Assessment of Structural Intolerance and Durability
General Structure Information 2zix MUS81 crystal structure of the mus81-eme1 complex 3.5Å AUTH J.H.CHANG,J.J.KIM,J.M.CHOI,J.H.LEE,Y.CHOTITL CRYSTAL STRUCTURE OF THE MUS81-EME1 COMPLEXREF GENES DEV. V. 22 1093 2008REFN ISSN 0890-9369PMID 18413719DOI 10.1101/GAD.1618708 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1kcg ULBP3 nkg2d in complex with ulbp3 2.6Å AUTH S.RADAEV,B.ROSTRO,A.G.BROOKS,M.COLONNA,P.D.SUNTITL CONFORMATIONAL PLASTICITY REVEALED BY THETITL 2 COCRYSTAL STRUCTURE OF NKG2D AND ITS CLASS ITITL 3 MHC-LIKE LIGAND ULBP3.REF IMMUNITY V. 15 1039 2001REFN ISSN 1074-7613PMID 11754823DOI 10.1016/S1074-7613(01)00241-2 Variant Set Distributions Mapped Variants
General Structure Information 2db6 STAC3 solution structure of rsgi ruh-051, a c1 domain of stac3 from human cdna -1.0Å AUTH T.ABE,C.KUROSAKI,M.YOSHIDA,F.HAYASHI,H.HIROTA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-051, A C1 DOMAIN OFTITL 2 STAC3 FROM HUMAN CDNAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3op5 VRK1 human vaccinia-related kinase 1 2.4Å AUTH C.K.ALLERSTON,S.UTTARKAR,P.SAVITSKY,J.M.ELKINS,AUTH 2 P.FILIPPAKOPOULOS,T.KROJER,P.RELLOS,O.FEDOROV,J.ESWARAN,AUTH 3 B.BRENNER,T.KEATES,S.DAS,O.KING,R.CHALK,G.BERRIDGE,AUTH 4 F.VON DELFT,O.GILEADI,C.H.ARROWSMITH,A.M.EDWARDS,J.WEIGELT,AUTH 5 C.BOUNTRA,S.KNAPPTITL HUMAN VACCINIA-RELATED KINASE 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2l9r NKX3-1 solution nmr structure of homeobox domain of homeobox protein nkx-3.1 from homo sapiens, northeast structural genomics consortium target hr6470a -1.0Å AUTH G.LIU,R.XIAO,H.-W.LEE,K.HAMILTON,C.CICCOSANTI,H.B.WANG,AUTH 2 T.B.ACTON,J.K.EVERETT,Y.J.HUANG,G.T.MONTELIONETITL SOLUTION NMR STRUCTURE OF HOMEOBOX DOMAIN OF HOMEOBOXTITL 2 PROTEIN NKX-3.1 FROM HOMO SAPIENS, NORTHEAST STRUCTURALTITL 3 GENOMICS CONSORTIUM TARGET HR6470AREF TO BE PUBLISHEDREFN Variant Set […]
General Structure Information 2x6u TBX5 crystal structure of human tbx5 in the dna-free form 1.9Å AUTH C.U.STIRNIMANN,D.PTCHELKINE,C.GRIMM,C.W.MULLERTITL STRUCTURAL BASIS OF TBX5-DNA RECOGNITION: THE T-TITL 2 BOX DOMAIN IN ITS DNA-BOUND AND -UNBOUND FORM.REF J.MOL.BIOL. V. 400 71 2010REFN ISSN 0022-2836PMID 20450920DOI 10.1016/J.JMB.2010.04.052 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2rrf ZFYVE21 the solution structure of the c-terminal region of zinc finger fyve domain-containing protein 21 -1.0Å AUTH M.NAGANO,D.HOSHINO,S.KOSHIBA,T.SHUO,N.KOSHIKAWA,T.TOMIZAWA,AUTH 2 F.HAYASHI,N.TOCHIO,T.HARADA,T.AKIZAWA,S.WATANABE,N.HANDA,AUTH 3 M.SHIROUZU,T.KIGAWA,S.YOKOYAMA,M.SEIKITITL ZF21 PROTEIN, A REGULATOR OF THE DISASSEMBLY OF FOCALTITL 2 ADHESIONS AND CANCER METASTASIS, CONTAINS A NOVELTITL 3 NONCANONICAL PLECKSTRIN HOMOLOGY DOMAINREF J.BIOL.CHEM. V. 286 31598 2011REFN ISSN 0021-9258PMID […]
General Structure Information 3i2n WDR92 crystal structure of wd40 repeats protein wdr92 1.95Å AUTH C.XU,J.MINTITL STRUCTURE AND FUNCTION OF WD40 DOMAIN PROTEINS.REF PROTEIN CELL V. 2 202 2011REFN ISSN 1674-800XPMID 21468892DOI 10.1007/S13238-011-1018-1 Variant Set Distributions Mapped Variants
General Structure Information 3nr5 MAF1 crystal structure of human maf1 1.55Å AUTH A.VANNINI,R.RINGEL,A.G.KUSSER,O.BERNINGHAUSEN,AUTH 2 G.A.KASSAVETIS,P.CRAMERTITL MOLECULAR BASIS OF RNA POLYMERASE III TRANSCRIPTIONTITL 2 REPRESSION BY MAF1REF CELL(CAMBRIDGE,MASS.) V. 143 59 2010REFN ISSN 0092-8674PMID 20887893DOI 10.1016/J.CELL.2010.09.002 Variant Set Distributions Mapped Variants
General Structure Information 3vtw MAP1LC3B crystal structure of t7-tagged optineurin lir-fused human lc3b_2-119 2.52Å AUTH V.V.ROGOV,H.SUZUKI,E.FISKIN,P.WILD,A.KNISS,A.ROZENKNOP,AUTH 2 R.KATO,M.KAWASAKI,D.G.MCEWAN,F.LOHR,P.GUNTERT,I.DIKIC,AUTH 3 S.WAKATSUKI,V.DOTSCHTITL STRUCTURAL BASIS FOR PHOSPHORYLATION-TRIGGERED AUTOPHAGICTITL 2 CLEARANCE OF SALMONELLAREF BIOCHEM.J. V. 454 459 2013REFN ISSN 0264-6021PMID 23805866DOI 10.1042/BJ20121907 Variant Set Distributions Mapped Variants