Assessment of Structural Intolerance and Durability
General Structure Information 1whl CYLD solution structure of the 1st cap-gly domain in human cylindromatosis tumor suppressor cyld -1.0Å AUTH K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 1ST CAP-GLY DOMAIN INTITL 2 HUMAN CYLINDROMATOSIS TUMOR SUPPRESSOR CYLDREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3ega PELI2 crystal structure of pellino2 fha domain at 1.8 angstroms resolution 1.8Å AUTH C.C.LIN,Y.S.HUOH,K.R.SCHMITZ,L.E.JENSEN,K.M.FERGUSONTITL PELLINO PROTEINS CONTAIN A CRYPTIC FHA DOMAIN THAT MEDIATESTITL 2 INTERACTION WITH PHOSPHORYLATED IRAK1.REF STRUCTURE V. 16 1806 2008REFN ISSN 0969-2126PMID 19081057DOI 10.1016/J.STR.2008.09.011 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]
General Structure Information 1ugk SYT4 solution structure of the first c2 domain of synaptotagmin iv from human fetal brain (kiaa1342) -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,M.SHIROUZU,T.TERADA,T.KIGAWA,AUTH 2 M.INOUE,T.YABUKI,M.AOKI,E.SEKI,T.MATSUDA,H.HIROTA,AUTH 3 M.YOSHIDA,A.TANAKA,T.OSANAI,Y.MATSUO,O.OHARA,AUTH 4 T.NAGASE,R.KIKUNO,M.NAKAYAMA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST C2 DOMAIN OFTITL 2 SYNAPTOTAGMIN IV FROM HUMAN FETAL BRAIN (KIAA1342)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ebm RWDD1 solution structure of the rwd domain of human rwd domain containing protein 1 -1.0Å AUTH M.YONEYAMA,T.TOMIZAWA,S.KOSHIBA,S.WATABE,T.HARADA,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RWD DOMAIN OF HUMAN RWDTITL 2 DOMAIN CONTAINING PROTEIN 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2jqz SMURF2 solution structure of the c2 domain of human smurf2 -1.0Å AUTH S.WIESNER,A.A.OGUNJIMI,H.-R.WANG,D.ROTIN,F.SICHERI,AUTH 2 J.L.WRANA,J.D.FORMAN-KAYTITL AUTOINHIBITION OF THE HECT-TYPE UBIQUITIN LIGASETITL 2 SMURF2 THROUGH ITS C2 DOMAINREF CELL(CAMBRIDGE,MASS.) V. 130 651 2007REFN ISSN 0092-8674PMID 17719543DOI 10.1016/J.CELL.2007.06.050 Variant Set Distributions Mapped Variants
General Structure Information 2dnn RBM12 solution structure of rna binding domain in rna-binding protein 12 -1.0Å AUTH K.TSUDA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF RNA BINDING DOMAIN INTITL 2 RNA-BINDING PROTEIN 12REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2dhy CUEDC1 solution structure of the cue domain in the human cue domain containing protein 1 (cuedc1) -1.0Å AUTH C.ZHAO,T.KIGAWA,M.SATO,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CUE DOMAIN IN THE HUMANTITL 2 CUE DOMAIN CONTAINING PROTEIN 1 (CUEDC1)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4ccg FANCL structure of an e2-e3 complex 2.4Å AUTH C.HODSON,A.PURKISS,J.A.MILES,H.WALDENTITL STRUCTURE OF THE HUMAN FANCL RING-UBE2T COMPLEX REVEALSTITL 2 DETERMINANTS OF COGNATE E3-E2 SELECTION.REF STRUCTURE V. 22 337 2014REFN ISSN 0969-2126PMID 24389026DOI 10.1016/J.STR.2013.12.004 Variant Set Distributions Mapped Variants
General Structure Information 4ccg UBE2T structure of an e2-e3 complex 2.4Å AUTH C.HODSON,A.PURKISS,J.A.MILES,H.WALDENTITL STRUCTURE OF THE HUMAN FANCL RING-UBE2T COMPLEX REVEALSTITL 2 DETERMINANTS OF COGNATE E3-E2 SELECTION.REF STRUCTURE V. 22 337 2014REFN ISSN 0969-2126PMID 24389026DOI 10.1016/J.STR.2013.12.004 Variant Set Distributions Mapped Variants
General Structure Information 3kn1 GOLPH3 crystal structure of golgi phosphoprotein 3 n-term truncation variant 2.9Å AUTH C.S.WOOD,K.R.SCHMITZ,N.J.BESSMAN,T.G.SETTY,AUTH 2 K.M.FERGUSON,C.G.BURDTITL PTDINS4P RECOGNITION BY VPS74/GOLPH3 LINKS PTDINSTITL 2 4-KINASE SIGNALING TO RETROGRADE GOLGI TRAFFICKING.REF J.CELL BIOL. V. 187 967 2009REFN ISSN 0021-9525PMID 20026658DOI 10.1083/JCB.200909063 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants