Assessment of Structural Intolerance and Durability
General Structure Information 3n1p IHH crystal structure of ihhn bound to bocfn3 2.7Å AUTH J.M.KAVRAN,M.D.WARD,O.O.OLADOSU,S.MULEPATI,D.J.LEAHYTITL ALL MAMMALIAN HEDGEHOG PROTEINS INTERACT WITH CDO AND BOCTITL 2 IN A CONSERVED MANNER.REF J.BIOL.CHEM. 2010REFN ESSN 1083-351XPMID 20519495DOI 10.1074/JBC.M110.131680 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2dt6 SF3A1 solution structure of the first surp domain of human splicing factor sf3a120 -1.0Å AUTH K.KUWASAKO,F.HE,M.INOUE,A.TANAKA,S.SUGANO,AUTH 2 P.GUENTERT,Y.MUTO,S.YOKOYAMATITL SOLUTION STRUCTURES OF THE SURP DOMAINS AND THETITL 2 SUBUNIT-ASSEMBLY MECHANISM WITHIN THE SPLICINGTITL 3 FACTOR SF3A COMPLEX IN 17S U2 SNRNPREF STRUCTURE V. 14 1677 2006REFN ISSN 0969-2126PMID 17098193DOI 10.1016/J.STR.2006.09.009 Variant Set […]
General Structure Information 2odv PLEC crystal structure of a fragment of the plakin domain of plectin, cys to ala mutant. 2.05Å AUTH A.SONNENBERG,A.M.ROJAS,J.M.DE PEREDATITL THE STRUCTURE OF A TANDEM PAIR OF SPECTRIN REPEATS OFTITL 2 PLECTIN REVEALS A MODULAR ORGANIZATION OF THE PLAKIN DOMAIN.REF J.MOL.BIOL. V. 368 1379 2007REFN ISSN 0022-2836PMID 17397861DOI 10.1016/J.JMB.2007.02.090 Variant Set […]
General Structure Information 2odv PLEC crystal structure of a fragment of the plakin domain of plectin, cys to ala mutant. 2.05Å AUTH A.SONNENBERG,A.M.ROJAS,J.M.DE PEREDATITL THE STRUCTURE OF A TANDEM PAIR OF SPECTRIN REPEATS OFTITL 2 PLECTIN REVEALS A MODULAR ORGANIZATION OF THE PLAKIN DOMAIN.REF J.MOL.BIOL. V. 368 1379 2007REFN ISSN 0022-2836PMID 17397861DOI 10.1016/J.JMB.2007.02.090 Variant Set […]
General Structure Information 2odv PLEC crystal structure of a fragment of the plakin domain of plectin, cys to ala mutant. 2.05Å AUTH A.SONNENBERG,A.M.ROJAS,J.M.DE PEREDATITL THE STRUCTURE OF A TANDEM PAIR OF SPECTRIN REPEATS OFTITL 2 PLECTIN REVEALS A MODULAR ORGANIZATION OF THE PLAKIN DOMAIN.REF J.MOL.BIOL. V. 368 1379 2007REFN ISSN 0022-2836PMID 17397861DOI 10.1016/J.JMB.2007.02.090 Variant Set […]
General Structure Information 2epw ZNF268 solution structure of the 24th c2h2 type zinc finger domain of zinc finger protein 268 -1.0Å AUTH W.TANABE,S.SUZUKI,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 24TH C2H2 TYPE ZINCTITL 2 FINGER DOMAIN OF ZINC FINGER PROTEIN 268REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3a77 IRF3 the crystal structure of phosphorylated irf-3 1.8Å AUTH K.TAKAHASI,M.HORIUCHI,K.FUJII,S.NAKAMURA,N.N.NODA,AUTH 2 M.YONEYAMA,T.FUJITA,F.INAGAKITITL SER386 PHOSPHORYLATION OF TRANSCRIPTION FACTOR IRF-3 INDUCESTITL 2 DIMERIZATION AND ASSOCIATION WITH CBP/P300 WITHOUT OVERALLTITL 3 CONFORMATIONAL CHANGE.REF GENES CELLS V. 15 901 2010REFN ISSN 1356-9597PMID 20604809DOI 10.1111/J.1365-2443.2010.01427.X Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 3u82 PVRL1 binding of herpes simplex virus glycoprotein d to nectin-1 exploits host cell adhesion 3.16Å AUTH N.ZHANG,J.YAN,G.LU,Z.GUO,Z.FAN,J.WANG,Y.SHI,J.QI,G.F.GAOTITL BINDING OF HERPES SIMPLEX VIRUS GLYCOPROTEIN D TO NECTIN-1TITL 2 EXPLOITS HOST CELL ADHESION.REF NAT COMMUN V. 2 577 2011REFN ESSN 2041-1723PMID 22146396DOI 10.1038/NCOMMS1571 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 3u82 PVRL1 binding of herpes simplex virus glycoprotein d to nectin-1 exploits host cell adhesion 3.16Å AUTH N.ZHANG,J.YAN,G.LU,Z.GUO,Z.FAN,J.WANG,Y.SHI,J.QI,G.F.GAOTITL BINDING OF HERPES SIMPLEX VIRUS GLYCOPROTEIN D TO NECTIN-1TITL 2 EXPLOITS HOST CELL ADHESION.REF NAT COMMUN V. 2 577 2011REFN ESSN 2041-1723PMID 22146396DOI 10.1038/NCOMMS1571 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 3u82 PVRL1 binding of herpes simplex virus glycoprotein d to nectin-1 exploits host cell adhesion 3.16Å AUTH N.ZHANG,J.YAN,G.LU,Z.GUO,Z.FAN,J.WANG,Y.SHI,J.QI,G.F.GAOTITL BINDING OF HERPES SIMPLEX VIRUS GLYCOPROTEIN D TO NECTIN-1TITL 2 EXPLOITS HOST CELL ADHESION.REF NAT COMMUN V. 2 577 2011REFN ESSN 2041-1723PMID 22146396DOI 10.1038/NCOMMS1571 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]