Assessment of Structural Intolerance and Durability
General Structure Information 1elk TOM1 vhs domain of tom1 protein from h. sapiens 1.5Å AUTH S.MISRA,B.BEACH,J.H.HURLEYTITL STRUCTURE OF THE VHS DOMAIN OF HUMAN TOM1 (TARGETTITL 2 OF MYB 1): INSIGHTS INTO INTERACTIONS WITHTITL 3 PROTEINS AND MEMBRANESREF BIOCHEMISTRY V. 39 11282 2000REFN ISSN 0006-2960PMID 10985773DOI 10.1021/BI0013546 Variant Set Distributions Mapped Variants
General Structure Information 2eed FLNB solution structure of the 24th filamin domain from human filamin-b -1.0Å AUTH T.TOMIZAWA,S.KOSHIBA,S.WATANABE,T.HARADA,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 24TH FILAMIN DOMAIN FROMTITL 2 HUMAN FILAMIN-BREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3lfv PDE5A crystal structure of unliganded pde5a gaf domain 2.8Å AUTH H.WANG,H.ROBINSON,H.KETITL CONFORMATION CHANGES, N-TERMINAL INVOLVEMENT, AND CGMPTITL 2 SIGNAL RELAY IN THE PHOSPHODIESTERASE-5 GAF DOMAIN.REF J.BIOL.CHEM. V. 285 38149 2010REFN ISSN 0021-9258PMID 20861010DOI 10.1074/JBC.M110.141614 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2dic FLNB solution structure of the 12th filamin domain from human filamin-b -1.0Å AUTH T.TOMIZAWA,S.KOSHIBA,S.WATANABE,T.HARADA,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 12TH FILAMIN DOMAIN FROMTITL 2 HUMAN FILAMIN-BREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1nty TRIO crystal structure of the first dh/ph domain of trio to 1.7 a 1.7Å AUTH K.R.SKOWRONEK,F.GUO,Y.ZHENG,N.NASSARTITL THE C-TERMINAL BASIC TAIL OF RHOG ASSISTS THE GUANINETITL 2 NUCLEOTIDE EXCHANGE FACTOR TRIO IN BINDING TO PHOSPHOLIPIDS.REF J.BIOL.CHEM. V. 279 37895 2004REFN ISSN 0021-9258PMID 15199069DOI 10.1074/JBC.M312677200 Variant Set Distributions Mapped Variants
General Structure Information 3hu6 SPOP structures of spop-substrate complexes: insights into molecular architectures of btb-cul3 ubiquitin ligases: spopmathx/btb/3-box-pucsbc1 2.7Å AUTH M.ZHUANG,M.F.CALABRESE,J.LIU,M.B.WADDELL,A.NOURSE,AUTH 2 M.HAMMEL,D.J.MILLER,H.WALDEN,D.M.DUDA,S.N.SEYEDIN,AUTH 3 T.HOGGARD,J.W.HARPER,K.P.WHITE,B.A.SCHULMANTITL STRUCTURES OF SPOP-SUBSTRATE COMPLEXES: INSIGHTSTITL 2 INTO MOLECULAR ARCHITECTURES OF BTB-CUL3 UBIQUITINTITL 3 LIGASES.REF MOL.CELL V. 36 39 2009REFN ISSN 1097-2765PMID 19818708DOI 10.1016/J.MOLCEL.2009.09.022 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 2pxx ECE2 human putative methyltransferase mgc2408 1.3Å AUTH W.TEMPEL,H.WU,L.DOMBROVSKY,H.ZENG,P.LOPPNAU,H.ZHU,AUTH 2 A.N.PLOTNIKOV,A.BOCHKAREVTITL AN INTACT SAM-DEPENDENT METHYLTRANSFERASE FOLD ISTITL 2 ENCODED BY THE HUMAN ENDOTHELIN-CONVERTING ENZYME-2TITL 3 GENE.REF PROTEINS V. 74 789 2009REFN ISSN 0887-3585PMID 19089949DOI 10.1002/PROT.22299 Variant Set Distributions Mapped Variants
General Structure Information 2yan GLRX3 crystal structure of the second glutaredoxin domain of human txnl2 1.9Å AUTH M.VOLLMAR,C.JOHANSSON,R.COCKING,J.R.C.MUNIZ,T.KROJER,AUTH 2 C.ALLERSTON,F.VON DELFT,C.BOUNTRA,C.H.ARROWSMITH,J.WEIGELT,AUTH 3 A.EDWARDS,U.OPPERMANNTITL CRYSTAL STRUCTURE OF THE SECOND GLUTAREDOXIN DOMAIN OFTITL 2 HUMAN TXNL2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3i2v MOCS3 crystal structure of human mocs3 rhodanese-like domain 1.25Å AUTH J.P.BACIK,J.R.WALKER,L.LOPEZ,Y.LI,J.WEIGELT,AUTH 2 C.BOUNTRA,C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,AUTH 3 S.DHE-PAGANONTITL CRYSTAL STRUCTURE OF THE HUMAN MOCS3 RHODANESE-LIKETITL 2 DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3e6u LANCL1 crystal structure of human lancl1 2.6Å AUTH W.ZHANG,L.WANG,Y.LIU,J.XU,G.ZHU,H.CANG,X.LI,AUTH 2 M.BARTLAM,K.HENSLEY,G.LI,Z.RAO,X.C.ZHANGTITL STRUCTURE OF HUMAN LANTHIONINE SYNTHETASE C-LIKETITL 2 PROTEIN 1 AND ITS INTERACTION WITH EPS8 ANDTITL 3 GLUTATHIONEREF GENES DEV. V. 23 1387 2009REFN ISSN 0890-9369PMID 19528316DOI 10.1101/GAD.1789209 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]