General Structure Information
| PDB ID | 3waa |
| HGNC Gene Label(s) | HIST1H4C |
| Structure Name | the nucleosome containing human h2a.z.2 |
| Resolution | 3.2Å |
| Reference | AUTH N.HORIKOSHI,K.SATO,K.SHIMADA,Y.ARIMURA,A.OSAKABE,AUTH 2 H.TACHIWANA,Y.HAYASHI-TAKANAKA,W.IWASAKI,W.KAGAWA,M.HARATA,AUTH 3 H.KIMURA,H.KURUMIZAKATITL STRUCTURAL POLYMORPHISM IN THE L1 LOOP REGIONS OF HUMANTITL 2 H2A.Z.1 AND H2A.Z.2REF ACTA CRYSTALLOGR.,SECT.D V. 69 2431 2013REFN ISSN 0907-4449PMID 24311584DOI 10.1107/S090744491302252X |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 84 |
| Number Of SNVs | 61 |
| Number Of Permutations | 7050 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.152 |
| p-value | 0.18 |
COSMIC
| Number Of Residues | 84 |
| Number Of SNVs | 8 |
| Number Of Permutations | 1643 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.214 |
| p-value | 0.463 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 61 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | -0.344 |
| p-value | 0.076 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
