Assessment of Structural Intolerance and Durability
General Structure Information 2yrb RPGRIP1L solution structure of the first c2 domain from human kiaa1005 protein -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST C2 DOMAIN FROMTITL 2 HUMAN KIAA1005 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2z13 EFHC2 crystal structure of the n-terminal duf1126 in human ef- hand domain 1.84Å AUTH K.SAITO,S.KISHISHITA,A.NISHINO,K.MURAYAMA,T.TERADA,AUTH 2 M.SHIROUZU,T.KIGAWA,S.YOKOYAMATITL CRYSTAL STRUCTURE OF THE N-TERMINAL DUF1126 INTITL 2 HUMAN EF-HAND DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4c0a IQSEC1 arf1(delta1-17)in complex with brag2 sec7-ph domain 3.3Å AUTH K.AIZEL,V.BIOU,J.NAVAZA,L.V.DUARTE,V.CAMPANACCI,J.CHERFILS,AUTH 2 M.ZEGHOUFTITL INTEGRATED CONFORMATIONAL AND LIPID-SENSING REGULATION OFTITL 2 ENDOSOMAL ARFGEF BRAG2.REF PLOS BIOL. V. 11 01652 2013REFN ISSN 1544-9173PMID 24058294DOI 10.1371/JOURNAL.PBIO.1001652 Variant Set Distributions Mapped Variants
General Structure Information 3hzj RABGAP1L crystal structure of the rabgap domain of the rabgap1l protein 2.3Å AUTH L.NEDYALKOVA,W.TEMPEL,Y.TONG,N.ZHONG,F.MACKENZIE,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE RABGAP DOMAIN OF THETITL 2 RABGAP1L PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2i1y PTPRN crystal structure of the phosphatase domain of human ptp ia-2 2.23Å AUTH S.C.ALMO,J.B.BONANNO,J.M.SAUDER,S.EMTAGE,T.P.DILORENZO,AUTH 2 V.MALASHKEVICH,S.R.WASSERMAN,S.SWAMINATHAN,S.ESWARAMOORTHY,AUTH 3 R.AGARWAL,D.KUMARAN,M.MADEGOWDA,S.RAGUMANI,Y.PATSKOVSKY,AUTH 4 J.ALVARADO,U.A.RAMAGOPAL,J.FABER-BARATA,M.R.CHANCE,A.SALI,AUTH 5 A.FISER,Z.Y.ZHANG,D.S.LAWRENCE,S.K.BURLEYTITL STRUCTURAL GENOMICS OF PROTEIN PHOSPHATASESREF J.STRUCT.FUNCT.GENOM. V. 8 121 2007REFN ISSN 1345-711XPMID 18058037DOI 10.1007/S10969-007-9036-1 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2edt OBSCN solution structure of the ig-like domain (3449-3537) from human obscurin -1.0Å AUTH K.SEIMIYA,K IZUMI,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE IG-LIKE DOMAINTITL 2 (3449-3537) FROM HUMAN OBSCURINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2g6z DUSP5 crystal structure of human dusp5 2.7Å AUTH D.G.JEONG,Y.H.CHO,T.S.YOON,J.H.KIM,S.E.RYU,S.J.KIMTITL CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMANTITL 2 DUSP5, A DUAL SPECIFICITY MAP KINASE PROTEINTITL 3 PHOSPHATASEREF PROTEINS V. 66 253 2007REFN ISSN 0887-3585PMID 17078075DOI 10.1002/PROT.21224 Variant Set Distributions Mapped Variants
General Structure Information 2ox8 COLEC12 human scavenger receptor c-type lectin carbohydrate- recognition domain. 2.5Å AUTH H.FEINBERG,M.E.TAYLOR,W.I.WEISTITL SCAVENGER RECEPTOR C-TYPE LECTIN BINDS TO THETITL 2 LEUKOCYTE CELL SURFACE GLYCAN LEWIS(X) BY A NOVELTITL 3 MECHANISM.REF J.BIOL.CHEM. V. 282 17250 2007REFN ISSN 0021-9258PMID 17420244DOI 10.1074/JBC.M701624200 Variant Set Distributions Mapped Variants
General Structure Information 3nbq UPP1 human uridine phosphorylase 1 (hupp1) with 5-fluorouracil 2.3Å AUTH T.P.ROOSILD,S.CASTRONOVOTITL ACTIVE SITE CONFORMATIONAL DYNAMICS IN HUMAN URIDINETITL 2 PHOSPHORYLASE 1.REF PLOS ONE V. 5 E1274 2010REFN ESSN 1932-6203PMID 20856879DOI 10.1371/JOURNAL.PONE.0012741 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2mdg ZNF423 solution nmr structure of zinc finger protein 423 from homo sapiens, northeast structural genomics consortium (nesg) target hr7298f -1.0Å AUTH K.PEDERSON,D.LEE,E.KOHAN,H.JANJUA,R.XIAO,J.K.EVERETT,AUTH 2 T.B.ACTON,G.T.MONTELIONE,J.H.PRESTEGARDTITL SOLUTION NMR STRUCTURE OF ZINC FINGER PROTEIN 423 FROM HOMOTITL 2 SAPIENS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG)TITL 3 TARGET HR7298FREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped […]