Assessment of Structural Intolerance and Durability
General Structure Information 3kzd TIAM1 crystal structure of free t-cell lymphoma invasion and metastasis-1 pdz domain 1.3Å AUTH T.R.SHEPHERD,S.M.KLAUS,X.LIU,S.RAMASWAMY,K.A.DEMALI,AUTH 2 E.J.FUENTESTITL THE TIAM1 PDZ DOMAIN COUPLES TO SYNDECAN1 AND PROMOTESTITL 2 CELL-MATRIX ADHESION.REF J.MOL.BIOL. V. 398 730 2010REFN ISSN 0022-2836PMID 20361982DOI 10.1016/J.JMB.2010.03.047 Variant Set Distributions Mapped Variants
General Structure Information 2md7 SP140 nmr structure of human sp140 phd finger trans conformer -1.0Å AUTH C.ZUCCHELLI,S.TAMBURRI,G.QUILICI,E.PALAGANO,A.BERARDI,AUTH 2 M.SAARE,P.PETERSON,A.BACHI,G.MUSCOTITL STRUCTURE OF HUMAN SP140 PHD FINGER: AN ATYPICAL FOLDTITL 2 INTERACTING WITH PIN1.REF FEBS J. V. 281 216 2014REFN ISSN 1742-464XPMID 24267382DOI 10.1111/FEBS.12588 Variant Set Distributions Mapped Variants
General Structure Information 3io2 EP300 crystal structure of the taz2 domain of p300 2.5Å AUTH M.MILLER,Z.DAUTER,S.CHERRY,J.E.TROPEA,A.WLODAWERTITL STRUCTURE OF THE TAZ2 DOMAIN OF P300: INSIGHTS INTO LIGANDTITL 2 BINDING.REF ACTA CRYSTALLOGR.,SECT.D V. 65 1301 2009REFN ISSN 0907-4449PMID 19966416DOI 10.1107/S0907444909040153 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4ny0 PTK2 crystal structure of ferm domain of human focal adhesion kinase 2.8Å AUTH K.BRAMI-CHERRIER,N.GERVASI,D.ARSENIEVA,K.WALKIEWICZ,AUTH 2 M.C.BOUTTERIN,A.ORTEGA,P.G.LEONARD,B.SEANTIER,L.GASMI,AUTH 3 T.BOUCEBA,G.KADARE,J.A.GIRAULT,S.T.AROLDTITL FAK DIMERIZATION CONTROLS ITS KINASE-DEPENDENT FUNCTIONS ATTITL 2 FOCAL ADHESIONS.REF EMBO J. V. 33 356 2014REFN ISSN 0261-4189PMID 24480479DOI 10.1002/EMBJ.201386399 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2qv2 OCRL a role of the lowe syndrome protein ocrl in early steps of the endocytic pathway 2.4Å AUTH K.S.ERDMANN,Y.MAO,H.J.MCCREA,R.ZONCU,S.LEE,AUTH 2 S.PARADISE,J.MODREGGER,D.BIEMESDERFER,D.TOOMRE,AUTH 3 P.DE CAMILLITITL A ROLE OF THE LOWE SYNDROME PROTEIN OCRL IN EARLYTITL 2 STEPS OF THE ENDOCYTIC PATHWAYREF DEV.CELL V. 13 377 2007REFN ISSN 1534-5807PMID 17765681DOI 10.1016/J.DEVCEL.2007.08.004 Variant Set […]
General Structure Information 2qv2 OCRL a role of the lowe syndrome protein ocrl in early steps of the endocytic pathway 2.4Å AUTH K.S.ERDMANN,Y.MAO,H.J.MCCREA,R.ZONCU,S.LEE,AUTH 2 S.PARADISE,J.MODREGGER,D.BIEMESDERFER,D.TOOMRE,AUTH 3 P.DE CAMILLITITL A ROLE OF THE LOWE SYNDROME PROTEIN OCRL IN EARLYTITL 2 STEPS OF THE ENDOCYTIC PATHWAYREF DEV.CELL V. 13 377 2007REFN ISSN 1534-5807PMID 17765681DOI 10.1016/J.DEVCEL.2007.08.004 Variant Set […]
General Structure Information 2qv2 OCRL a role of the lowe syndrome protein ocrl in early steps of the endocytic pathway 2.4Å AUTH K.S.ERDMANN,Y.MAO,H.J.MCCREA,R.ZONCU,S.LEE,AUTH 2 S.PARADISE,J.MODREGGER,D.BIEMESDERFER,D.TOOMRE,AUTH 3 P.DE CAMILLITITL A ROLE OF THE LOWE SYNDROME PROTEIN OCRL IN EARLYTITL 2 STEPS OF THE ENDOCYTIC PATHWAYREF DEV.CELL V. 13 377 2007REFN ISSN 1534-5807PMID 17765681DOI 10.1016/J.DEVCEL.2007.08.004 Variant Set […]
General Structure Information 1p5q FKBP4 crystal structure of fkbp52 c-terminal domain 2.8Å AUTH B.WU,P.LI,Y.LIU,Z.LOU,Y.DING,C.SHU,S.YE,M.BARTLAM,B.SHEN,AUTH 2 Z.RAOTITL 3D STRUCTURE OF HUMAN FK506-BINDING PROTEIN 52: IMPLICATIONSTITL 2 FOR THE ASSEMBLY OF THE GLUCOCORTICOIDTITL 3 RECEPTOR/HSP90/IMMUNOPHILIN HETEROCOMPLEXREF PROC.NATL.ACAD.SCI.USA V. 101 8348 2004REFN ISSN 0027-8424PMID 15159550DOI 10.1073/PNAS.0305969101 Variant Set Distributions Mapped Variants
General Structure Information 2lmi GRSF1 nmr structure of the protein bc040485 from homo sapiens -1.0Å AUTH S.K.DUTTA,P.SERRANO,M.GERALT,K.WUTHRICH,AUTH 2 JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 3 PARTNERSHIP FOR T-CELL BIOLOGY (TCELL)TITL NMR STRUCTURE OF THE HUMAN RNA BINDING PROTEIN BC040485REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2lmi GRSF1 nmr structure of the protein bc040485 from homo sapiens -1.0Å AUTH S.K.DUTTA,P.SERRANO,M.GERALT,K.WUTHRICH,AUTH 2 JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 3 PARTNERSHIP FOR T-CELL BIOLOGY (TCELL)TITL NMR STRUCTURE OF THE HUMAN RNA BINDING PROTEIN BC040485REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants