Assessment of Structural Intolerance and Durability
General Structure Information 2a2d GALK2 x-ray structure of human n-acetyl galactosamine kinase complexed with mn-amppnp and n-acetyl glactosamine 2.2Å AUTH J.B.THODEN,H.M.HOLDENTITL THE MOLECULAR ARCHITECTURE OF HUMANTITL 2 N-ACETYLGALACTOSAMINE KINASE.REF J.BIOL.CHEM. V. 280 32784 2005REFN ISSN 0021-9258PMID 16006554DOI 10.1074/JBC.M505730200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2a2d GALK2 x-ray structure of human n-acetyl galactosamine kinase complexed with mn-amppnp and n-acetyl glactosamine 2.2Å AUTH J.B.THODEN,H.M.HOLDENTITL THE MOLECULAR ARCHITECTURE OF HUMANTITL 2 N-ACETYLGALACTOSAMINE KINASE.REF J.BIOL.CHEM. V. 280 32784 2005REFN ISSN 0021-9258PMID 16006554DOI 10.1074/JBC.M505730200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2a2d GALK2 x-ray structure of human n-acetyl galactosamine kinase complexed with mn-amppnp and n-acetyl glactosamine 2.2Å AUTH J.B.THODEN,H.M.HOLDENTITL THE MOLECULAR ARCHITECTURE OF HUMANTITL 2 N-ACETYLGALACTOSAMINE KINASE.REF J.BIOL.CHEM. V. 280 32784 2005REFN ISSN 0021-9258PMID 16006554DOI 10.1074/JBC.M505730200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2eap LCP2 solution structure of the n-terminal sam-domain of human lymphocyte cytosolic protein 2 -1.0Å AUTH A.K.GORONCY,M.SATO,N.TOCHIO,S.KOSHIBA,S.WATANABE,AUTH 2 T.HARADA,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE N-TERMINAL SAM-DOMAIN OFTITL 2 HUMAN LYMPHOCYTE CYTOSOLIC PROTEIN 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1jfi DR1 crystal structure of the nc2-tbp-dna ternary complex 2.62Å AUTH K.KAMADA,F.SHU,H.CHEN,S.MALIK,G.STELZER,R.G.ROEDER,AUTH 2 M.MEISTERERNST,S.K.BURLEYTITL CRYSTAL STRUCTURE OF NEGATIVE COFACTOR 2TITL 2 RECOGNIZING THE TBP-DNA TRANSCRIPTION COMPLEX.REF CELL(CAMBRIDGE,MASS.) V. 106 71 2001REFN ISSN 0092-8674PMID 11461703DOI 10.1016/S0092-8674(01)00417-2 Variant Set Distributions Mapped Variants
General Structure Information 1jfi DR1 crystal structure of the nc2-tbp-dna ternary complex 2.62Å AUTH K.KAMADA,F.SHU,H.CHEN,S.MALIK,G.STELZER,R.G.ROEDER,AUTH 2 M.MEISTERERNST,S.K.BURLEYTITL CRYSTAL STRUCTURE OF NEGATIVE COFACTOR 2TITL 2 RECOGNIZING THE TBP-DNA TRANSCRIPTION COMPLEX.REF CELL(CAMBRIDGE,MASS.) V. 106 71 2001REFN ISSN 0092-8674PMID 11461703DOI 10.1016/S0092-8674(01)00417-2 Variant Set Distributions Mapped Variants
General Structure Information 1jfi DR1 crystal structure of the nc2-tbp-dna ternary complex 2.62Å AUTH K.KAMADA,F.SHU,H.CHEN,S.MALIK,G.STELZER,R.G.ROEDER,AUTH 2 M.MEISTERERNST,S.K.BURLEYTITL CRYSTAL STRUCTURE OF NEGATIVE COFACTOR 2TITL 2 RECOGNIZING THE TBP-DNA TRANSCRIPTION COMPLEX.REF CELL(CAMBRIDGE,MASS.) V. 106 71 2001REFN ISSN 0092-8674PMID 11461703DOI 10.1016/S0092-8674(01)00417-2 Variant Set Distributions Mapped Variants
General Structure Information 1jfi DR1 crystal structure of the nc2-tbp-dna ternary complex 2.62Å AUTH K.KAMADA,F.SHU,H.CHEN,S.MALIK,G.STELZER,R.G.ROEDER,AUTH 2 M.MEISTERERNST,S.K.BURLEYTITL CRYSTAL STRUCTURE OF NEGATIVE COFACTOR 2TITL 2 RECOGNIZING THE TBP-DNA TRANSCRIPTION COMPLEX.REF CELL(CAMBRIDGE,MASS.) V. 106 71 2001REFN ISSN 0092-8674PMID 11461703DOI 10.1016/S0092-8674(01)00417-2 Variant Set Distributions Mapped Variants
General Structure Information 1jfi DR1 crystal structure of the nc2-tbp-dna ternary complex 2.62Å AUTH K.KAMADA,F.SHU,H.CHEN,S.MALIK,G.STELZER,R.G.ROEDER,AUTH 2 M.MEISTERERNST,S.K.BURLEYTITL CRYSTAL STRUCTURE OF NEGATIVE COFACTOR 2TITL 2 RECOGNIZING THE TBP-DNA TRANSCRIPTION COMPLEX.REF CELL(CAMBRIDGE,MASS.) V. 106 71 2001REFN ISSN 0092-8674PMID 11461703DOI 10.1016/S0092-8674(01)00417-2 Variant Set Distributions Mapped Variants
General Structure Information 2pl3 DDX10 human dead-box rna helicase ddx10, dead domain in complex with adp 2.15Å AUTH P.SCHUTZ,T.KARLBERG,S.VAN DEN BERG,R.COLLINS,L.LEHTIO,AUTH 2 M.HOGBOM,L.HOLMBERG-SCHIAVONE,W.TEMPEL,H.W.PARK,AUTH 3 M.HAMMARSTROM,M.MOCHE,A.G.THORSELL,H.SCHULERTITL COMPARATIVE STRUCTURAL ANALYSIS OF HUMAN DEAD-BOX RNATITL 2 HELICASES.REF PLOS ONE V. 5 12791 2010REFN ESSN 1932-6203PMID 20941364DOI 10.1371/JOURNAL.PONE.0012791 Variant Set Distributions Mapped Variants