Assessment of Structural Intolerance and Durability
General Structure Information 2qra XIAP crystal structure of xiap bir1 domain (p21 form) 2.5Å AUTH S.C.LIN,Y.HUANG,Y.C.LO,M.LU,H.WUTITL CRYSTAL STRUCTURE OF THE BIR1 DOMAIN OF XIAP INTITL 2 TWO CRYSTAL FORMSREF J.MOL.BIOL. V. 372 847 2007REFN ISSN 0022-2836PMID 17698078DOI 10.1016/J.JMB.2007.07.019 Variant Set Distributions Mapped Variants
General Structure Information 1wz0 SUMO2 solution structure of human sumo-2 (smt3b), a ubiquitin- like protein -1.0Å AUTH C.ZHAO,K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF HUMAN SUMO-2 (SMT3B), ATITL 2 UBIQUITIN-LIKE PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3dtc MAP3K9 crystal structure of mixed-lineage kinase mlk1 complexed with compound 16 2.6Å AUTH R.L.HUDKINS,J.L.DIEBOLD,M.TAO,K.A.JOSEF,C.H.PARK,AUTH 2 T.S.ANGELES,L.D.AIMONE,J.HUSTEN,M.A.ATOR,S.L.MEYER,AUTH 3 B.P.HOLSKIN,J.T.DURKIN,A.A.FEDOROV,E.V.FEDOROV,AUTH 4 S.C.ALMO,J.R.MATHIASEN,D.BOZYCZKO-COYNE,AUTH 5 M.S.SAPORITO,R.W.SCOTT,J.P.MALLAMOTITL MIXED-LINEAGE KINASE 1 AND MIXED-LINEAGE KINASE 3TITL 2 SUBTYPE-SELECTIVETITL 3 DIHYDRONAPHTHYL[3,4-A]PYRROLO[3,4-C]CARBAZOLE-5-TITL 4 ONES: OPTIMIZATION, MIXED-LINEAGE KINASE 1TITL 5 CRYSTALLOGRAPHY, AND ORAL IN VIVO ACTIVITY INTITL 6 1-METHYL-4-PHENYLTETRAHYDROPYRIDINE MODELS.REF J.MED.CHEM. […]
General Structure Information 4drz RAB14 crystal structure of human rab14 2.3Å AUTH J.WANG,W.TEMPEL,C.H.ARROWSMITH,A.M.EDWARDS,M.SUNDSTROM,AUTH 2 J.WEIGELT,A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN RAB14REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2c6b MDM2 solution structure of the c4 zinc-finger domain of hdm2 -1.0Å AUTH G.W.YU,M.D.ALLEN,A.ANDREEVA,A.R.FERSHT,M.BYCROFTTITL SOLUTION STRUCTURE OF THE C4 ZINC FINGER DOMAIN OFTITL 2 HDM2.REF PROTEIN SCI. V. 15 384 2006REFN ISSN 0961-8368PMID 16385008DOI 10.1110/PS.051927306 Variant Set Distributions Mapped Variants
General Structure Information 2kna XIAP solution structure of uba domain of xiap -1.0Å AUTH S.K.HUI,M.K.TSE,Y.YANG,B.C.WONG,K.H.SZETITL BACKBONE AND SIDE-CHAIN 1H, 13C AND 15N ASSIGNMENTS OF THETITL 2 UBIQUITIN-ASSOCIATED DOMAIN OF HUMAN X-LINKED INHIBITOR OFTITL 3 APOPTOSIS PROTEINREF BIOMOL.NMR ASSIGN. V. 4 13 2010REFN ISSN 1874-2718PMID 19916060DOI 10.1007/S12104-009-9197-X Variant Set Distributions Mapped Variants
General Structure Information 1ncv CCL7 determination cc-chemokine mcp-3, nmr, 7 structures -1.0Å AUTH S.MEUNIER,J.M.BERNASSAU,J.C.GUILLEMOT,P.FERRARA,AUTH 2 H.DARBONTITL DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURETITL 2 OF CC CHEMOKINE MONOCYTE CHEMOATTRACTANT PROTEIN 3TITL 3 BY 1H TWO-DIMENSIONAL NMR SPECTROSCOPY.REF BIOCHEMISTRY V. 36 4412 1997REFN ISSN 0006-2960PMID 9109648DOI 10.1021/BI9627929 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 1j1e TNNC1 crystal structure of the 52kda domain of human cardiac troponin in the ca2+ saturated form 3.3Å AUTH S.TAKEDA,A.YAMASHITA,K.MAEDA,Y.MAEDATITL STRUCTURE OF THE CORE DOMAIN OF HUMAN CARDIACTITL 2 TROPONIN IN THE CA2+-SATURATED FORMREF NATURE V. 424 35 2003REFN ISSN 0028-0836PMID 12840750DOI 10.1038/NATURE01780 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 3l6a EIF4G2 crystal structure of the c-terminal region of human p97 2.0Å AUTH S.FAN,M.JIA,W.GONGTITL CRYSTAL STRUCTURE OF THE C-TERMINAL REGION OF HUMANTITL 2 P97/DAP5REF PROTEINS 2010REFN ESSN 1097-0134DOI 10.1002/PROT.22735 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1vtn FOXA3 co-crystal structure of the hnf-3/fork head dna-recognition motif resembles histone h5 2.5Å AUTH K.L.CLARK,E.D.HALAY,E.LAI,S.K.BURLEYTITL CO-CRYSTAL STRUCTURE OF THE HNF-3/FORK HEAD DNA-RECOGNITIONTITL 2 MOTIF RESEMBLES HISTONE H5REF NATURE V. 364 412 1993REFN ISSN 0028-0836PMID 8332212DOI 10.1038/364412A0 Variant Set Distributions Mapped Variants