General Structure Information
| PDB ID | 2bkr |
| HGNC Gene Label(s) | SENP8 |
| Structure Name | nedd8 nedp1 complex |
| Resolution | 1.9Å |
| Reference | AUTH L.N.SHEN,H.LIU,C.DONG,D.XIRODIMAS,J.H.NAISMITH,R.T.HAYTITL STRUCTURAL BASIS OF NEDD8 UBIQUITIN DISCRIMINATION BY THETITL 2 DENEDDYLATING ENZYME NEDP1REF EMBO J. V. 24 1341 2005REFN ISSN 0261-4189PMID 15775960DOI 10.1038/SJ.EMBOJ.7600628 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 212 |
| Number Of SNVs | 39 |
| Number Of Permutations | 17904 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.028 |
| p-value | 0.748 |
COSMIC
| Number Of Residues | 212 |
| Number Of SNVs | 3 |
| Number Of Permutations | 76 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.667 |
| p-value | 0.063 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 39 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.57 |
| p-value | 0.077 |