Assessment of Structural Intolerance and Durability
General Structure Information 2c52 NCOA1 structural diversity in cbp p160 complexes -1.0Å AUTH L.C.WATERS,B.YUE,V.VEVERKA,P.S.RENSHAW,J.BRAMHAM,AUTH 2 S.MATSUDA,T.FRENKIEL,G.KELLY,F.W.MUSKETT,M.D.CARR,AUTH 3 D.M.HEERYTITL STRUCTURAL DIVERSITY IN P160/CREB-BINDING PROTEINTITL 2 COACTIVATOR COMPLEXES.REF J.BIOL.CHEM. V. 281 14787 2006REFN ISSN 0021-9258PMID 16540468DOI 10.1074/JBC.M600237200 Variant Set Distributions Mapped Variants
General Structure Information 2kz5 NFE2 solution nmr structure of transcription factor nf-e2 subunits dna binding domain from homo sapiens, northeast structural genomics consortium target hr4653b -1.0Å AUTH G.LIU,H.JANJUA,R.XIAO,C.CICCOSANTI,R.SHASTRY,T.B.ACTON,AUTH 2 S.TONG,J.K.EVERETT,G.T.MONTELIONETITL NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HR4653BREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wlz EFCAB6 crystal structure of djbp fragment which was obtained by limited proteolysis 1.6Å AUTH K.HONBOU,N.SUZUKI,M.HORIUCHI,T.TAIRA,T.NIKI,AUTH 2 H.ARIGA,F.INAGAKITITL CRYSTAL STRUCTURE OF DJBP FRAGMENT WHICH WASTITL 2 OBTAINED BY LIMITED PROTEOLYSISREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2l3l TBCC the solution structure of the n-terminal domain of human tubulin binding cofactor c reveals a platform for the interaction with ab- tubulin -1.0Å AUTH M.F.GARCIA-MAYORAL,R.CASTANO,M.L.LOPEZ-FANARRAGA,J.C.ZABALA,AUTH 2 M.RICO,M.BRUIXTITL THE SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMANTITL 2 TUBULIN BINDING COFACTOR C REVEALS A PLATFORM FOR TUBULINTITL 3 INTERACTIONREF TO BE […]
General Structure Information 4iy3 CNNM4 structural and ligand binding properties of the bateman domain of human magnesium transporters cnnm2 and cnnm4 3.6Å AUTH M.A.CORRAL-RODRIGUEZ,M.STUIVER,J.A.ENCINAR,V.SPIWOK,AUTH 2 I.GOMEZ-GARCIA,I.OYENARTE,J.ERENO-ORBEA,H.TERASHIMA,AUTH 3 A.ACCARDI,T.DIERCKS,D.MULLER,L.A.MARTINEZ-CRUZTITL STRUCTURAL AND LIGAND BINDING PROPERTIES OF THE BATEMANTITL 2 DOMAIN OF HUMAN MAGNESIUM TRANSPORTERS CNNM2 AND CNNM4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3qxl RALGPS1 crystal structure of the cdc25 domain from ral-specific guanine- nucleotide exchange factor ralgps1a 2.24Å AUTH W.PENG,J.XU,X.GUAN,Y.SUN,X.C.ZHANG,X.LI,Z.RAOTITL STRUCTURAL STUDY OF THE CDC25 DOMAIN FROM RAL-SPECIFICTITL 2 GUANINE-NUCLEOTIDE EXCHANGE FACTOR RALGPS1A.REF PROTEIN CELL V. 2 308 2011REFN ISSN 1674-800XPMID 21494904DOI 10.1007/S13238-011-1036-Z Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 2eo1 OBSCN solution structure of the ig domain of human obscn protein -1.0Å AUTH K.NAGASHIMA,T.NAGASHIMA,M.YOSHIDA,F.HAYASHI,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE IG DOMAIN OF HUMAN OBSCNTITL 2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3se2 PARP14 human poly(adp-ribose) polymerase 14 (parp14/artd8) – catalytic domain in complex with 6(5h)-phenanthridinone 2.3Å AUTH E.WAHLBERG,T.KARLBERG,E.KOUZNETSOVA,N.MARKOVA,A.MACCHIARULO,AUTH 2 A.G.THORSELL,E.POL,A.FROSTELL,T.EKBLAD,D.ONCU,B.KULL,AUTH 3 G.M.ROBERTSON,R.PELLICCIARI,H.SCHULER,J.WEIGELTTITL FAMILY-WIDE CHEMICAL PROFILING AND STRUCTURAL ANALYSIS OFTITL 2 PARP AND TANKYRASE INHIBITORS.REF NAT.BIOTECHNOL. V. 30 283 2012REFN ISSN 1087-0156PMID 22343925DOI 10.1038/NBT.2121 Variant Set Distributions Mapped Variants
General Structure Information 1wfo SDK2 the eighth fn3 domain of human sidekick-2 -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL THE EIGHTH FN3 DOMAIN OF HUMAN SIDEKICK-2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4bou OTUD3 structure of otud3 otu domain 1.55Å AUTH T.E.T.MEVISSEN,M.K.HOSPENTHAL,P.P.GEURINK,P.R.ELLIOTT,AUTH 2 M.AKUTSU,N.ARNAUDO,R.EKKEBUS,Y.KULATHU,T.WAUER,F.EL OUALID,AUTH 3 S.M.V.FREUND,H.OVAA,D.KOMANDERTITL OTU DEUBIQUITINASES REVEAL MECHANISMS OF LINKAGETITL 2 SPECIFICITY AND ENABLE UBIQUITIN CHAIN RESTRICTIONTITL 3 ANALYSIS.REF CELL(CAMBRIDGE,MASS.) V. 154 169 2013REFN ISSN 0092-8674PMID 23827681DOI 10.1016/J.CELL.2013.05.046 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]