Assessment of Structural Intolerance and Durability
General Structure Information 4dck SCN5A crystal structure of the c-terminus of voltage-gated sodium channel in complex with fgf13 and cam 2.2Å AUTH C.WANG,B.C.CHUNG,H.YAN,S.Y.LEE,G.S.PITTTITL CRYSTAL STRUCTURE OF THE TERNARY COMPLEX OF A NAV C-TERMINALTITL 2 DOMAIN, A FIBROBLAST GROWTH FACTOR HOMOLOGOUS FACTOR, ANDTITL 3 CALMODULIN.REF STRUCTURE V. 20 1167 2012REFN ISSN 0969-2126PMID 22705208DOI 10.1016/J.STR.2012.05.001 Variant Set […]
General Structure Information 2c7s PTPRK crystal structure of human protein tyrosine phosphatase kappa at 1.95a resolution 1.95Å AUTH J.ESWARAN,J.E.DEBRECZENI,E.LONGMAN,A.BARR,S.KNAPPTITL THE CRYSTAL STRUCTURE OF HUMAN RECEPTOR PROTEIN TYROSINETITL 2 KAPPA PHOSPHATASE KAPPA DOMAIN 1.REF PROTEIN SCI. V. 15 1500 2006REFN ISSN 0961-8368PMID 16672235DOI 10.1110/PS.062128706 Variant Set Distributions Mapped Variants
General Structure Information 4hfx TCEB3 crystal structure of a transcription elongation factor b polypeptide 3 from homo sapiens, northeast structural genomics consortium target id hr4748b. 2.54Å AUTH J.SEETHARAMAN,M.SU,C CICCOSANTI,S SAHDEV,T.B.ACTON,R XIAO,AUTH 2 J.K EVERETT,G.T MONTELIONE,J.F.HUNT,L TONGTITL CRYSTAL STRUCTURE OF A TRANSCRIPTION ELONGATION FACTOR BTITL 2 POLYPEPTIDE 3 FROM HOMO SAPIENS, NORTHEAST STRUCTURALTITL 3 GENOMICS CONSORTIUM […]
General Structure Information 2hye CUL4A crystal structure of the ddb1-cul4a-rbx1-sv5v complex 3.1Å AUTH S.ANGERS,T.LI,X.YI,M.J.MACCOSS,R.T.MOON,N.ZHENGTITL MOLECULAR ARCHITECTURE AND ASSEMBLY OF THETITL 2 DDB1-CUL4A UBIQUITIN LIGASE MACHINERY.REF NATURE V. 443 590 2006REFN ISSN 0028-0836PMID 16964240DOI 10.1038/NATURE05175 Variant Set Distributions Mapped Variants
General Structure Information 2hye CUL4A crystal structure of the ddb1-cul4a-rbx1-sv5v complex 3.1Å AUTH S.ANGERS,T.LI,X.YI,M.J.MACCOSS,R.T.MOON,N.ZHENGTITL MOLECULAR ARCHITECTURE AND ASSEMBLY OF THETITL 2 DDB1-CUL4A UBIQUITIN LIGASE MACHINERY.REF NATURE V. 443 590 2006REFN ISSN 0028-0836PMID 16964240DOI 10.1038/NATURE05175 Variant Set Distributions Mapped Variants
General Structure Information 2hye CUL4A crystal structure of the ddb1-cul4a-rbx1-sv5v complex 3.1Å AUTH S.ANGERS,T.LI,X.YI,M.J.MACCOSS,R.T.MOON,N.ZHENGTITL MOLECULAR ARCHITECTURE AND ASSEMBLY OF THETITL 2 DDB1-CUL4A UBIQUITIN LIGASE MACHINERY.REF NATURE V. 443 590 2006REFN ISSN 0028-0836PMID 16964240DOI 10.1038/NATURE05175 Variant Set Distributions Mapped Variants
General Structure Information 3vww PDIA6 crystal structure of a0-domain of p5 from h. sapiens 1.93Å AUTH Y.SATO,R.KOJIMA,M.OKUMURA,M.HAGIWARA,S.MASUI,K.MAEGAWA,AUTH 2 M.SAIKI,T.HORIBE,M.SUZUKI,K.INABATITL SYNERGISTIC COOPERATION OF PDI FAMILY MEMBERS INTITL 2 PEROXIREDOXIN 4-DRIVEN OXIDATIVE PROTEIN FOLDINGREF SCI REP V. 3 2456 2013REFN ESSN 2045-2322PMID 23949117DOI 10.1038/SREP02456 Variant Set Distributions Mapped Variants
General Structure Information 4mjj DOC2A crystal structure of the c2a domain of doc2a 2.0Å AUTH Q.Q.HUANGTITL CRYSTAL STRUCTURE OF THE C2A DOMAIN OF DOC2AREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2cup FHL1 solution structure of the skeletal muscle lim-protein 1 -1.0Å AUTH T.N.NIRAULA,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SKELETAL MUSCLETITL 2 LIM-PROTEIN 1REF TO BE PUBLISHEDREFN Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3e3r CAPS crystal structure and biochemical characterization of recombinant human calcyphosine delineates a novel ef-hand-containing protein family 2.65Å AUTH H.DONG,X.LI,Z.LOU,X.XU,D.SU,X.ZHOU,W.ZHOU,M.BARTLAM,Z.RAOTITL CRYSTAL-STRUCTURE AND BIOCHEMICAL CHARACTERIZATION OFTITL 2 RECOMBINANT HUMAN CALCYPHOSINE DELINEATES A NOVELTITL 3 EF-HAND-CONTAINING PROTEIN FAMILYREF J.MOL.BIOL. V. 383 455 2008REFN ISSN 0022-2836PMID 18775726DOI 10.1016/J.JMB.2008.08.048 Variant Set Distributions Mapped Variants