Assessment of Structural Intolerance and Durability
General Structure Information 1jo6 KCNMB2 solution structure of the cytoplasmic n-terminus of the bk beta-subunit kcnmb2 -1.0Å AUTH D.BENTROP,M.BEYERMANN,R.WISSMANN,B.FAKLERTITL NMR STRUCTURE OF THE BALL-AND-CHAIN DOMAIN OFTITL 2 KCNMB2, THE BETA 2-SUBUNIT OF LARGE CONDUCTANCETITL 3 CA2+- AND VOLTAGE-ACTIVATED POTASSIUM CHANNELS.REF J.BIOL.CHEM. V. 276 42116 2001REFN ISSN 0021-9258PMID 11517232DOI 10.1074/JBC.M107118200 Variant Set Distributions Mapped Variants
General Structure Information 3ltl ARFGEF1 crystal structure of human big1 sec7 domain 2.2Å AUTH J.C.ZEEH,P.C.SIMISTER,V.ROUSSEAU,A.JOUBERT,J.CHERFILS,V.BIOUTITL THE SEC7 DOMAIN STRUCTURES OF HUMAN BIG1 AND CYTOHESIN1 ARFTITL 2 NUCLEOTIDE EXCHANGE FACTORSREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3bin EPB41L3 structure of the dal-1 and tslc1 (372-383) complex 2.3Å AUTH R.D.BUSAM,A.-G.THORSELL,A.FLORES,M.HAMMARSTROM,C.PERSSON,AUTH 2 B.OBRINK,B.M.HALLBERGTITL STRUCTURAL BASIS OF TUMOR SUPPRESSOR IN LUNG CANCER 1TITL 2 (TSLC1) BINDING TO DIFFERENTIALLY EXPRESSED INTITL 3 ADENOCARCINOMA OF THE LUNG (DAL-1/4.1B)REF J.BIOL.CHEM. V. 286 4511 2011REFN ISSN 0021-9258PMID 21131357DOI 10.1074/JBC.M110.174011 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 3t9l USP15 structure of n-terminal dusp-ubl domains of human usp15 1.5Å AUTH S.HARPER,T.M.BESONG,J.EMSLEY,D.J.SCOTT,I.DREVENYTITL STRUCTURE OF THE USP15 N-TERMINAL DOMAINS: A BETA-HAIRPINTITL 2 MEDIATES CLOSE ASSOCIATION BETWEEN THE DUSP AND UBL DOMAINSREF BIOCHEMISTRY V. 50 7995 2011REFN ISSN 0006-2960PMID 21848306DOI 10.1021/BI200726E Variant Set Distributions Mapped Variants
General Structure Information 1wfg RIMS2 pdz domain of human rim2b -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL PDZ DOMAIN OF HUMAN RIM2BREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3evx UFC1 crystal structure of the human e2-like ubiquitin-fold modifier conjugating enzyme 1 (ufc1). northeast structural genomics consortium target hr41 2.54Å AUTH G.LIU,F.FOROUHAR,A.ELETSKY,H.S.ATREYA,J.M.ARAMINI,AUTH 2 R.XIAO,Y.J.HUANG,M.ABASHIDZE,J.SEETHARAMAN,J.LIU,AUTH 3 B.ROST,T.ACTON,G.T.MONTELIONE,J.F.HUNT,T.SZYPERSKITITL NMR AND X-RAY STRUCTURES OF HUMAN E2-LIKETITL 2 UBIQUITIN-FOLD MODIFIER CONJUGATING ENZYME 1TITL 3 (UFC1) REVEAL STRUCTURAL AND FUNCTIONALTITL 4 CONSERVATION IN THE METAZOAN UFM1-UBA5-UFC1TITL […]
General Structure Information 2qz4 SPG7 human paraplegin, aaa domain in complex with adp 2.22Å AUTH T.KARLBERG,S.VAN DEN BERG,M.HAMMARSTROM,J.SAGEMARK,AUTH 2 I.JOHANSSON,L.HOLMBERG-SCHIAVONE,H.SCHULERTITL CRYSTAL STRUCTURE OF THE ATPASE DOMAIN OF THE HUMAN AAA+TITL 2 PROTEIN PARAPLEGIN/SPG7.REF PLOS ONE V. 4 E6975 2009REFN ESSN 1932-6203PMID 19841671DOI 10.1371/JOURNAL.PONE.0006975 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2zmv TRAPPC4 crystal structure of synbindin 2.8Å AUTH S.FAN,Z.WEI,H.XU,W.GONGTITL CRYSTAL STRUCTURE OF HUMAN SYNBINDIN REVEALS TWOTITL 2 CONFORMATIONS OF LONGIN DOMAINREF BIOCHEM.BIOPHYS.RES.COMMUN. V. 378 338 2009REFN ISSN 0006-291XPMID 18466758DOI 10.1016/J.BBRC.2008.04.143 Variant Set Distributions Mapped Variants
General Structure Information 3ex7 RBM8A the crystal structure of ejc in its transition state 2.3Å AUTH K.H.NIELSEN,H.CHAMIEH,C.B.ANDERSEN,F.FREDSLUND,AUTH 2 K.HAMBORG,H.LE HIR,G.R.ANDERSENTITL MECHANISM OF ATP TURNOVER INHIBITION IN THE EJCREF RNA V. 15 67 2009REFN ISSN 1355-8382PMID 19033377DOI 10.1261/RNA.1283109 Variant Set Distributions Mapped Variants
General Structure Information 2dgx KIAA0430 solution structure of the rna recognition motif in kiaa0430 protein -1.0Å AUTH C.ABE,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,M.SHIROUZU,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RNA RECOGNITION MOTIF INTITL 2 KIAA0430 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants