Assessment of Structural Intolerance and Durability
General Structure Information 2coz CEP350 solution structure of the cap-gly domain in human centrosome-associated protein cap350 -1.0Å AUTH K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CAP-GLY DOMAIN IN HUMANTITL 2 CENTROSOME-ASSOCIATED PROTEIN CAP350REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2hzp KYNU crystal structure of homo sapiens kynureninase 2.0Å AUTH S.LIMA,R.KHRISTOFOROV,C.MOMANY,R.S.PHILLIPSTITL CRYSTAL STRUCTURE OF HOMO SAPIENS KYNURENINASE.REF BIOCHEMISTRY V. 46 2735 2007REFN ISSN 0006-2960PMID 17300176DOI 10.1021/BI0616697 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1v1c OBSCN solution structure of the sh3 domain of obscurin -1.0Å AUTH M.PFUHL,M.GAUTELTITL SOLUTION STRUCTURE OF THE SH3 DOMAIN OF OBSCURINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2y1h TATDN3 crystal structure of the human tatd-domain protein 3 (tatdn3) 2.5Å AUTH J.R.C.MUNIZ,S.PURANIK,T.KROJER,W.W.YUE,E.UGOCHUKWU,AUTH 2 P.FILIPPAKOPOULOS,F.VON DELFT,C.H.ARROWSMITH,A.M.EDWARDS,AUTH 3 J.WEIGELT,C.BOUNTRA,K.L.KAVANAGH,U.OPPERMANNTITL CRYSTAL STRUCTURE OF THE HUMAN TATD-DOMAIN PROTEIN 3TITL 2 (TATDN3)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3soo L1TD1 crystal structure of a line-1 type transposase domain-containing protein 1 (l1td1) from homo sapiens at 2.73 a resolution 2.73Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 2 PARTNERSHIP FOR STEM CELL BIOLOGY (STEMCELL)TITL CRYSTAL STRUCTURE OF A LINE-1 TYPE TRANSPOSASETITL 2 DOMAIN-CONTAINING PROTEIN 1 (L1TD1) FROM HOMO SAPIENS ATTITL 3 […]
General Structure Information 4bq7 RGMB crystal structure of the rgmb-neo1 complex form 2 6.6Å AUTH C.H.BELL,E.HEALEY,S.VAN ERP,B.BISHOP,C.TANG,R.J.C.GILBERT,AUTH 2 A.R.ARICESCU,R.J.PASTERKAMP,C.SIEBOLDTITL STRUCTURE OF THE REPULSIVE GUIDANCE MOLECULE (RGM)-NEOGENINTITL 2 SIGNALING HUBREF SCIENCE V. 341 77 2013REFN ISSN 0036-8075PMID 23744777DOI 10.1126/SCIENCE.1232322 Variant Set Distributions Mapped Variants
General Structure Information 2lpn CDNF solution structure of n-terminal domain of human conserved dopamine neurotrophic factor (cdnf) -1.0Å AUTH C.LATGE,K.M.CABRAL,M.S.ALMEIDA,D.FOGUELTITL (1)H-, (13)C- AND (15)N-NMR ASSIGNMENT OF THE N-TERMINALTITL 2 DOMAIN OF HUMAN CEREBRAL DOPAMINE NEUROTROPHIC FACTORTITL 3 (CDNF).REF BIOMOL.NMR ASSIGN. V. 7 101 2013REFN ISSN 1874-2718PMID 22528768DOI 10.1007/S12104-012-9388-8 Variant Set Distributions Mapped Variants
General Structure Information 4mtl METTL21C human methyltransferase-like protein 21c 1.65Å AUTH B.S.HONG,W.TEMPEL,A.DONG,Y.LI,C.H.ARROWSMITH,C.BOUNTRA,AUTH 2 A.M.EDWARDS,P.J.BROWNTITL HUMAN METHYLTRANSFERASE-LIKE PROTEIN 21CREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3iai CA9 crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase ix 2.2Å AUTH V.ALTERIO,M.HILVO,A.DI FIORE,C.T.SUPURAN,P.PAN,S.PARKKILA,AUTH 2 A.SCALONI,J.PASTOREK,S.PASTOREKOVA,C.PEDONE,A.SCOZZAFAVA,AUTH 3 S.M.MONTI,G.DE SIMONETITL CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THETITL 2 TUMOR-ASSOCIATED HUMAN CARBONIC ANHYDRASE IX.REF PROC.NATL.ACAD.SCI.USA V. 106 16233 2009REFN ISSN 0027-8424PMID 19805286DOI 10.1073/PNAS.0908301106 Variant Set Distributions Mapped Variants
General Structure Information 1uhc DNMBP solution structure of rsgi ruh-002, a sh3 domain of kiaa1010 protein [homo sapiens] -1.0Å AUTH T.ABE,H.HIROTA,N.KOBAYASHI,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-002, A SH3 DOMAINTITL 2 OF KIAA1010 PROTEIN [HOMO SAPIENS]REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants