Assessment of Structural Intolerance and Durability
General Structure Information 4ggd CDC20 structural analysis of human cdc20 supports multisite degron recognition by apc/c. 2.44Å AUTH W.TIAN,B.LI,R.WARRINGTON,D.R.TOMCHICK,H.YU,X.LUOTITL STRUCTURAL ANALYSIS OF HUMAN CDC20 SUPPORTS MULTISITE DEGRONTITL 2 RECOGNITION BY APC/C.REF PROC.NATL.ACAD.SCI.USA V. 109 18419 2012REFN ISSN 0027-8424PMID 23091007DOI 10.1073/PNAS.1213438109 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1o8r GUCA2A solution structure of human proguanylin -1.0Å AUTH T.LAUBER,P.NEUDECKER,P.ROESCH,U.C.MARXTITL SOLUTION STRUCTURE OF HUMAN PROGUANYLIN: THE ROLETITL 2 OF A HORMONE PROSEQUENCEREF J.BIOL.CHEM. V. 278 24118 2003REFN ISSN 0021-9258PMID 12707255DOI 10.1074/JBC.M300370200 Variant Set Distributions Mapped Variants
General Structure Information 3ezz DUSP4 crystal structure of human mkp-2 2.9Å AUTH D.G.JEONG,S.K.JUNG,T.S.YOON,E.J.WOO,J.H.KIM,AUTH 2 B.C.PARK,S.E.RYU,S.J.KIMTITL CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMANTITL 2 MKP-2 REVEALS A 24-MER ASSEMBLY.REF PROTEINS V. 76 763 2009REFN ISSN 0887-3585PMID 19415758DOI 10.1002/PROT.22423 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 4a60 FABP9 crystal structure of human testis-specific fatty acid binding protein 9 (fabp9) 1.53Å AUTH J.R.C.MUNIZ,W.KIYANI,L.SHRESTHA,D.S.FROESE,T.KROJER,AUTH 2 M.VOLLMAR,C.H.ARROWSMITH,A.M.EDWARDS,J.WEIGELT,C.BOUNTRA,AUTH 3 F.VON DELFT,W.W.YUETITL THE CRYSTAL STRUCTURE OF THE HUMAN FABP9AREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3vyx DHX9 structural insights into risc assembly facilitated by dsrna binding domains of human rna helicase (dhx9) 2.29Å AUTH Q.FU,Y.A.YUANTITL STRUCTURAL INSIGHTS INTO RISC ASSEMBLY FACILITATED BYTITL 2 DSRNA-BINDING DOMAINS OF HUMAN RNA HELICASE A (DHX9)REF NUCLEIC ACIDS RES. 2013REFN ESSN 1362-4962PMID 23361462DOI 10.1093/NAR/GKT042 Variant Set Distributions Mapped Variants
General Structure Information 3zd2 CFHR1 the structure of the two n-terminal domains of complement factor h related protein 1 shows formation of a novel dimerisation interface 1.99Å AUTH E.GOICOECHEA DE JORGE,J.J.E.CAESAR,T.H.MALIK,M.PATEL,AUTH 2 M.COLLEDGE,S.JOHNSON,S.HAKOBYAN,B.P.MORGAN,C.L.HARRIS,AUTH 3 M.C.PICKERING,S.M.LEATITL DIMERIZATION OF COMPLEMENT FACTOR H-RELATED PROTEINSTITL 2 MODULATES COMPLEMENT ACTIVATION IN VIVO.REF PROC.NATL.ACAD.SCI.USA V. 110 4685 2013REFN ISSN 0027-8424PMID 23487775DOI […]
General Structure Information 3nf1 KLC1 crystal structure of the tpr domain of kinesin light chain 1 2.8Å AUTH Y.TONG,W.TEMPEL,L.SHEN,Y.SHEN,L.NEDYALKOVA,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE TPR DOMAIN OF KINESIN LIGHT CHAIN 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1yb5 CRYZ crystal structure of human zeta-crystallin with bound nadp 1.85Å AUTH J.DEBRECZENI,G.BERRIDGE,K.KAVANAGH,S.COLBROOK,J.BRAY,AUTH 2 L.WILLIAMS,U.OPPERMANN,M.SUNDSTROM,C.ARROWSMITH,A.EDWARDS,AUTH 3 O.GILEADI,F.VON DELFTTITL CRYSTAL STRUCTURE OF HUMAN ZETA-CRYSTALLIN AT 1.85AREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1buo ZBTB16 btb domain from plzf 1.9Å AUTH K.F.AHMAD,C.K.ENGEL,G.G.PRIVETITL CRYSTAL STRUCTURE OF THE BTB DOMAIN FROM PLZF.REF PROC.NATL.ACAD.SCI.USA V. 95 12123 1998REFN ISSN 0027-8424PMID 9770450DOI 10.1073/PNAS.95.21.12123 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4fww MST1R crystal structure of the sema-psi extracellular domains of human ron receptor tyrosine kinase 1.85Å AUTH K.L.CHAO,I.W.TSAI,C.CHEN,O.HERZBERGTITL CRYSTAL STRUCTURE OF THE SEMA-PSI EXTRACELLULAR DOMAIN OFTITL 2 HUMAN RON RECEPTOR TYROSINE KINASE.REF PLOS ONE V. 7 41912 2012REFN ESSN 1932-6203PMID 22848655DOI 10.1371/JOURNAL.PONE.0041912 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]