Assessment of Structural Intolerance and Durability
General Structure Information 3pd7 TOPBP1 crystal structure of the sixth brct domain of human topbp1 1.26Å AUTH J.LEE,C.XU,G.CUI,J.R.THOMPSON,G.MERTITL CRYSTAL STRUCTURE OF THE SIXTH BRCT DOMAIN OF HUMAN TOPBP1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3mb3 PHIP crystal structure of the second bromodomain of pleckstrin homology domain interacting protein (phip) 2.25Å AUTH P.FILIPPAKOPOULOS,S.PICAUD,M.MANGOS,T.KEATES,J.P.LAMBERT,AUTH 2 D.BARSYTE-LOVEJOY,I.FELLETAR,R.VOLKMER,S.MULLER,T.PAWSON,AUTH 3 A.C.GINGRAS,C.H.ARROWSMITH,S.KNAPPTITL HISTONE RECOGNITION AND LARGE-SCALE STRUCTURAL ANALYSIS OFTITL 2 THE HUMAN BROMODOMAIN FAMILY.REF CELL(CAMBRIDGE,MASS.) V. 149 214 2012REFN ISSN 0092-8674PMID 22464331DOI 10.1016/J.CELL.2012.02.013 Variant Set Distributions Mapped Variants
General Structure Information 2huz GNPNAT1 crystal structure of gnpnat1 2.67Å AUTH H.WU,J.MIN,H.ZENG,P.LOPPNAU,J.WEIGELT,M.SUNDSTROM,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,A.N.PLOTNIKOVTITL CRYSTAL STRUCTURE OF GLUCOSAMINE-PHOSPHATETITL 2 N-ACETYLTRANSFERASE 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1uey NRCAM solution structure of the first fibronectin type iii domain of human kiaa0343 protein -1.0Å AUTH C.ZHAO,T.KIGAWA,Y.MUTO,S.KOSHIBA,N.TOCHIO,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST FIBRONECTIN TYPETITL 2 III DOMAIN OF HUMAN KIAA0343 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2if7 SLAMF6 crystal structure of ntb-a 3.0Å AUTH E.CAO,U.A.RAMAGOPAL,A.FEDOROV,E.FEDOROV,Q.YAN,J.W.LARY,AUTH 2 J.L.COLE,S.G.NATHENSON,S.C.ALMOTITL NTB-A RECEPTOR CRYSTAL STRUCTURE: INSIGHTS INTO HOMOPHILICTITL 2 INTERACTIONS IN THE SIGNALING LYMPHOCYTIC ACTIVATIONTITL 3 MOLECULE RECEPTOR FAMILY.REF IMMUNITY V. 25 559 2006REFN ISSN 1074-7613PMID 17045824DOI 10.1016/J.IMMUNI.2006.06.020 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]
General Structure Information 1um7 DLG3 solution structure of the third pdz domain of synapse- associated protein 102 -1.0Å AUTH X.-R.QIN,T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE THIRD PDZ DOMAIN OFTITL 2 SYNAPSE-ASSOCIATED PROTEIN 102REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2yt4 DGCR8 crystal structure of human dgcr8 core 2.6Å AUTH S.Y.SOHN,W.J.BAE,J.J.KIM,K.H.YEOM,V.N.KIM,Y.CHOTITL CRYSTAL STRUCTURE OF HUMAN DGCR8 COREREF NAT.STRUCT.MOL.BIOL. V. 14 847 2007REFN ISSN 1545-9993PMID 17704815DOI 10.1038/NSMB1294 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2hh2 KHSRP solution structure of the fourth kh domain of ksrp -1.0Å AUTH M.F.GARCIA-MAYORAL,D.HOLLINGWORTH,L.MASINO,AUTH 2 I.DIAZ-MORENO,G.KELLY,R.GHERZI,C.F.CHOU,C.Y.CHEN,AUTH 3 A.RAMOSTITL THE STRUCTURE OF THE C-TERMINAL KH DOMAINS OF KSRPTITL 2 REVEALS A NONCANONICAL MOTIF IMPORTANT FOR MRNATITL 3 DEGRADATION.REF STRUCTURE V. 15 485 2007REFN ISSN 0969-2126PMID 17437720DOI 10.1016/J.STR.2007.03.006 Variant Set Distributions Mapped Variants
General Structure Information 2bkr SENP8 nedd8 nedp1 complex 1.9Å AUTH L.N.SHEN,H.LIU,C.DONG,D.XIRODIMAS,J.H.NAISMITH,R.T.HAYTITL STRUCTURAL BASIS OF NEDD8 UBIQUITIN DISCRIMINATION BY THETITL 2 DENEDDYLATING ENZYME NEDP1REF EMBO J. V. 24 1341 2005REFN ISSN 0261-4189PMID 15775960DOI 10.1038/SJ.EMBOJ.7600628 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1j4w FUBP1 complex of the kh3 and kh4 domains of fbp with a single_stranded 29mer dna oligonucleotide from the fuse element of the c-myc oncogene -1.0Å AUTH D.T.BRADDOCK,J.M.LOUIS,J.L.BABER,D.LEVENS,G.M.CLORETITL STRUCTURE AND DYNAMICS OF KH DOMAINS FROM FBPTITL 2 BOUND TO SINGLE-STRANDED DNA.REF NATURE V. 415 1051 2002REFN ISSN 0028-0836PMID 11875576DOI 10.1038/4151051A Variant Set […]