Assessment of Structural Intolerance and Durability
General Structure Information 3o34 HIST1H3J crystal structure of trim24 phd-bromo complexed with h3(13-32)k23ac peptide 1.9Å AUTH W.W.TSAI,Z.WANG,T.T.YIU,K.C.AKDEMIR,W.XIA,S.WINTER,C.Y.TSAI,AUTH 2 X.SHI,D.SCHWARZER,W.PLUNKETT,B.ARONOW,O.GOZANI,W.FISCHLE,AUTH 3 M.C.HUNG,D.J.PATEL,M.C.BARTONTITL TRIM24 LINKS A NON-CANONICAL HISTONE SIGNATURE TO BREASTTITL 2 CANCER.REF NATURE V. 468 927 2010REFN ISSN 0028-0836PMID 21164480DOI 10.1038/NATURE09542 Variant Set Distributions Mapped Variants
General Structure Information 3o34 HIST1H3D crystal structure of trim24 phd-bromo complexed with h3(13-32)k23ac peptide 1.9Å AUTH W.W.TSAI,Z.WANG,T.T.YIU,K.C.AKDEMIR,W.XIA,S.WINTER,C.Y.TSAI,AUTH 2 X.SHI,D.SCHWARZER,W.PLUNKETT,B.ARONOW,O.GOZANI,W.FISCHLE,AUTH 3 M.C.HUNG,D.J.PATEL,M.C.BARTONTITL TRIM24 LINKS A NON-CANONICAL HISTONE SIGNATURE TO BREASTTITL 2 CANCER.REF NATURE V. 468 927 2010REFN ISSN 0028-0836PMID 21164480DOI 10.1038/NATURE09542 Variant Set Distributions Mapped Variants
General Structure Information 4n0f FCGRT human fcrn complexed with human serum albumin 3.02Å AUTH V.OGANESYAN,M.M.DAMSCHRODER,K.E.COOK,Q.LI,C.GAO,H.WU,AUTH 2 W.F.DALLACQUATITL STRUCTURAL INSIGHTS INTO NEONATAL FC RECEPTOR-BASEDTITL 2 RECYCLING MECHANISMS.REF J.BIOL.CHEM. V. 289 7812 2014REFN ISSN 0021-9258PMID 24469444DOI 10.1074/JBC.M113.537563 Variant Set Distributions Mapped Variants
General Structure Information 3waa HIST4H4 the nucleosome containing human h2a.z.2 3.2Å AUTH N.HORIKOSHI,K.SATO,K.SHIMADA,Y.ARIMURA,A.OSAKABE,AUTH 2 H.TACHIWANA,Y.HAYASHI-TAKANAKA,W.IWASAKI,W.KAGAWA,M.HARATA,AUTH 3 H.KIMURA,H.KURUMIZAKATITL STRUCTURAL POLYMORPHISM IN THE L1 LOOP REGIONS OF HUMANTITL 2 H2A.Z.1 AND H2A.Z.2REF ACTA CRYSTALLOGR.,SECT.D V. 69 2431 2013REFN ISSN 0907-4449PMID 24311584DOI 10.1107/S090744491302252X Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3waa HIST1H4J the nucleosome containing human h2a.z.2 3.2Å AUTH N.HORIKOSHI,K.SATO,K.SHIMADA,Y.ARIMURA,A.OSAKABE,AUTH 2 H.TACHIWANA,Y.HAYASHI-TAKANAKA,W.IWASAKI,W.KAGAWA,M.HARATA,AUTH 3 H.KIMURA,H.KURUMIZAKATITL STRUCTURAL POLYMORPHISM IN THE L1 LOOP REGIONS OF HUMANTITL 2 H2A.Z.1 AND H2A.Z.2REF ACTA CRYSTALLOGR.,SECT.D V. 69 2431 2013REFN ISSN 0907-4449PMID 24311584DOI 10.1107/S090744491302252X Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3waa HIST1H4F the nucleosome containing human h2a.z.2 3.2Å AUTH N.HORIKOSHI,K.SATO,K.SHIMADA,Y.ARIMURA,A.OSAKABE,AUTH 2 H.TACHIWANA,Y.HAYASHI-TAKANAKA,W.IWASAKI,W.KAGAWA,M.HARATA,AUTH 3 H.KIMURA,H.KURUMIZAKATITL STRUCTURAL POLYMORPHISM IN THE L1 LOOP REGIONS OF HUMANTITL 2 H2A.Z.1 AND H2A.Z.2REF ACTA CRYSTALLOGR.,SECT.D V. 69 2431 2013REFN ISSN 0907-4449PMID 24311584DOI 10.1107/S090744491302252X Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3waa HIST1H4H the nucleosome containing human h2a.z.2 3.2Å AUTH N.HORIKOSHI,K.SATO,K.SHIMADA,Y.ARIMURA,A.OSAKABE,AUTH 2 H.TACHIWANA,Y.HAYASHI-TAKANAKA,W.IWASAKI,W.KAGAWA,M.HARATA,AUTH 3 H.KIMURA,H.KURUMIZAKATITL STRUCTURAL POLYMORPHISM IN THE L1 LOOP REGIONS OF HUMANTITL 2 H2A.Z.1 AND H2A.Z.2REF ACTA CRYSTALLOGR.,SECT.D V. 69 2431 2013REFN ISSN 0907-4449PMID 24311584DOI 10.1107/S090744491302252X Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3waa HIST1H4C the nucleosome containing human h2a.z.2 3.2Å AUTH N.HORIKOSHI,K.SATO,K.SHIMADA,Y.ARIMURA,A.OSAKABE,AUTH 2 H.TACHIWANA,Y.HAYASHI-TAKANAKA,W.IWASAKI,W.KAGAWA,M.HARATA,AUTH 3 H.KIMURA,H.KURUMIZAKATITL STRUCTURAL POLYMORPHISM IN THE L1 LOOP REGIONS OF HUMANTITL 2 H2A.Z.1 AND H2A.Z.2REF ACTA CRYSTALLOGR.,SECT.D V. 69 2431 2013REFN ISSN 0907-4449PMID 24311584DOI 10.1107/S090744491302252X Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1i4o CASP7 crystal structure of the xiap/caspase-7 complex 2.4Å AUTH Y.HUANG,Y.C.PARK,R.L.RICH,D.SEGAL,D.G.MYSZKA,H.WUTITL STRUCTURAL BASIS OF CASPASE INHIBITION BY XIAP: DIFFERENTIALTITL 2 ROLES OF THE LINKER VERSUS THE BIR DOMAIN.REF CELL(CAMBRIDGE,MASS.) V. 104 781 2001REFN ISSN 0092-8674PMID 11257231 Variant Set Distributions Mapped Variants
General Structure Information 3u5o HIST1H3H crystal structure of the complex of trim33 phd-bromo and h3(1-22) k9me3k14ack18ac histone peptide 2.7Å AUTH Q.XI,Z.WANG,A.I.ZAROMYTIDOU,X.H.ZHANG,L.F.CHOW-TSANG,AUTH 2 J.X.LIU,H.KIM,A.BARLAS,K.MANOVA-TODOROVA,V.KAARTINEN,AUTH 3 L.STUDER,W.MARK,D.J.PATEL,J.MASSAGUETITL A POISED CHROMATIN PLATFORM FOR TGF-BETA ACCESS TO MASTERTITL 2 REGULATORSREF CELL(CAMBRIDGE,MASS.) V. 147 1511 2011REFN ISSN 0092-8674PMID 22196728DOI 10.1016/J.CELL.2011.11.032 Variant Set Distributions Mapped Variants