Assessment of Structural Intolerance and Durability
General Structure Information 2miu FHL2 structure of fhl2 lim adaptor and its interaction with ski -1.0Å AUTH Y.YANG,Y.SUN,E.E.MEDRANO,X.TIAN,M.A.WEISSTITL STRUCTURE OF FHL2 LIM ADAPTOR AND ITS INTERACTION WITH SKIREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4a63 TP53BP2 crystal structure of the p73-aspp2 complex at 2.6a resolution 2.27Å AUTH P.CANNING,F.VON DELFT,A.N.BULLOCKTITL STRUCTURAL BASIS FOR ASPP2 RECOGNITION BY THE TUMORTITL 2 SUPPRESSOR P73.REF J.MOL.BIOL. V. 423 515 2012REFN ISSN 0022-2836PMID 22917970DOI 10.1016/J.JMB.2012.08.005 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 4cgy TOP3A crystal structure of the human topoisomerase iii alpha-rmi1 complex 2.85Å AUTH N.BOCQUET,A.H.BIZARD,W.ABDULRAHMAN,N.B.LARSEN,M.FATY,AUTH 2 S.CAVADINI,R.D.BUNKER,S.C.KOWALCZYKOWSKI,P.CEJKA,AUTH 3 I.D.HICKSON,N.H.THOMATITL STRUCTURAL AND MECHANISTIC INSIGHT INTO HOLLIDAY-JUNCTIONTITL 2 DISSOLUTION BY TOPOISOMERASE IIIALPHA AND RMI1REF NAT.STRUCT.MOL.BIOL. V. 21 261 2014REFN ISSN 1545-9993PMID 24509834DOI 10.1038/NSMB.2775 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 3ecs EIF2B1 crystal structure of human eif2b alpha 2.65Å AUTH T.B.HIYAMA,T.ITO,H.IMATAKA,S.YOKOYAMATITL CRYSTAL STRUCTURE OF THE ALPHA SUBUNIT OF HUMAN TRANSLATIONTITL 2 INITIATION FACTOR 2BREF J.MOL.BIOL. V. 392 937 2009REFN ISSN 0022-2836PMID 19631657DOI 10.1016/J.JMB.2009.07.054 Variant Set Distributions Mapped Variants
General Structure Information 1y7x MVP solution structure of a two-repeat fragment of major vault protein -1.0Å AUTH G.KOZLOV,O.VAVELYUK,O.MINAILIUC,D.BANVILLE,AUTH 2 K.GEHRING,I.EKIELTITL SOLUTION STRUCTURE OF A TWO-REPEAT FRAGMENT OFTITL 2 MAJOR VAULT PROTEIN.REF J.MOL.BIOL. V. 356 444 2006REFN ISSN 0022-2836PMID 16373071DOI 10.1016/J.JMB.2005.11.064 Variant Set Distributions Mapped Variants
General Structure Information 4bkn DPYSL3 human dihydropyrimidinase-related protein 3 (dpysl3) 2.1Å AUTH S.MATHEATITL STRUCTURE OF DPYSL3REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2k9u FLNC solution nmr structure of the filamin-migfilin complex -1.0Å AUTH S.S.ITHYCHANDA,M.DAS,Y.Q.MA,K.DING,X.WANG,S.GUPTA,C.WU,AUTH 2 E.F.PLOW,J.QINTITL MIGFILIN, A MOLECULAR SWITCH IN REGULATION OF INTEGRINTITL 2 ACTIVATION.REF J.BIOL.CHEM. V. 284 4713 2009REFN ISSN 0021-9258PMID 19074766DOI 10.1074/JBC.M807719200 Variant Set Distributions Mapped Variants
General Structure Information 3f31 SPTAN1 crystal structure of the n-terminal region of alphaii-spectrin tetramerization domain 2.3Å AUTH S.MEHBOOB,Y.SONG,M.WITEK,F.LONG,B.D.SANTARSIERO,AUTH 2 M.E.JOHNSON,L.W.FUNGTITL CRYSTAL STRUCTURE OF THE NONERYTHROID ALPHA-SPECTRINTITL 2 TETRAMERIZATION SITE REVEALS DIFFERENCES BETWEEN ERYTHROIDTITL 3 AND NONERYTHROID SPECTRIN TETRAMER FORMATION.REF J.BIOL.CHEM. V. 285 14572 2010REFN ISSN 0021-9258PMID 20228407DOI 10.1074/JBC.M109.080028 Variant Set Distributions Mapped Variants
General Structure Information 1a02 NFATC2 structure of the dna binding domains of nfat, fos and jun bound to dna 2.7Å AUTH L.CHEN,J.N.GLOVER,P.G.HOGAN,A.RAO,S.C.HARRISONTITL STRUCTURE OF THE DNA-BINDING DOMAINS FROM NFAT,TITL 2 FOS AND JUN BOUND SPECIFICALLY TO DNA.REF NATURE V. 392 42 1998REFN ISSN 0028-0836PMID 9510247DOI 10.1038/32100 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 2k60 STIM1 nmr structure of calcium-loaded stim1 ef-sam -1.0Å AUTH P.B.STATHOPULOS,L.ZHENG,G.Y.LI,M.J.PLEVIN,M.IKURATITL STRUCTURAL AND MECHANISTIC INSIGHTS INTO STIM1-MEDIATEDTITL 2 INITIATION OF STORE-OPERATED CALCIUM ENTRY.REF CELL(CAMBRIDGE,MASS.) V. 135 110 2008REFN ISSN 0092-8674PMID 18854159DOI 10.1016/J.CELL.2008.08.006 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants