Assessment of Structural Intolerance and Durability
General Structure Information 1x5g NEO1 the solution structure of the second fibronectin type iii domain of human neogenin -1.0Å AUTH N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL THE SOLUTION STRUCTURE OF THE SECOND FIBRONECTINTITL 2 TYPE III DOMAIN OF HUMAN NEOGENINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2lor TMEM141 backbone structure of human membrane protein tmem141 -1.0Å AUTH C.KLAMMT,I.MASLENNIKOV,M.BAYRHUBER,C.EICHMANN,N.VAJPAI,AUTH 2 E.J.CHIU,K.Y.BLAIN,L.ESQUIVIES,J.H.KWON,B.BALANA,U.PIEPER,AUTH 3 A.SALI,P.A.SLESINGER,W.KWIATKOWSKI,R.RIEK,S.CHOETITL FACILE BACKBONE STRUCTURE DETERMINATION OF HUMAN MEMBRANETITL 2 PROTEINS BY NMR SPECTROSCOPY.REF NAT.METHODS V. 9 834 2012REFN ISSN 1548-7091PMID 22609626DOI 10.1038/NMETH.2033 Variant Set Distributions Mapped Variants
General Structure Information 1wlj ISG20 human isg20 1.9Å AUTH T.HORIO,M.MURAI,T.INOUE,T.HAMASAKI,T.TANAKA,T.OHGITITL CRYSTAL STRUCTURE OF HUMAN ISG20, ANTITL 2 INTERFERON-INDUCED ANTIVIRAL RIBONUCLEASEREF FEBS LETT. V. 577 111 2004REFN ISSN 0014-5793PMID 15527770DOI 10.1016/J.FEBSLET.2004.09.074 Variant Set Distributions Mapped Variants
General Structure Information 2fue PMM1 human alpha-phosphomannomutase 1 with d-mannose 1-phosphate and mg2+ cofactor bound 1.75Å AUTH N.R.SILVAGGI,C.ZHANG,Z.LU,J.DAI,D.DUNAWAY-MARIANO,K.N.ALLENTITL THE X-RAY CRYSTAL STRUCTURES OF HUMANTITL 2 ALPHA-PHOSPHOMANNOMUTASE 1 REVEAL THE STRUCTURAL BASIS OFTITL 3 CONGENITAL DISORDER OF GLYCOSYLATION TYPE 1A.REF J.BIOL.CHEM. V. 281 14918 2006REFN ISSN 0021-9258PMID 16540464DOI 10.1074/JBC.M601505200 Variant Set Distributions Mapped Variants
General Structure Information 3p4l NEO1 crystal structure of a hemojuvelin-binding fragment of neogenin 1.8Å AUTH F.YANG,A.P.WEST,P.J.BJORKMANTITL CRYSTAL STRUCTURE OF A HEMOJUVELIN-BINDING FRAGMENT OFTITL 2 NEOGENIN AT 1.8A.REF J.STRUCT.BIOL. V. 174 239 2011REFN ISSN 1047-8477PMID 20971194DOI 10.1016/J.JSB.2010.10.005 Variant Set Distributions Mapped Variants
General Structure Information 4fq3 TNPO1 crystal structure of transportin/fus-nls 3.0Å AUTH W.GONG,C.NIU,M.JIA,F.GAOTITL CRYSTAL STRUCTURE OF TRANSPORTIN/FUS-NLSREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 4has SNX27 crystal structure of px domain of human sorting nexin snx27 1.74Å AUTH D.S.FROESE,T.KROJER,C.STRAIN-DAMERELL,C.ALLERSTON,W.KIYANI,AUTH 2 N.BURGESS-BROWN,F.VON DELFT,C.ARROWSMITH,C.BOUNTRA,AUTH 3 A.EDWARDS,W.W.YUE,STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL CRYSTAL STRUCTURE OF PX DOMAIN OF HUMAN SORTING NEXIN SNX27REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3m66 MTERFD1 crystal structure of human mitochondrial transcription termination factor 3 1.6Å AUTH H.SPAHR,T.SAMUELSSON,B.M.HALLBERG,C.M.GUSTAFSSONTITL STRUCTURE OF MITOCHONDRIAL TRANSCRIPTION TERMINATION FACTORTITL 2 3 REVEALS A NOVEL NUCLEIC ACID-BINDING DOMAIN.REF BIOCHEM.BIOPHYS.RES.COMMUN. V. 397 386 2010REFN ISSN 0006-291XPMID 20430012DOI 10.1016/J.BBRC.2010.04.130 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2yuj UFD1L solution structure of human ubiquitin fusion degradation protein 1 homolog ufd1 -1.0Å AUTH K.SAITO,T.TOMIZAWA,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF HUMAN UBIQUITIN FUSIONTITL 2 DEGRADATION PROTEIN 1 HOMOLOG UFD1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4jhn RPGR the crystal structure of the rpgr rcc1-like domain 1.7Å AUTH D.WATZLICH,I.VETTER,K.GOTTHARDT,M.MIERTZSCHKE,Y.X.CHEN,AUTH 2 A.WITTINGHOFER,S.ISMAILTITL THE INTERPLAY BETWEEN RPGR, PDE-DELTA AND ARL2/3 REGULATETITL 2 THE CILIARY TARGETING OF FARNESYLATED CARGO.REF EMBO REP. V. 14 465 2013REFN ISSN 1469-221XPMID 23559067DOI 10.1038/EMBOR.2013.37 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]