEM. V. 281 16570 2006REFN ISSN 0021-9258PMID 16601115DOI 10.1074/JBC.M601033200 Variant Set Distributions Mapped Variants