General Structure Information
| PDB ID | 3pu8 |
| HGNC Gene Label(s) | PHF2 |
| Structure Name | phf2 jumonji-nog-fe(ii) complex |
| Resolution | 1.94Å |
| Reference | AUTH J.R.HORTON,A.K.UPADHYAY,H.HASHIMOTO,X.ZHANG,X.CHENGTITL STRUCTURAL BASIS FOR HUMAN PHF2 JUMONJI DOMAIN INTERACTIONTITL 2 WITH METAL IONS.REF J.MOL.BIOL. V. 406 1 2011REFN ISSN 0022-2836PMID 21167174DOI 10.1016/J.JMB.2010.12.013 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 365 |
| Number Of SNVs | 53 |
| Number Of Permutations | 9985 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.288 |
| p-value | 0.094 |
COSMIC
| Number Of Residues | 365 |
| Number Of SNVs | 7 |
| Number Of Permutations | 1920 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.048 |
| p-value | 0.354 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 53 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 30.0 |
| K Statistic | 0.222 |
| p-value | 0.627 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
