Assessment of Structural Intolerance and Durability
General Structure Information 1rrj TOP1 structural mechanisms of camptothecin resistance by mutations in human topoisomerase i 2.3Å AUTH J.E.CHRENCIK,B.L.STAKER,A.B.BURGIN,P.POURQUIER,AUTH 2 Y.POMMIER,L.STEWART,M.R.REDINBOTITL MECHANISMS OF CAMPTOTHECIN RESISTANCE BY HUMANTITL 2 TOPOISOMERASE I MUTATIONSREF J.MOL.BIOL. V. 339 773 2004REFN ISSN 0022-2836PMID 15165849DOI 10.1016/J.JMB.2004.03.077 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1erv TXN human thioredoxin mutant with cys 73 replaced by ser (reduced form) 1.65Å AUTH A.WEICHSEL,J.R.GASDASKA,G.POWIS,W.R.MONTFORTTITL CRYSTAL STRUCTURES OF REDUCED, OXIDIZED, ANDTITL 2 MUTATED HUMAN THIOREDOXINS: EVIDENCE FOR ATITL 3 REGULATORY HOMODIMER.REF STRUCTURE V. 4 735 1996REFN ISSN 0969-2126PMID 8805557DOI 10.1016/S0969-2126(96)00079-2 Variant Set Distributions Mapped Variants
General Structure Information 2cv5 HIST1H2BK crystal structure of human nucleosome core particle 2.5Å AUTH Y.TSUNAKA,N.KAJIMURA,S.TATE,K.MORIKAWATITL ALTERATION OF THE NUCLEOSOMAL DNA PATH IN THETITL 2 CRYSTAL STRUCTURE OF A HUMAN NUCLEOSOME CORETITL 3 PARTICLEREF NUCLEIC ACIDS RES. V. 33 3424 2005REFN ISSN 0305-1048PMID 15951514DOI 10.1093/NAR/GKI663 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]