Assessment of Structural Intolerance and Durability
General Structure Information 3s2k DKK1 structural basis of wnt signaling inhibition by dickkopf binding to lrp5/6. 2.8Å AUTH V.E.AHN,M.L.CHU,H.J.CHOI,D.TRAN,A.ABO,W.I.WEISTITL STRUCTURAL BASIS OF WNT SIGNALING INHIBITION BY DICKKOPFTITL 2 BINDING TO LRP5/6.REF DEV.CELL V. 21 862 2011REFN ISSN 1534-5807PMID 22000856DOI 10.1016/J.DEVCEL.2011.09.003 Variant Set Distributions Mapped Variants
General Structure Information 3s2k LRP6 structural basis of wnt signaling inhibition by dickkopf binding to lrp5/6. 2.8Å AUTH V.E.AHN,M.L.CHU,H.J.CHOI,D.TRAN,A.ABO,W.I.WEISTITL STRUCTURAL BASIS OF WNT SIGNALING INHIBITION BY DICKKOPFTITL 2 BINDING TO LRP5/6.REF DEV.CELL V. 21 862 2011REFN ISSN 1534-5807PMID 22000856DOI 10.1016/J.DEVCEL.2011.09.003 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants